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INTRODUCTION
BONACORT 40MG INJECTION contains Triamcinolone which belongs to the group of medicines called Corticosteroids. It is used to treat pain, swelling and stiffness in joints as seen in various disorders such as Rheumatoid Arthritis. It is also used to treat various allergic disorders such as asthma, hormonal problems, rheumatic fever and various disorders of the digestive system, skin, kidneys and lungs.
BONACORT 40MG INJECTION is not recommended if you are diagnosed with any condition affecting the kidney, liver and thyroid gland or any infection, hypertension and heart failure. Before taking BONACORT 40MG INJECTION, inform your doctor if you have/had infection recently such as Tuberculosis (TB), diabetes, bowel surgery, stomach ulcer and/or a bowel disorder, inflamed veins or infection in legs, mental health disorder, epilepsy, any form of cancer, osteoporosis (thick and brittle bones, myasthenia gravis, glaucoma, have visual disturbances, loss of vision, inflammation of the retina (viral retinitis) or of eyes (red, bloodshot eyes) etc.
BONACORT 40MG INJECTION is not recommended for use in children below 6 years of age. Also, pregnant and nursing women are recommended to inform the doctor about their pregnancy and breastfeeding status, before receiving BONACORT 40MG INJECTION. The most common side effects of taking BONACORT 40MG INJECTION are increased risk of infection, reaction at the site reaction, headache and pain in joints. Consult your doctor if any of your symptoms get worse or persist.
USES OF BONACORT 40MG INJECTION
- Treats joint pain, swelling and stiffness in various disorders such as rheumatoid arthritis
- Treats various allergic disorders such as asthma
- Treats hormonal problems
- Treats rheumatic fever
- Treats disorders of the digestive system, skin, kidneys and lungs
HOW BONACORT 40MG INJECTION WORKS
BONACORT 40MG INJECTION is used to inhibit the synthesis of various chemicals that cause inflammation namely prostaglandins and leukotrienes. It works by decreasing the expression of cyclo-oxygenase, lipoxygenase enzymes, responsible for their production. It also decreases the activity of a certain nuclear factor called kappa-B which leads to decreased production of interleukin 6 and 8, which are pro-inflammatory substances.
DIRECTIONS FOR USE
BONACORT 40MG INJECTION will be given to you only by a doctor or a nurse in the muscles or joints. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF BONACORT 40MG INJECTION
COMMON
- increased risk of infection
- reaction at the site reaction
- headache
- pain in joints
UNCOMMON
- altered blood chemicals causing fluid retention
- heart failure
- irregular heartbeat
- weak muscles or bones
- compromised healing of broken bones
- destroyed ends of bones
- decreased muscle mass
- muscle or bone pain
- muscular weakness or discomfort
- fractures
- loss of bone tissue (osteoporosis)
- thin and fragile skin
- development of rashes, stretch marks, bruises, itchy bumps
- sweating, flushing and increased hair growth
- loss/darkening of skin color
- indigestion
- pain, ulceration and pain stomach along with bloating
- increased appetite and weight loss
- inflammation of the pancreas/esophagus
- bleeding in the stomach
- eye problems such as inflammation, glaucoma, cataracts, blindness, bulging of the eye, damage to the cornea or white of the eye
- infection of the nose
- irregular periods
- vaginal bleeding in postmenopausal women
- viral or fungal eye infections
- yeast infections such as thrush
- tiredness
- sensation of tingling
- increased pressure in the brain
- increased appetite
- weight loss
- decreased tolerance to carbohydrates
- mild form of diabetes with no obvious symptoms
- inadequately controlled diabetes mellitus
- increased blood sugar
- onset of pain, swelling along with worsening of the pain in the injected joint
- impaired healing
- increased body temperature
- disrupted production of hormones
- slow or absent of growth in children
- increased or decreased hormone production by certain glands
- vertigo
- altered blood pressure
- abnormal blood clots
- worsened longstanding chronic infections such as tuberculosis
RARE
Stop receiving BONACORT 40MG INJECTION and consult your doctor immediately if you experience any of the following:
- changes in mood
- mental health disorders
- feeling of dependency on the medicine
- troubled sleep
- fits or epilepsy
- feeling dizzy
- fainting
- feeling depressed
- thoughts about suicide
- feelings of euphoria and mania
- mood changes
- feeling anxious/irritable
- difficulty in thinking and confusion
- loss of memory
- feeling, seeing, or hearing things that do not exist
- having strange and frightening thoughts
HOW TO MANAGE SIDE EFFECTS
Nausea And Vomiting
Stick to simple meals. Avoid eating heavily rich or spicy food. Drink oral rehydration solution to compensate for the loss of water and minerals. Stay hydrated. Consult your doctor if it persists or gets worse.
Headache
Stay hydrated and avoid taking products rich in caffeine and avoid harsh lights and loud sounds. Apply a pain-relieving balm on the forehead if needed. Consult your doctor if your symptom gets worse or persist.
Tiredness
Stay hydrated and also maintain an adequate intake of electrolytes throughout the day. Also, take a nutrient-rich diet and healthy calories to sustain energy throughout the day. Consult your doctor if it persists or gets worse.
Visual Disturbances
Keep your spectacles and contact lenses and lens case clean. Also, wash your eyes frequently with water and try to reduce the time spent in front of the screen. Pay a visit to a doctor if the problem worsens or gets prolonged. Consult your doctor if it persists or gets worse.
Weight Gain
Eat healthy and well-balanced meals throughout the day which are packed with healthy and vital nutrients and vitamins. Also, moderate physical exercise is recommended. Consult your doctor if it persists or gets worse.
Indigestion
Stick to simple meals. Avoid eating heavily rich or spicy food. Stay hydrated. Consult your doctor if it persists or gets worse.
WARNING & PRECAUTIONS
PREGNANCY
Consult your doctorIt is recommended to consult the doctor before receiving BONACORT 40MG INJECTION if you are pregnant or planning pregnancy.
BREASTFEEDING
Consult your doctorIt is recommended to consult your doctor before receiving BONACORT 40MG INJECTION, if you are a nursing mother.
DRIVING AND USING MACHINES
Use with CautionIt is recommended not to drive or use machinery after receiving BONACORT 40MG INJECTION as causes disturbances in vision. Consult your doctor before receiving it.
KIDNEY
ContraindicatedIt is not recommended to receive BONACORT 40MG INJECTION if you have any disorder of kidney. Consult your doctor before receiving it.
LIVER
ContraindicatedIt is not recommended to receive BONACORT 40MG INJECTION if you have any disorder of liver. Consult before receiving it.
ALLERGY
ContraindicatedIt is not recommended to receive BONACORT 40MG INJECTION if you are allergic to Triamcinolone and/or any other constituent found in BONACORT 40MG INJECTION. Consult your doctor before receiving it.
HEART DISEASE
ContraindicatedIt is not recommended to receive BONACORT 40MG INJECTION if you have increased blood pressure or heart failure. Consulted your doctor before receiving it.
OTHERS
BONACORT 40MG INJECTION is not recommended for use if you:
- are suffering from an infection and are not receiving any medication for it
Before taking BONACORT 40MG INJECTION, inform your doctor if you:
- recently had an infection such as Tuberculosis (TB)
- had bowel surgery recently
- have or ever had a stomach ulcer and/or a bowel disorder
- have inflamed veins or infection in legs
- have disorderly mental health
- have epilepsy
- have or had any disorder of the kidney, liver or thyroid gland
- recently had any form of cancer
- have osteoporosis, which is a disorder characterized by thick and brittle bones
- have myasthenia gravis, which is a disease characterized by weak muscles
- are diagnosed with glaucoma, have visual disturbances, loss of vision, inflammation of the retina (viral retinitis) or of eyes (red, bloodshot eyes)
- have a family history of glaucoma
- have diabetes or if your dosage needs to be changed
Use in Pediatrics:
BONACORT 40MG INJECTION is not recommended for use in children less than the age of 6. Consult your doctor for advice.
INTERACTIONS
A. Drug-Drug Interactions:
Before taking BONACORT 40MG INJECTION, inform your doctor if you are taking any of the following medicine:
- medicines used to treat HIV (Ex. ritonavir, cobicistat)
- medicines used to treat pain and inflammation (Ex. aspirin, ibuprofen)
- medicines used to treat fungal infections (Ex. clarithromycin, ketoconazole etc.)
- medicines used to thin the blood (Ex. warfarin)
- medicines used for contraception or as hormone replacement therapy (HRT) (Ex. estrogen)
- medicines used to treat tuberculosis (rifampicin)
- medicines used to suppress the immune response (Ex. ciclosporin)
- medicines used to treat increased blood pressure and irregular heartbeat (Ex. Digoxin)
- medicines used to treat myasthenia gravis (Ex. pyridostigmine)
- medicines used to treat epilepsy and fits (Ex. phenytoin)
- medicines used to treat diabetes (Ex. insulin, metformin)
- medicines used to treat disorders of the thyroid gland (Ex. levothyroxine, liothyronine)
Overdosage:
BONACORT 40MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
SYNOPSIS
| Drug | : | Triamcinolone |
| Pharmacological Category | : | Anti Inflammatory |
| Therapeutic Indication | : | Rheumatoid Arthritis, Asthma, Rheumatic fever, disorders of the skin, kidneys, lungs and digestive system |
| Dosage Forms | : | Buccal paste, cream, gel, ointment, injection, lotion, tablet, oral paste, mouth paint, paste, oral gel |
MORE INFORMATION
- Keep BONACORT 40MG INJECTION out of reach and sight from children
- Do not store it above the temperature of 25°C
FAQs ABOUT BONACORT 40MG INJECTION
Q. Can BONACORT 40MG INJECTION be given to infants?
A. No, BONACORT 40MG INJECTION is not recommended for children below the age of 6. For children above the age of 6 and adults, your doctor will decide the correct dose or select a suitable alternative therapy for your child.
Q. Can I self-administer BONACORT 40MG INJECTION at my home?
A. No, BONACORT 40MG INJECTION is administered only by a doctor or a nurse in the muscles or joints. Do not self-administer it at home. Consult your doctor for advice.
Q. Can I stop receiving BONACORT 40MG INJECTION if I feel better?
A. BONACORT 40MG INJECTION is a steroid medication, Treatment with steroids should not be abruptly stopped as it may lead to various adverse effects. The dosage of BONACORT 40MG INJECTION is to be gradually reduced.
Q. What are the precautions I should follow during the course of my treatment with BONACORT 40MG INJECTION?
A. During the course of treatment with BONACORT 40MG INJECTION, stay away from people who have chickenpox or shingles if you never had it in past as it could have severe effects. Visit a doctor immediately, if you come in contact with a person having it. Also, do not have any vaccinations without your doctor’s consent while receiving BONACORT 40MG INJECTION.
Q. Do I need to follow a special diet while receiving BONACORT 40MG INJECTION?
A. If you are receiving long-term intramuscular treatment with BONACORT 40MG INJECTION, it is recommended to include more proteins in your diet. It is so because long-term treatment with steroids can result in gradual loss of weight.
Q. What happens after stopping the BONACORT 40MG INJECTION treatment?
A. After the termination of your treatment with BONACORT 40MG INJECTION, there can be the development of certain flu-like symptoms, runny nose or itchy eyes and skin. Usually, after the cessation of treatment with BONACORT 40MG INJECTION, your doctor may ask you to take oral steroids for a while.
Q. Does BONACORT 40MG INJECTION cause mental illness?
A. Yes, BONACORT 40MG INJECTION is reported to cause mental illness if taken at higher doses. It generally goes away by lowering the dosage. Also, report to a doctor if you feel depressed and have suicidal thoughts.
REFERENCES
1. KD Tripathi. Corticosteroids. Essentials of medical pharmacology. Seventh edition. 2013. Page – 287-289.
2. Wang, S., Wang, X., Liu, Y., Sun, X. and Tang, Y., 2019. Ultrasound-guided intra-articular triamcinolone acetonide injection for treating refractory small joints arthritis of rheumatoid arthritis patients. [Published on 16th August 2019] [Accessed on 2nd February 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831351/
3. Bristol-Myers Squibb Pharmaceuticals Unlimited Company. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 2nd February 2023] https://www.medicines.org.uk/emc/files/pil.6748.pdf
4. DrugBank. Triamcinolone. [Accessed on 2nd February 2023] https://go.drugbank.com/drugs/DB00620
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