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AZRO 500mg Tablet 5's
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INTRODUCTION
AZRO 500MG TABLET contains Azithromycin which belongs to the group of medicines called Macrolide antibiotics. It is used to treat mild to moderate susceptible infections caused by bacteria and other micro-organisms which includes chest, throat, nasal infections such as bronchitis, pneumonia, tonsillitis, sore throat and sinusitis.
It is also used to treat ear infections and skin & soft tissue infections (such as an abscess/boil) in affected individuals which is also indicated for use to treat sexually transmitted diseases such as cervicitis (caused by organisms such as Chlamydia trachomatis/ Neisseria gonorrhoea) in affected individuals.
AZRO 500MG TABLET is not recommended for use in patients allergic to azithromycin, other antibiotics such as erythromycin/clarithromycin (macrolides), and ketolides. It is also not recommended for use in patients with a history of cholestatic jaundice/hepatic dysfunction.
Before taking AZRO 500MG TABLET, inform your doctor if you have diabetes, myasthenia gravis (condition marked by weak muscles), heart problems, and/or kidney problems.
AZRO 500MG TABLET should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. It is also advised to be used with caution in breast-feeding woman as it is unknown whether the medicine gets excreted in the breast milk.
AZRO 500MG TABLET is not recommended for use in children weighing less than 45 kgs which is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.
The most common side effects of taking AZRO 500MG TABLET are stomach cramps, nausea, vomiting, diarrhoea, flatulence, dizziness, headache, and/or skin rash. Consult your doctor if any of the symptoms worsen.
USES OF AZRO 500MG TABLET
- Treats mild to moderate susceptible infections caused by bacteria and other micro-organisms which includes chest, throat, nasal infections (such as bronchitis, pneumonia, tonsillitis, sore throat and sinusitis)
- Treats ear infections and skin & soft tissue infections (such as an abscess/boil) in affected individuals
- Treats sexually transmitted diseases such as cervicitis (caused by organisms such as Chlamydia trachomatis/ Neisseria gonorrhea) in affected individuals
HOW AZRO 500MG TABLET WORKS
AZRO 500MG TABLET works by inhibiting bacterial protein synthesis (essential for the bacteria to growth) that results in its destruction thus preventing its growth and spread of infection in affected individuals.
DIRECTIONS FOR USE
Tablet:
Take AZRO 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF AZRO 500MG TABLET
COMMON
- stomach cramps, nausea, vomiting, diarrhoea, flatulence
- dizziness, headache
- numbness/pickling sensation
- loss of appetite, taste disturbance
- visual disturbances, deafness
- skin rash, itching
- joint pain
- tiredness, weakness
UNCOMMON
- yeast infections of the mouth and vagina
- allergic reactions of varying severity
- increased skin sensitivity to sunlight
- feeling nervous
- reduced sense of touch or sensation
- sleepiness/sleeplessness
- poor hearing/ringing in the ears
- racing heartbeat, chest pain
- constipation, fever
- signs of inflammation of the liver such as jaundice (yellowing of skin and whites of eyes), loss of appetite, dark urine
- general loss of strength
- swelling
- general discomfort
RARE
- vertigo (spinning head)
- agitation
Stop taking AZRO 500MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- sudden wheeziness, difficulty in breathing, swelling of eyelids, face/lips, rash, and/or itching (affecting the whole body)
- signs of serious bowel inflammation such as severe/prolonged diarrhoea
- signs of severe allergic skin reactions such as rash (causing redness and flaking of skin), scratch marks, and/or cracked skin
- rapid/irregular heartbeat
- low blood pressure
- angioedema (swelling underneath the skin)
- signs of cholestatic jaundice/hepatic dysfunction such as yellowing of skin and whites of eyes, dark urine
- dizziness, faint/ suffer from muscle weakness
- serious skin reaction such as Stevens-Johnson Syndrome (associated with signs such as blistering of the skin, mouth, eyes and genitals), Toxic epidermal necrosis (associated with signs such as blistering of the skin), Drug reaction with eosinophilia and systemic symptoms (such as small, itchy red bumps), and/or Acute generalized exanthematous pustulosis skin (associated with signs such as skin eruption with rapid appearance of red skin studded with small pustules)
HOW TO MANAGE SIDE EFFECTS
Constipation
Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.
Diarrhea
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult your doctor and inform them if the symptom gets worse.
Headache
If AZRO 500MG TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking AZRO 500MG TABLET. If it lasts more than a week or severe, inform your doctor.
Nausea And Vomiting
Try to take AZRO 500MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets worse.
WARNING & PRECAUTIONS
PREGNANCY
Monitoring requiredAZRO 500MG TABLET should be used with caution during pregnancy and in woman planning for pregnancy only if it is clearly necessary. Consult your doctor before taking the medicine.
BREASTFEEDING
Consult your doctorAZRO 500MG TABLET should be used with caution in breastfeeding woman as it is unknown whether the medicine is excreted in breastmilk. Consult your doctor before taking the medicine.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any machines if AZRO 500MG TABLET affects your ability to drive or operate any machines.
KIDNEY
Use with CautionAZRO 500MG TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice before taking the medicine.
LIVER
Consult your doctorAZRO 500MG TABLET is not recommended for use in patients with a history of cholestatic jaundice/hepatic dysfunction. It should be used with caution in patients with other liver problems. Consult your doctor before taking the medicine.
ALLERGY
ContraindicatedDo not take AZRO 500MG TABLET if you are allergic to azithromycin, other antibiotics such as erythromycin/clarithromycin (macrolides), ketolides, and/or any other ingredients of this medicine.
HEART DISEASE
Use with CautionAZRO 500MG TABLET should be taken with caution in patients with heart problems such as prolongation of QT interval, Torsades de pointes, and other proarrhythmic conditions. Consult your doctor before taking the medicine.
OTHERS
Before taking AZRO 500MG TABLET, inform your doctor if you:
- diabetes
- myasthenia gravis (condition marked by weak muscles)
- intolerance to certain sugars
Use in Pediatrics:
AZRO 500MG TABLET is not recommended for use in children weighing less than 45 kgs. Consult your doctor before taking the medicine.
Use in Geriatrics:
AZRO 500MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking.
INTERACTIONS
A. Drug-Drug interactions:
Before taking AZRO 500MG TABLET, inform your doctor if you are taking any of the following medicine:
- ergotamine (medicine used to treat migraine)
- warfarin (medicine used to prevent blood clots)
- ciclosporin (used to prevent transplanted organ rejection)
- antacids (used to treat indigestion) Ex. aluminium hydroxide, magnesium carbonate
- digoxin (used to treat heart failure)
- colchicine (used for gout and familial Mediterranean fever)
- terfenadine (used for skin allergy)
- hydroxychloroquine, chloroquine (medicines used to treat malaria)
- efavirenz, nelfinavir (medicines used in the treatment of HIV)
- fluconazole (used to treat fungal infection)
Overdosage:
If you or anyone else accidentally take too much of AZRO 500MG TABLET, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Azithromycin |
| Pharmacological Category | : | Macrolide antibiotics |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Capsule, Tablet, Dispersible tablet, Syrup, Dry syrup, Suspension, Oral Suspension, Liquid, Injection, Infusion, Gel, Eye ointment, Eye drops |
MORE INFORMATION
- Keep AZRO 500MG TABLET out of reach of children
- Store AZRO 500MG TABLET at room temperature
FAQs ABOUT AZRO 500MG TABLET
Q. What is AZRO 500MG TABLET used for?
A. AZRO 500MG TABLET is used to treat mild to moderate susceptible infections caused by bacteria and other micro-organisms which includes chest, throat, nasal infections (such as bronchitis, pneumonia, tonsillitis, sore throat and sinusitis). It is also used to treat ear infections and skin & soft tissue infections (such as an abscess/boil) which is also indicated for use to treat sexually transmitted diseases such as cervicitis (caused by organisms such as Chlamydia trachomatis/ Neisseria gonorrhoea) in affected individuals.
Q. How AZRO 500MG TABLET works?
A. AZRO 500MG TABLET works by inhibiting bacterial protein synthesis (essential for the bacteria to growth) that results in its destruction thus preventing its growth and spread of infection in affected individuals.
Q. What are the most common side effects of taking AZRO 500MG TABLET?
A. The most common side effects of taking AZRO 500MG TABLET are stomach cramps, nausea, vomiting, diarrhoea, flatulence, dizziness, headache, and/or skin rash. Consult your doctor if any of the symptoms worsen.
Q. How to take AZRO 500MG TABLET?
A. Take AZRO 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q. Who should avoid taking AZRO 500MG TABLET?
A. AZRO 500MG TABLET is not recommended for use in patients allergic to azithromycin, other antibiotics such as erythromycin/clarithromycin (macrolides), and/or ketolides. It is also not recommended for use in patients suffering from liver diseases such as cholestatic jaundice or hepatic dysfunction.
REFERENCES
1. KD Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics; Urinary Antiseptics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 755.
2. Michael J Parnham , Vesna Erakovic Haber, Evangelos J Giamarellos-Bourboulis, Gianpaolo Perletti , Geert M Verleden, Robin Vos. Azithromycin: mechanisms of action and their relevance for clinical applications. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. August 2014. [Accessed on 6th October 2022] https://pubmed.ncbi.nlm.nih.gov/24631273/
3. John E Stupka, Eric M Mortensen, Antonio Anzueto, and Marcos I Restrepo. Community-acquired pneumonia in elderly patients. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. August 2010. [Accessed on 6th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917114/
4. Haupt Pharma Latina S.r.l. Electronic Medicines Compendium (EMC). [Revised in March 2022]. [Accessed 7th October 2022] https://www.medicines.org.uk/emc/files/pil.1073.pdf
5. Azilide. Micro Labs Ltd. [Accessed 7th October 2022] https://www.microlabsltd.com/elibrary/node/1984
6. Borg Pharmaceutical Ind. NEOZOLID 600 MG TABLETS. [Accessed 7th October 2022] https://www.borg-pharma.com/products/neozolid-600-mg-tablets/
7. Al-Rowad Pharmaceutical Industries. AZIROWA 1 GM FCT. [Accessed 7th October 2022] https://alrowadrpic.com/product/azirowa-1-gm-fct/
USEFUL DIAGNOSTIC TESTS
- Complete blood count
- Bacterial culture test
AUTHOR DETAILS
Written By Dr. K .AZEEM HUSSAIN, B.D.S
Last updated on 30 Jan 2023 | 04:45 PM(IST)
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