Bucelon 2Mg Tablet 25's

Cancer/Oncology Rx required
OUT OF STOCK

Best Price* ₹ 76.00 MRP ₹ 95.00
(Inclusive of all taxes) *25 Tablet(s) in a Strip * Mkt: Celon Laboratories Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

BUCELON 2MG contains Busulfan which belongs to the group of medicines called Anti-cancer agents. It is used to treat certain types of blood cancer such as chronic myeloid leukemia (cancer of white blood cells in the blood), polycythemia vera (cancer of red blood cells in the blood) and thrombocythemia (increased platelet levels).

It can also be used to treat bone marrow cancer (such as myelofibrosis). When used prior to haemopoietic progenitor stem cell transplantation, BUCELON 2MG can suppress the functions of immune cells (white blood cells) and prevent transplant rejection among patients who have a high WBC count or leukemia.

Before taking BUCELON 2MG inform your doctor if you have any lung, liver, or kidney problems. You must also inform your doctor if you recently had radiotherapy for cancer or having gout or any other blood problems.

BUCELON 2MG should not be used in pregnant or breastfeeding women due to increased risk of side effects. Both men and women receiving BUCELON 2MG must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with BUCELON 2MG.

The most common side effects of taking BUCELON 2MG are nausea, vomiting, mouth sores, diarrhea, hair loss, decrease in blood cell count and infertility. Consult your doctor if any of these side effects worsen.

USES OF BUCELON 2MG

It is used to:

  • Treat blood cancer (chronic myeloid leukemia, polycythemia vera and thrombocythemia)
  • Treat bone marrow cancer (myelofibrosis)
  • Prevent transplant rejection when given to patients who have high WBC count prior to haemopoietic progenitor stem cell transplantation

HOW BUCELON 2MG WORKS

BUCELON 2MG is an anticancer medicine. It acts by damaging the genetic material (DNA) of cancer cells. This prevents the cancer cells from growing and multiplying within the body. When used prior to stem cell transplantation, BUCELON 2MG can also suppress the functions of immune cells (white blood cells) among patients who have a high WBC count or leukemia.

DIRECTIONS FOR USE

Take BUCELON 2MG as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF BUCELON 2MG

COMMON

  • nausea, vomiting
  • diarrhoea
  • mouth ulcers
  • decrease in blood cells (red blood cells, white blood cells and platelets)
  • hair loss
  • visible dark patches of the skin
  • lung inflammation (pneumonitis, pneumonia syndrome)
  • infertility both in men and women (causing lack of periods, early menopause, low sperm production)
  • delayed puberty in girls
  • yellowing of skin and whites of eye (jaundice) and liver damage
  • heart rhythm problems
  • bloody urine or difficulty in urination

RARE

  • fits (seizures)
  • eye problems or cataract
  • dry mouth
  • skin rashes, dry or itching skin

Stop taking BUCELON 2MG and contact your doctor immediately if you experience any of the following side effects:

  • any signs of fever or infection (chills, sore throat, mouth sores, cough, urinary problems)
  • abnormal bleeding and bruising (discoloration of skin)
  • sudden feeling of unwellness

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Take BUCELON 2MG with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your vomiting worsens.

Diarrhoea:

Drink plenty of fluids such as water, fruit juices or electrolytes to avoid dehydration in your body. Consult your doctor if your symptom worsens.

Mouth ulcers:

Use soft toothbrush to brush your teeth. Avoid eating spicy and acidic foods such as beverages, sodas, and processed foods. Also, you may can use over-the-counter pain relieving oral gel to get some relief.

WARNING & PRECAUTIONS

PREGNANCY

BUCELON 2MG is not recommended for use in pregnant women. Women of childbearing age must use a suitable contraceptive before and during treatment with BUCELON 2MG to avoid pregnancy.

BREASTFEEDING

BUCELON 2MG is not recommended for use in breastfeeding women. However, consult your doctor before taking it.

DRIVING AND USING MACHINES

BUCELON 2MG does not cause any side effects that affects your ability to drive or operate any machines. If you experience any side effects that impairs your ability to concentrate, avoid driving and operating machines.

ALCOHOL

Consumption of alcohol is not recommended during treatment with BUCELON 2MG.

KIDNEY

BUCELON 2MG should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

LIVER

BUCELON 2MG should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take BUCELON 2MG if you are allergic to Busulfan.

LUNGS

BUCELON 2MG should be used with caution in patients with lung problems. Therefore, consult your doctor before taking it.

OTHERS

Before taking BUCELON 2MG inform your doctor if you have:

  • recently undergone radiation therapy for cancer treatment
  • inherited thalassemia (blood disorder results in low levels of hemoglobin in blood)
  • ever had gout (joint pain due to accumulation of uric acid in joints)

Use in pediatrics:

BUCELON 2MG should be used in children and adolescents (aged below 18 years) only if prescribed by a physician. Therefore, consult your doctor before administration.

Use in geriatrics:

BUCELON 2MG should be used with caution in elderly patients. Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug interactions:

Before taking BUCELON 2MG inform your doctor, if you are taking any of the following medicines such as:

  • other chemotherapy medicines (used to treat cancer) such as cyclophosphamide, cisplatin, carboplatin, methotrexate
  • itraconazole (a medicine used to treat fungal infections)
  • metronidazole (a medicine used to treat bacterial and protozoal infections)
  • phenytoin (a medicine used to prevent and treat fits)
  • deferasirox (a medicine used to remove excess iron from the body)
  • live-attenuated vaccines to prevent infections (such as oral polio, MMR vaccine)
  • paracetamol (used to treat fever and pain)
  • anesthetics (used to cause numbness before surgery) Ex. lidocaine, enflurane, isoflurane, propofol

Overdosage:

If you or anyone else accidentally took more BUCELON 2MG, consult your doctor or visit the nearby hospital immediately. Overdosage may cause symptoms such as nausea, vomiting, diarrhea, decreased activity of bone marrow and low levels of blood cells.

SYNOPSIS

Drug :   Busulfan        
Pharmacological Category :  

Alkylating agents

Therapeutic Indication :   Blood cancer, Bone Marrow Cancer
Dosage Forms :   Tablet, Injection

MORE INFORMATION

  • Keep BUCELON 2MG out of reach of children
  • Store BUCELON 2MG at room temperature and not above 25°C

FAQs ABOUT BUCELON 2MG

What is the use of BUCELON 2MG?

BUCELON 2MG is an anticancer medicine used to treat blood cancer and bone marrow cancer. It can also be used to suppress the function of immune cells prior to stem cell transplantation in patients with high WBC count or leukemia.

Is BUCELON 2MG a chemotherapy?

Yes. BUCELON 2MG is a chemotherapy. It acts by preventing the growth and multiplication of cancer cells within the body.

Is the use of BUCELON 2MG safe?

BUCELON 2MG is safe when used under proper medical supervision and at the prescribed doses.

What are the side effects of BUCELON 2MG?

BUCELON 2MG may cause abnormal decrease in WBC and platelet counts. It may also cause nausea, vomiting, diarrhea, mouth sores and fertility problems. Therefore, consult your doctor for advice if they trouble you.

Will BUCELON 2MG help in curing cancer?

Yes. BUCELON 2MG is an anticancer medicine used to treat blood cancer and bone marrow cancer. It can also be used to suppress the function of immune cells prior to stem cell transplantation in patients with high WBC count or leukemia.

How long will it take for BUCELON 2MG to cure my disease?

The time taken for cure depends upon the intensity of the disease. Contact your doctor regarding the duration of the therapy.

How BUCELON 2MG works?

BUCELON 2MG acts by damaging the genetic material (DNA) of cancer cells. This prevents the cancer cells from growing and multiplying within the body. When used prior to stem cell transplantation, BUCELON 2MG can also suppress the functions of immune cells (white blood cells) among patients who have a high WBC count or leukemia.

Can the use of BUCELON 2MG cause hair loss?

Yes. Hair loss is one of the common side effects of taking a chemotherapy medicine like BUCELON 2MG. Consult your doctor if it bothers you.

Will the use of BUCELON 2MG affect fertility?

Yes. The use of BUCELON 2MG affects fertility in both men and women. It may cause lack of periods, delayed puberty, early menopause in women and decreased sperm production in men. Consult your doctor if they trouble you.

Can I stop taking BUCELON 2MG without consulting your doctor?

No, you should not stop taking BUCELON 2MG without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using BUCELON 2MG, consult your doctor for advice. Your doctor might would reduce the dose gradually before discontinuation of therapy.

Will taking a higher dose of BUCELON 2MG be more effective?

No, taking a higher dose of BUCELON 2MG will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

What to do if I forget to take a dose of BUCELON 2MG?

If you forget to take a dose of BUCELON 2MG, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of BUCELON 2MG to compensate a missed dose, as it could lead to toxicity.

REFERENCES

1. KD. Tripathi. Chemotherapy of Neoplastic Diseases. Essentials of medical pharmacology. Seventh edition. 2013. Page – 861.

2. Alan L Myers, Jitesh D Kawedia, Richard E Champlin, Mark A Kramer, Yago Nieto, Romi Ghose and Borje S Andersson. Clarifying Busulfan Metabolism and Drug Interactions to Support New Therapeutic Drug Monitoring Strategies: A Comprehensive Review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. August 2017. [Accessed on 3rd September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584057/

3. EXCELLA GmbH & Co. KG. Electronic Medicines Compendium (EMC). [Revised in July 2020] [Accessed on 3rd September 2022] https://www.medicines.org.uk/emc/files/pil.4653.pdf

4. Aspen Pharma Trading Limited. Health Products Regulatory Agency. [Revised in July 2020]. [Accessed on 3rd September 2022] https://www.hpra.ie/img/uploaded/swedocuments/e31a77f5-a7ce-4259-8e8d-18bae56a21e4.pdf

USEFUL DIAGNOSTIC TESTS

  • Bcr-Abl Gene Translocation
  • Complete Blood Count
  • Peripheral Smear Examination

PRODUCT DETAILS

    Net Qty
    1 N
    Ingredient
    BUSULPHAN 2MG
    Hsn Code
    30049099
ALTERNATE BRANDS
MYLEFAN 2mg Tablet 10's
Prescription Cancer/Oncology Rx required
Out of stock
Rs.249.00
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