INTRODUCTION

BIO VISEON 14MG INJECTION contains Sodium Hyaluronate which belongs to the group of medicines called Musculo-skeletal agents. It is used to treat pain in osteoarthritis of the knee. Osteoarthritis is a type of arthritis that occurs when flexible tissue at the ends of bones wears down.

BIO VISEON 14MG INJECTION is not recommended for use in patients with infection of the knee joint, infection and diseases of the skin at the injection site and systemic bleeding disorders. Before receiving BIO VISEON 14MG INJECTION, inform your doctor if you have severe inflammation of the knee, lymphatic or venous stasis (in the leg to be injected) and chondrocalcinosis (mineralization of hyaline cartilage).

If you are pregnant, planning to get pregnant or breast-feeding women, consult your doctor for advice before receiving BIO VISEON 14MG INJECTION.

It should be used with caution in elderly patients. Consult your doctor before receiving BIO VISEON 14MG INJECTION.

The most common side effects of BIO VISEON 14MG INJECTION are joint pain or inflammation, injection site pain and joint effusion. Consult your doctor if any of the side effects worsen.

USES OF BIO VISEON 14MG INJECTION

• Treats pain in osteoarthritis of the knee

HOW BIO VISEON 14MG INJECTION WORKS

BIO VISEON 14MG INJECTION supports tendon and bone regeneration by improving oxygen and nutrient supply to the joints. In osteoarthritis, the joints lack nutrition and become inflamed. BIO VISEON 14MG INJECTION contains hyaluronic acid that acts as a nutritional supplement and helps to reduce inflammation and degradation of joints.

DIRECTIONS FOR USE

BIO VISEON 14MG INJECTION is administered by a doctor or a nurse directly into the knee joint. Your doctor will decide the correct dose, duration of BIO VISEON 14MG INJECTION for you depending upon your age and disease condition.

SIDE EFFECTS OF BIO VISEON 14MG INJECTION

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Inform your doctor if the symptom does not improve.

Skin rash:

Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin. Inform your doctor if the symptoms worsen.

Dizziness:

Lie down until dizziness passes away and then move slowly and carefully. Take plenty amount of rest and drink plenty of fluids. Consult your doctor if the symptoms worsen.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions:

Before receiving BIO VISEON 14MG INJECTION, inform your doctor if you are using any of the following medicines:

• skin disinfectants containing quaternary ammonium salts and compounds
• chlorhexidine (skin preparation agents)

Overdosage:

BIO VISEON 14MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms after receiving BIO VISEON 14MG INJECTION.

SYNOPSIS

MORE INFORMATION

• Store at room temperature

FAQs ABOUT BIO VISEON 14MG INJECTION

What is BIO VISEON 14MG INJECTION used for?

BIO VISEON 14MG INJECTION contains Sodium Hyaluronate, which is used in the treatment of pain in osteoarthritis of the knee. Osteoarthritis is wearing down of the protective tissue at the ends of bones (cartilage), occurs gradually and worsens over time. Joint pain in the hands, neck, lower back, knees or hips is the most common symptom.

For how long should I receive BIO VISEON 14MG INJECTION?

Your doctor might advise you on how long you should continue to receive BIO VISEON 14MG INJECTION. You will need to consult your doctor from time to time to review your treatment and assess your symptoms.

How does BIO VISEON 14MG INJECTION work?

BIO VISEON 14MG INJECTION supports tendon and bone regeneration by improving oxygen and nutrient supply to the joints. In osteoarthritis, the joints lack nutrition and become inflamed. BIO VISEON 14MG INJECTION contains hyaluronic acid that acts as a nutritional supplement and helps to reduce inflammation and degradation of joints.

What are the common side effects of BIO VISEON 14MG INJECTION?

The most common side effects of receiving BIO VISEON 14MG INJECTION are joint pain or inflammation, injection site pain, joint effusion and joints disease (arthropathy). Consult your doctor if any of the side effects worsen.

How is BIO VISEON 14MG INJECTION administered?

BIO VISEON 14MG INJECTION is administered by a doctor or a nurse directly into the knee joint. Your doctor will decide the correct dose, duration of BIO VISEON 14MG INJECTION for you depending upon your age and disease condition.

REFERENCES

1. KD. Tripathi. Section 3, Antirheumatic and Antigout Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page –210 -218.

2. Huang TL, Chang CC, Lee CH, Chen SC, Lai CH, Tsai CL. Intra-articular injections of sodium hyaluronate (Hyalgan) in osteoarthritis of the knee. a randomized, controlled, double-blind, multicenter trial in the Asian population. NIH. National Library of Medicine, National center for biotechnology information. October 2011. [Accessed on 20th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203101/

3. Guarda-Nardini, L., Masiero, S. and Marioni, G., 2005. Conservative treatment of temporomandibular joint osteoarthrosis: intra-articular injection of sodium hyaluronate. Journal of Oral Rehabilitation. September 2005. [Accessed on 20th September 2022] https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2842.2005.01505.x

4. Genzyme Biosurgery. Synvisc One. [Revised in September 2014] [Accessed on 20th September 2022] https://products.sanofi.us/synviscone/synviscone.pdf

5. Fidia Farmaceutici S.p.A. Hyalgan. Health Products Regulatory Authority (HPRA). [Revised in December 2009] [Accessed on 20th September 2022] https://www.hpra.ie/img/uploaded/swedocuments/LicenseSPC_PA0814-001-001_05042016103037.pdf

6. Hanmi Pharm Co. Ltd. Synojoynt. U.S. Food & Drug Administration. [Accessed on 20th September 2022] https://www.accessdata.fda.gov/cdrh_docs/pdf17/P170016D.pdf

7. Anika Therapeutics, Inc. Monovisc. [Accessed on 20th September 2022] http://synthes.vo.llnwd.net/o16/LLNWMB8/IFUs/US/Monovisc-US-IFU_Word.pdf