INTRODUCTION

BIOGESIC AP ORANGE FLAVOUR SUSPENSION is a combination of Aceclofenac and Paracetamol, which belongs to the group of medicines called Non-steroidal anti-inflammatory drugs. BIOGESIC AP ORANGE FLAVOUR SUSPENSION is used in pediatric patients to reduce inflammation and provide relief from pain from conditions such as mild migraine, headaches, dental pain, muscle pain, rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

It is also used in paediatric patients to treat fever.

BIOGESIC AP ORANGE FLAVOUR SUSPENSION is not recommended for use in child allergic to aceclofenac and paracetamol. It is also not recommended for use in children with lung problems (such as asthma), heart problems, kidney problems, and/or liver problems.

BIOGESIC AP ORANGE FLAVOUR SUSPENSION is not recommended for use in pregnant and breastfeeding women since it is used only in children and adolescents (aged below 18 years). It is also not recommended for use in elderly patients.

The most common side effects of administering BIOGESIC AP ORANGE FLAVOUR SUSPENSION are diarrhoea, indigestion, abdominal pain, nausea, flatulence, constipation, and/or drowsiness. Consult your doctor if any of these symptoms becomes worse in the child.

USES OF BIOGESIC AP ORANGE FLAVOUR SUSPENSION

Used in pediatric patients:

• To reduce inflammation and provide relief from pain from conditions such as mild migraine, headaches, dental pain, muscle pain, rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis
• To treat fever

HOW BIOGESIC AP ORANGE FLAVOUR SUSPENSION WORKS

BIOGESIC AP ORANGE FLAVOUR SUSPENSION provides relief from pain and reduces fever where aceclofenac and paracetamol works by blocking the action of prostaglandin (chemical messengers responsible for pain, fever and inflammation) thus reducing fever and providing relief from fever in affected children.

DIRECTIONS FOR USE

Administer BIOGESIC AP ORANGE FLAVOUR SUSPENSION in child as directed by your physician. Shake well before use. Your doctor will decide the correct dose and duration for your child depending upon the age, body weight and disease condition.

SIDE EFFECTS OF BIOGESIC AP ORANGE FLAVOUR SUSPENSION

HOW TO MANAGE SIDE EFFECTS

Nausea/vomiting:

Have the child take this medicine with or just after a meal or a snack. Let the child stick to simple meals and avoid having rich or spicy food.

Constipation:

Ask the child to drink adequate amount of water and include plenty of fruits and vegetables in child’s diet. Constipation should go away after few days followed by its administration in the child. If it persists for longer time or becomes severe then consult your doctor.

Diarrhoea: 

Ask the child to drink lots of fluids such as water or fruit juices so that the child is sufficiently hydrated. Do not administer any medicine to treat the condition. Consult your doctor if the symptom does not improve or becomes worse.

Dizziness:

Ask your child to take rest and get enough sleep. Provide child with a glass of fruit juice or water to improve dizziness Consult your doctor if the symptom does not improve or becomes worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before administering BIOGESIC AP ORANGE FLAVOUR SUSPENSION, inform your doctor if your child is taking any of the following medicine:

• Domperidone, metoclopramide (medicines used to nausea, vomiting)
• Cholestyramine (used to reduce high cholesterol levels in blood)
• Medicines used to thin blood (Ex. warfarin)
• Medicines used for epilepsy (Ex. barbiturates)
• Medicines for depression such as tricyclic antidepressants (Ex. amitriptyline, amoxapine)
• Flucloxacillin (used for skin and wound infections, bone infections)

Overdosage:

If the child or anyone else accidentally take too much of BIOGESIC AP ORANGE FLAVOUR SUSPENSION, consult and inform your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep BIOGESIC AP ORANGE FLAVOUR SUSPENSION out of reach of children
• Store BIOGESIC AP ORANGE FLAVOUR SUSPENSION at a temperature below 25°C

FAQs ABOUT BIOGESIC AP ORANGE FLAVOUR SUSPENSION

What is BIOGESIC AP ORANGE FLAVOUR SUSPENSION used for?

BIOGESIC AP ORANGE FLAVOUR SUSPENSION is used in paediatric patients to reduce inflammation and provide relief from pain from conditions (such as mild migraine, headaches, dental pain, muscle pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis) which is also used in paediatric patients to treat fever.

How BIOGESIC AP ORANGE FLAVOUR SUSPENSION works?

BIOGESIC AP ORANGE FLAVOUR SUSPENSION provides relief from pain and reduces fever where aceclofenac and paracetamol works by blocking the action of prostaglandin (chemical messengers responsible for pain, fever and inflammation) thus reducing fever and providing relief from fever in affected children.

What are the most common side effects of taking BIOGESIC AP ORANGE FLAVOUR SUSPENSION?

The most common side effects of administering BIOGESIC AP ORANGE FLAVOUR SUSPENSION are diarrhoea, indigestion, abdominal pain, nausea, flatulence, constipation, and/or drowsiness. Consult your doctor if any of these symptoms becomes worse in the child.

What happens to the child if high dose BIOGESIC AP ORANGE FLAVOUR SUSPENSION is administered?

If child or anyone else accidentally takes too much of BIOGESIC AP ORANGE FLAVOUR SUSPENSION, then consult and inform your doctor immediately or visit the nearby hospital to manage overdose symptoms.

How to administer BIOGESIC AP ORANGE FLAVOUR SUSPENSION in child?

Administer BIOGESIC AP ORANGE FLAVOUR SUSPENSION in child as directed by your physician. Shake well before use. Your doctor will decide the correct dose and duration for your child depending upon the age, body weight and disease condition.

REFERENCES

1. KD Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 204, 206.

2. Maurizio de Martino and Alberto Chiarugi. Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. December 2015. [Accessed 12th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676765/

3. Moraceae Pharmaceuticals Pvt. Ltd. Gag-PR suspension. [Accessed 12th October 2022] http://ace.abhitech.com/moraceae/wp-content/uploads/2019/09/Gag-PR-susp.jpg

4. The Boots Company. Electronic Medicines Compendium (EMC). [Revised on May 2022] [Accessed 12th October 2022] https://www.medicines.org.uk/emc/files/pil.4590.pdf

5. Abiba Pharmacia Pvt Ltd. ACULUM-P SUSPENSION. [Accessed 12th October 2022] https://www.abibapharmacia.com/product/aculum-p-suspension/

USEFUL DIAGNOSTIC TESTS

• Erythrocyte sedimentation rate (ESR)
• C-reactive protein (CRP)