INTRODUCTION

BENIFOR contain Benidipine hydrochloride which belongs to a group of medicine called calcium channel blocker. It is used to treat hypertension, renal parenchymal hypertension, and angina pectoris. Hypertension is a condition in which the force of the blood against the artery wall is too high. High blood pressure often has no symptoms. Over time, if untreated, it can cause health condition such as heart disease and stroke.

Renal parenchymal hypertension is a form of secondary hypertension caused by kidney diseases. Angina pectoris is the medical term for chest pain or discomfort due to coronary heart diseases. It occurs when the heart muscle does not get as much blood as it needs. This usually happens because one or more of the heart arteries is narrowed or blocked. It is also called ischemia.

BENIFOR works by blocking calcium inflow into cells and consequently dilates constricted vessels to decrease blood pressure. It also dilates coronary arteries of the heart to prevent developing anginal attack. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF BENIFOR

• Treat hypertension, renal parenchymal hypertension, and angina pectoris

HOW BENIFOR WORKS

BENIFOR works by blocking calcium inflow into cells and consequently dilates constricted blood vessels to decrease blood pressure. It also dilates coronary arteries of the heart to prevent developing anginal attack.

DIRECTIONS FOR USE

Always take BENIFOR exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine. Do not take grapefruit juice while taking this medicine.

SIDE EFFECTS OF BENIFOR

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor about all the medicines you use, including prescription and non-prescription medicines, and herbal supplements.

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT BENIFOR

Is BENIFOR safe for a long time?

It is safe if used in the dose and duration directed by your doctor.

Is safe to drive or operate heavy machinery while taking BENIFOR?

No, do not drive or operate any machine while taking this medicine as it may cause dizziness or lightheadedness.

Does alcohol interfere with working of BENIFOR?

Yes, consumption of alcohol is not recommended during treatment with this medicine.

REFERENCES

1. KD Tripathi. Antianginal and Other Anti-ischaemic Drugs. Essentials of Medical Pharmacology. Seventh Edition,2013. Page - 550-552.

2. Kensuke Io 1, Shinya Minatoguchi, Kazuhiko Nishigaki, Shinsuke Ojio, Tsutomu Tanaka, Tomonori Segawa, Hitoshi Matsuo, Sachiro Watanabe, Arihiro Hattori, Katsumi Ueno, Hiroyoshi Ono, Kunihiko Hiei, Hironobu Sato, Norihiko Morita, Toshiyuki Noda, Toshihiko Kato, Masanori Kawasaki, Genzou Takemura, Hisayoshi Fujiwara. Effects of benidipine and some other calcium channel blockers on the prognosis of patients with vasospastic angina. Cohort study with evaluation of the ergonovine coronary spasm induction test. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov.2007. [Accessed 11 Dec 2020] https://pubmed.ncbi.nlm.nih.gov/17966756/

3. TOWA PHARMACEUTICAL CO., LTD, Jun 2013 [Accessed 11 Dec 2020] https://www.rad-ar.or.jp/siori/english/kekka.cgi?n=34089#:~:text=This%20medicine%20blocks%20calcium%20inflow,parenchymal%20hypertension%20and%20angina%20pectoris.

4. OHARA Pharmaceutical Co., Ltd, Jul 2008 [Accessed 11 Dec 2020] https://www.ohara-ch.co.jp/appendix/pdf/inc03/benidipineHydrochloride8T-SIE.pdf

USEFUL DIAGNOSTIC TESTS

• Kidney function test