BIOFF 400mg Tablet 10's

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Ofloxacin 400mg
By Biochem Pharmaceutical Industries Ltd
Prescription Needed
(per unit)
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Drug Information for BIOFF 400mg Tablet 10's

What is BIOFF 400mg Tablet used for?

BIOFF 400mg Tablet tablet/syrup is used for the treatment of bacterial infections of skin, lungs prostate, urinary tract. It is also used to treat pelvic inflammatory disease and gonorrhoea.

BIOFF 400mg Tablet eye drops/eye ointment are used for the treatment of bacterial infections of eyes and ulcers in the cornea of the eye.

BIOFF 400mg Tablet injection is used for the treatment of cystitis, urethritis, bronchitis, pneumonia, gonococcal infections and certain types of diarrhoea.

BIOFF 400mg Tablet may also be prescribed for other conditions as determined by the doctor.

How does BIOFF 400mg Tablet work?

BIOFF 400mg Tablet belongs to the class of drugs called broad-spectrum antibiotics. This drug acts by blocking certain bacterial enzymes and inhibiting their function. Thus, it helps in inhibiting the bacterial cell division and propagation. 

How to use BIOFF 400mg Tablet?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Use BIOFF 400mg Tablet as prescribed by your doctor.

  • Swallow the tablet Do not crush or chew the tablet. Take BIOFF 400mg Tablet tablets with or without food.
  • Shake the syrup well before taking each dose to ensure the uniform mixing of the drug.
  • Instil BIOFF 400mg Tablet eye drops into the conjunctival sac of the eye. Do not allow the container tip to touch the eye or its surrounding tissue.
  • Pull the lower eyelid gently and squeeze a thin strip of BIOFF 400mg Tablet eye ointment in the eye. Keep the eyes closed for 1 to 2 minutes after application.
  • BIOFF 400mg Tablet injection should be administered only under the medical supervision.

If you miss a dose of BIOFF 400mg Tablet, use it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for the missed dose.

The overdose symptoms of ofloxacin include the following:

  • Severe Dizziness

You must seek immediate medical care if you experience the above symptom.

What are the drugs that interact with BIOFF 400mg Tablet?

Drugs that interact with BIOFF 400mg Tablet include the following:                                                         

  • Amiodarone
  • Anisindione
  • Bupropion
  • Cisapride
  • Clozapine
  • Dolasetron
  • Efavirenz
  • Hydrocortisone
  • Metrizamide
  • Mifepristone
  • Quinidine
  • Saquinavir
  • Warfarin
  • Ziprasidone

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of BIOFF 400mg Tablet?

The following are the most common side effects of BIOFF 400mg Tablet oral :

  • Nausea
  • Diarrhoea
  • Vomiting
  • Stomach upset
  • Headache
  • Dizziness
  • Trouble sleeping
  • Lightheadedness
  • Dark coloured urine
  • Persistent fever
  • Fainting
  • Irregular heartbeat
  • Unsteadiness
  • Hearing impairment

The following are the most common side effects of BIOFF 400mg Tablet eye drops/eye ointment:

  • Temporary blurred vision
  • Eye discomfort
  • Itching
  • Eye dryness
  • Redness of eye
  • Increased tears
  • Eye pain
  • Swelling of eyes
  • Dizziness
  • Rash

The following are the most common side effects of BIOFF 400mg Tablet injection:

  • Abdominal pain
  • Black/tarry stools
  • Diarrhoea
  • Confusion
  • Anxiety
  • Fever
  • Painful urination
  • Joint pain
  • Bloating
  • Decreased appetite
  • Taste impairment

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while using BIOFF 400mg Tablet?

  • Avoid using the medicine if you are allergic to BIOFF 400mg Tablet or similar drugs.
  • Do not drive or operate heavy machinery if BIOFF 400mg Tablet causes dizziness or blurred vision.
  • Avoid BIOFF 400mg Tablet during pregnancy or breastfeeding because the safe use of the drug is not yet established.
  • Do not stop using the medication abruptly unless instructed by the doctor. Stopping the medication suddenly may cause the illness to return.
  • Do not exceed the dose more than what is prescribed.
  • Use a measuring cup while taking each dose.
  • Keep the medication out of reach of children.
  • Avoid using BIOFF 400mg Tablet if you are having any history of tendonitis or joint pains.

You are advised not to use BIOFF 400mg Tablet if:

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before using BIOFF 400mg Tablet?

  • Tell your doctor if you have any history of myasthenia gravis, heart rhythm disorders, nerve problems, tendon abnormalities, low potassium or magnesium levels.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Notify your doctor if you are pregnant or breastfeeding.

Frequently Asked questions about BIOFF 400mg Tablet

  1. How should BIOFF 400mg Tablet tablet be stored?
  2. BIOFF 400mg Tablet tablets should be stored at room temperature (15 – 30OC) away from light, heat, and moisture.

  3. Should I follow any special dietary instructions while using BIOFF 400mg Tablet?
  4. Yes, it is advised to take plenty of water or fluids while on BIOFF 400mg Tablet medication.

  5. What are the contraindications of BIOFF 400mg Tablet?
  6. BIOFF 400mg Tablet is contraindicated in patients with Myasthenia Gravis, tendonitis and severe joint pains.

  7. Can I use BIOFF 400mg Tablet eye drops to treat viral conjunctivitis?
  8. No, BIOFF 400mg Tablet is only used to treat bacterial infections. Therefore, please consult your doctor for an appropriate medication in case of viral conjunctivitis.

  9. Should I be monitored for any laboratory parameters while using BIOFF 400mg Tablet?
  10. Yes, it is advised to monitor for blood sugar levels and complete blood picture regularly while using BIOFF 400mg Tablet.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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