CALDOVIS 500MG contains Calcium dobesilate which belongs to the group of medicines called Vasoprotective agents. It is used to treat microangiopathies such as diabetic retinopathy, hemorrhoidal syndrome (condition of inflamed and swollen blood vessels in rectum or around anus), chronic venous insufficiency/vascular dysfunction (condition of leg veins in which blood gets pooled in the legs due to failure of valves present in leg veins presenting with pain, cramps, and inactivity of legs) and adjuvant to superficial thrombophlebitis (causing clot in superficial veins) and other microcirculation disorders of arteriovenous origin.
Microangiopathy or microcirculation disorder is a disease of small blood vessels in which walls of those vessels become weak and bleed, resulting in reduced blood flow. In diabetic retinopathy, microangiopathy reduces the blood flow to retina, causing floaters (dark spots in the vision), blurred vision or even blindness.
CALDOVIS 500MG is not recommended for use in patients who are allergic to calcium dobesilate. It should be used with caution in patients with liver diseases such as obstructive jaundice, diabetic retinopathy (eye disorder that occurs due to diabetes), venous disorder such as varicose veins (enlarged veins in legs and feet), and dialysis patients with serious renal failure. CALDOVIS 500MG is not recommended for use in pregnant and breastfeeding women, also it should be used with caution in children and adolescents (below 18 years of age). Consult your doctor before taking it. The most common side effects associated with the use of CALDOVIS 500MG are fever, bloating, constipation, diarrhoea, pain, nausea, vomiting and arthralgia (joint pain). Consult your doctor if any of the symptom worsens.
CALDOVIS 500MG works by reducing the permeability or leakage in the blood vessels by acting on collagen chains, resulting in strengthening of the vessel walls which also reduces the action of the chemical messengers that increase the permeability of vessel walls, thereby resulting in reduced bleeding in small vessels.
Take CALDOVIS 500MG as advised by your physician. Swallow the medicine with a glass of water and take this medicine along with food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking CALDOVIS 500MG and contact your doctor if you experience any of the following side effects:
Diarrhoea:
Drink lot of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhoea and consult your doctor if the symptom gets worse.
Nausea and vomiting:
Try to take CALDOVIS 500MG with or just after a meal or a snack. Stick to simple meals. Avoid eating oily, fried or spicy foods. Consult your doctor if the symptom gets worse.
Itching:
Tap or pat your skin upon itching. Try not to scratch the itchy skin. Take cool or warm bath and place cool damp towel on the skin. Wear loose cotton clothes. Avoid using perfumed moisturizers, deodorants or soaps.
Constipation:
Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom gets worse.
CALDOVIS 500MG is not recommended for use in pregnant women unless it is considered clearly necessary. Consult your doctor before taking it.
CALDOVIS 500MG is not recommended for use if you are breastfeeding since it may pass into the breast milk. Consult your doctor before taking CALDOVIS 500MG.
CALDOVIS 500MG is unlikely to affect your ability to drive and use of machines. Consult your doctor before taking it.
CALDOVIS 500MG should be used with caution in patients undergoing dialysis with serious renal failure. Consult your doctor for advice before taking CALDOVIS 500MG.
CALDOVIS 500MG should be used with caution in patients with liver diseases such as obstructive jaundice. Consult your doctor before taking it.
CALDOVIS 500MG is not recommended for use if you are allergic to Calcium dobesilate, or any other ingredients of this medicine.
Before taking CALDOVIS 500MG, inform your doctor if you have:
Use in Paediatrics:
CALDOVIS 500MG should be used with caution in children and adolescents (below 18 years of age). Consult child’s doctor for advice.
Use in Geriatrics:
CALDOVIS 500MG should be used with caution in elderly patients (aged 65 and above). Consult your doctor before taking it.
A. Drug-Drug Interactions:
Before taking CALDOVIS 500MG, inform your doctor if you are taking any medicines including prescription or non-prescription medicines, herbals or vitamin supplements.
Overdosage:
If you or anyone else accidentally takes too much of CALDOVIS 500MG, consult your doctor immediately or visit the nearby hospital if you experience any unusual symptoms.
Drug | : | Calcium dobesilate |
Pharmacological Category | : | Vasoprotective agent |
Therapeutic Indication | : | Microangiopathy or microcirculation disorder |
Dosage Forms | : | Capsule |
What is CALDOVIS 500MG used for?
CALDOVIS 500MG is used to treat microangiopathies such as diabetic retinopathy (loss of vision due to diabetes), hemorrhoidal syndrome (swelling of veins in lower rectum or anus), chronic venous insufficiency (presenting with pain, cramps, and inactivity of legs) and adjuvant to superficial thrombophlebitis, and other microcirculation disorders. Consult your doctor before taking CALDOVIS 500MG.
Is CALDOVIS 500MG safe to use in children and elderly?
CALDOVIS 500MG should be used with caution in children and adolescents (below 18 years of age) and in elderly patients (above 65 years of age). Consult your doctor for advice before taking CALDOVIS 500MG.
Is CALDOVIS 500MG safe to use in patients undergoing dialysis?
CALDOVIS 500MG should be used with caution in dialysis patients with serious renal failure. In such cases dose can be reduced accordingly. Consult your doctor for advice before taking CALDOVIS 500MG.
How does CALDOVIS 500MG work?
CALDOVIS 500MG helps in treating small blood vessel disorders and haemorrhoids, where calcium dobesilate works by reducing the permeability or leakage in the blood vessels by acting on collagen chains, resulting in strengthening of the vessel walls. It also reduces the action of the chemical messengers that increase the permeability of vessel walls, thereby resulting in reduced bleeding in small vessels.
Can CALDOVIS 500MG be taken during pregnancy or breast feeding?
CALDOVIS 500MG is not recommended for use in pregnant women unless it is clearly advised by your doctor. It is also not recommended for use in breastfeeding mothers as it may pass into breast milk. Consult your doctor before taking it.
When should I stop taking CALDOVIS 500MG?
Stop taking CALDOVIS 500MG and contact your doctor immediately, if you experience any signs of agranulocytosis (high fever, oral cavity infections, sore throat, and/or anogenital inflammation), and signs of infection (fever, chills, sweats and cough), skin rash, fever and bone pain.
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3. E Rabe, K A Jaeger, M Bulitta, F Pannier. Calcium dobesilate in patients suffering from chronic venous insufficiency: a double-blind, placebo-controlled, clinical trial. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. June 2011. [Accessed on 8th July 2022] https://pubmed.ncbi.nlm.nih.gov/21478142/
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