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INTRODUCTION
BACSTOL 100MG contains Trimethoprim which belongs to the group of medicines called Antibiotics. It is used to treat bacterial infections of the urinary tract and the respiratory tract. It can also be used to prevent recurrent urinary tract infections.
Trimethoprim is a potent antibacterial agent. It kills the susceptible bacteria by preventing the production of certain substances (folic acid) within the bacterial cell which is required for its growth and survival.
Take the full course of BACSTOL 100MG without any interruption. Before taking BACSTOL 100MG, inform your doctor if you have any problems in your kidneys. You must also inform your doctor if you have folic acid deficiency, porphyria (inherited blood disorder) or uncontrollable diabetes before taking BACSTOL 100MG as a precaution.
BACSTOL 100MG is not recommended for use in patients with serious liver problems or anemia. It is also not suitable for use in women who are pregnant or breastfeeding and in children (aged below 6 years, including infants aged below 4 months).
BACSTOL 100MG may cause anemia or hyperkalemia (high blood potassium levels) in some individuals. To avoid this, your doctor will periodically monitor your RBC count and blood potassium levels as a precaution.
Other most common side effects of taking BACSTOL 100MG are headache, skin rashes, thrush, nausea, vomiting and diarrhea. Contact your doctor if any of these side effect worsens.
USES OF BACSTOL 100MG
- Treats bacterial infections of the urinary tract and respiratory tract
- Prevents recurrent urinary tract infections
HOW BACSTOL 100MG WORKS
BACSTOL 100MG is an antifolate antibacterial agent. It kills the susceptible bacteria by blocking the actions of an enzyme called dihydrofolate reductase which is essential for the formation of certain substances (folic acid) in the bacterial cell that gives them energy for growth and multiplication. As a result, it stops the bacteria from growing, and prevents the infection from spreading.
DIRECTIONS FOR USE
Take BACSTOL 100MG as advised by your physician. Swallow the medicine with glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.
It is important to take the full course of BACSTOL 100MG without any interruption. Therefore, do not miss a dose or stop taking BACSTOL 100MG without consulting your doctor as it may lead to growth of harmful bacteria within the body which cannot be further controlled by BACSTOL 100MG.
SIDE EFFECTS OF BACSTOL 100MG
COMMON
- high blood potassium levels (causing muscle cramps, irregular heart rhythm, headache, nausea, dizziness or diarrhea)
- headache
- skin rashes, hives
- thrush
- nausea, vomiting
- diarrhea
RARE
Stop taking BACSTOL 100MG and contact your doctor immediately if you experience any of the following side effects such as:
- serious allergic reactions (such as skin eruptions/lesions, deep swelling of the skin, swelling of the face, lips, tongue and throat and difficulty in breathing)
- chest pain
- shock or fainting
- severe blistering/peeling of the skin
- pancreatitis (signs may include a sudden, severe upper abdominal pain)
- jaundice (yellowing of the skin or whites of the eyes)
HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume alcohol. Consult your doctor if your headache worsens.
Nausea and Vomiting:
Take BACSTOL 100MG with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
Diarrhea:
Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-treat diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.
WARNING & PRECAUTIONS
PREGNANCY
BACSTOL 100MG is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
BREASTFEEDING
BACSTOL 100MG is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
BACSTOL 100MG does not affect your ability to drive or operate any heavy tools or machinery. However, if you experience any unpleasant symptoms after taking BACSTOL 100MG, do not drive or operate heavy tools or machinery.
KIDNEY
BACSTOL 100MG should be used with caution in patients with kidney problems (such as dialysis). Therefore, consult your doctor before taking it.
LIVER
BACSTOL 100MG is not recommended for use in patients with severe liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take BACSTOL 100MG if you are allergic to Trimethoprim.
OTHERS
BACSTOL 100MG is not recommended for use if you:
- suffer from any blood disorders such as anaemia
Before taking BACSTOL 100MG, inform your doctor if you:
- have folic acid deficiency
- have hyperkalemia (high blood potassium levels)
- have porphyria (an inherited blood disorder)
Use in pediatrics:
BACSTOL 100MG is not recommended for use in premature babies and in infants aged below 4 months. It is also not suitable for use in children (aged below 6 years). Therefore, consult your doctor before taking it.
Use in geriatrics:
BACSTOL 100MG should be used with caution in elderly patients (aged 65 years or older). Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug Interaction:
Before taking BACSTOL 100MG, inform your doctor if you are taking any of the following:
- repaglinide (a medicine used to treat diabetes)
- procainamide, digoxin (medicines used to treat abnormal heart rhythm)
- potassium supplements
- medicines used to treat high blood pressure such as ACE inhibitors (Ex. captopril, enalapril) or angiotensin II antagonists (Ex. losartan, valsartan)
- heparin, warfarin (used to treat blood clots)
- potassium-sparging diuretics (used to treat edema) Ex. spironolactone, eplerenone, amiloride or triamterene
- rifampicin (a medicine used to treat tuberculosis)
- pyrimethamine (a medicine used to treat parasite infection)
- dapsone (a medicine used to leprosy)
- immunosuppressant drugs (used to suppress immune function) Ex. methotrexate, azathioprine or ciclosporin
- medicines that can cause bone marrow suppression
Overdosage:
If you or anyone else accidentally took more BACSTOL 100MG, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Trimethoprim |
| Pharmacological Category | : | Anti-folate antibiotic |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep BACSTOL 100MG out of reach of children
- Store BACSTOL 100MG at room temperature
FAQs ABOUT BACSTOL 100MG
How long will it take for BACSTOL 100MG to show the results?
BACSTOL 100MG generally starts working within 24 hours following ingestion. It may take around 3-6 days for you to notice a difference from your condition. However, it may take a few weeks for BACSTOL 100MG to reduce the infection completely. Therefore take BACSTOL 100MG consistently as instructed by your doctor without any interruption.
Can BACSTOL 100MG cause diarrhea?
Yes. BACSTOL 100MG may cause diarrhea in some individuals. Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. However, if you experience any bloody diarrhea with severe stomach pain contact your doctor immediately.
What should I do if I forget to take a dose of BACSTOL 100MG?
If you miss a dose of BACSTOL 100MG take it as soon as you remember. However, if it is time to take to next dose, skip the missed dose and take the next one at regular time. Do not take a double dose of BACSTOL 100MG to make up for the missed dose.
What if I don't get better after using BACSTOL 100MG?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Is BACSTOL 100MG an antibiotic?
Yes, BACSTOL 100MG is an antibiotic. It kills the susceptible bacteria by preventing the production of certain substances (folic acid) within the bacterial cell which is required for its growth and survival.
Can I stop taking BACSTOL 100MG once my symptoms subside?
No. It is important to take the full course of BACSTOL 100MG without any interruption. Do not miss a dose or stop taking BACSTOL 100MG without consulting your doctor as it may lead to growth of harmful bacteria within the body which cannot be further controlled by BACSTOL 100MG.
Will taking a higher dose of BACSTOL 100MG be more effective?
No. Taking a higher dose of BACSTOL 100MG can do more harm rather than being beneficial. Always take the dose prescribed by your physician. Your doctor will decide the suitable dose for you depending upon your age, body weight and severity of the infection.
REFERENCES
1. K.D. Tripathi, Antimicrobial Drugs: General Considerations, Essentials of medical pharmacology. Seventh edition. 2013, Page 689.
2. Elizabeth Crellin, Kathryn E Mansfield, Clémence Leyrat, Dorothea Nitsch, Ian J Douglas, Adrian Root, Elizabeth Williamson, Liam Smeeth, Laurie A Tomlinson. Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study. NIH: National Library of Medicine, National Center for Biotechnology Information. PubMed. 9 February 2018. [Accessed on 9th June 2022] https://pubmed.ncbi.nlm.nih.gov/29438980/
3. Accord. Electronic Medicines Compendium (EMC). [Revised in November 2019] [Accessed on 9th June 2022] https://www.medicines.org.uk/emc/files/pil.5925.pdf
USEFUL DIAGNOSTIC TESTS
- Complete Blood count
PRODUCT DETAILS
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