ATROCORD F Tablet 10's

INTRODUCTION

ATROCORD F TABLET is a combination of Atorvastatin and Fenofibric Acid which belongs to the group of medicines called Hypolipidemic drugs. It is used to treat hyperlipidemia (high blood lipid levels) in addition to proper diet, exercise and lifestyle changes.

Hyperlipidemia is a condition characterized by increased levels of bad cholesterol and triglycerides (fats) in the blood. If left untreated, these fat particles get deposited in the blood vessels and may obstruct blood flow through them, leading to various complications such as heart attack or stroke.

By reducing lipid levels in the blood, ATROCORD F TABLET can also be used to prevent the risk of heart attack, stroke, atherosclerosis and other circulatory disorders.

Take ATROCORD F TABLET with meals. Along with the treatment, follow the diet, exercise and lifestyle changes instructed by your doctor to achieve better results. Avoid drinking large amount of alcohol while taking ATROCORD F TABLET. If you are diabetic, work on your blood sugar levels and keep them under control.

Before taking ATROCORD F TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have thyroid problems, diabetes, high blood pressure or a family history of muscle disorders.

ATROCORD F TABLET is not recommended for use in patients with severe liver or kidney problems. It is also not suitable for use in patients who had recently taken an antibiotic called Fusidic acid to treat bacterial infections.

Do not take ATROCORD F TABLET if you are pregnant or breastfeeding. Women of childbearing potential must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with ATROCORD F TABLET. If you accidentally become pregnant while taking ATROCORD F TABLET, stop taking this medicine and consult your doctor immediately.

During treatment with ATROCORD F TABLET, your doctor will periodically monitor your liver functions, kidney functions, blood sugar levels, muscle functions and blood cholesterol levels to avoid the risk of unwanted side effects.

The most common side effects of taking ATROCORD F TABLET are headache, constipation, bloating, muscle pain, neck pain, inflammation of the nose, throat pain and liver problems. Consult your doctor if they bother you.

You must also inform your doctor if you experience severe unexplained muscle pain or weakness with fever, weakness or reddish-brown urine after taking ATROCORD F TABLET.

USES OF ATROCORD F TABLET

It is used to:

• Treat high blood cholesterol levels
• Prevent the risk of heart attack, stroke or atherosclerosis

HOW ATROCORD F TABLET WORKS

ATROCORD F TABLET is a lipid-lowering medicine. It reduces the levels of bad cholesterol (VLDL and LDL) and triglycerides in the body by modulating the actions of certain enzymes that are involved in lipid metabolism (such as HMG-CoA reductase and lipoprotein lipase). Additionally, it can also reduce the amount of cholesterol absorbed in the body.

By lowering the blood lipid levels, ATROCORD F TABLET prevents fat deposition within the blood vessels and reduces the chances of heart attack, stroke, atherosclerosis or other circulatory problems.

DIRECTIONS FOR USE

Take ATROCORD F TABLET as directed by your physician. It is taken preferably after meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking ATROCORD F TABLET without consulting your doctor.

SIDE EFFECTS OF ATROCORD F TABLET

HOW TO MANAGE SIDE EFFECTS

Constipation

Eat plenty of fiber-rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea And Vomiting

Take ATROCORD F TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

WARNING & PRECAUTIONS

PREGNANCY

Contraindicated

ATROCORD F TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking ATROCORD F TABLET if you are pregnant, think you may be pregnant or planning to have a baby. If you accidentally become pregnant while undergoing therapy with ATROCORD F TABLET, inform your doctor immediately. Women of childbearing potential must use suitable contraception to avoid pregnancy while undergoing therapy with ATROCORD F TABLET.

BREASTFEEDING

Contraindicated

ATROCORD F TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any heavy tools or machines if your ability is affected by ATROCORD F TABLET.

ALCOHOL

Consult your doctor

Avoid consumption of alcohol while taking ATROCORD F TABLET as it may reduce the effectiveness of this medicine.

KIDNEY

Consult your doctor

ATROCORD F TABLET is not recommended for use in patients with moderate to severe kidney problems. It should be used with caution in patients with other mild kidney problems. Therefore, consult your doctor before taking it.

LIVER

Consult your doctor

ATROCORD F TABLET is not recommended for use in patients with severe liver or gall bladder problems. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it

ALLERGY

Contraindicated

Do not take ATROCORD F TABLET if you are allergic to Atorvastatin or Fenofibric Acid.

LUNGS

Use with Caution

ATROCORD F TABLET should be used with caution in patients with respiratory failure. Therefore, consult your doctor before taking it.

USE IN PEDIATRICS

Contraindicated

ATROCORD F TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice.

USE IN GERIATRICS

Use with Caution

ATROCORD F TABLET should be used with caution in elderly patients (aged 70 years or above). Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking ATROCORD F TABLET inform to your doctor if you are taking any of the following medicines such as:

• medicines used to suppress immune system after organ transplantation (Ex. cyclosporin)
• medicines used for blood thinning (Ex. warfarin, acenocoumarol)
• clopidogrel (a medicine used to treat blood clots)
• medicines used to treat bacterial infections (Ex. erythromycin, Fusidic acid, clarithromycin, telithromycin)
• medicines used to treat HIV infection (Ex. indinavir, darunavir, ritonavir, dasabuvir, sofosbuvir, velpatasvir, voxilaprevir, lopinavir, atazanavir, combination of tipranavir/ritonavir etc.)
• medicines used to treat hepatitis C infection (such as telaprevir, boceprevir and the combination of elbasvir/grazoprevir, ledipasvir/sofosbuvir)
• medicines used for contraception (Ex. ethinylestradiol)
• medicines used to treat diabetes (Ex. rosiglitazone, pioglitazone)
• other medicines used to treat high lipid levels in blood (Ex. gemfibrozil, cholestyramine, colesevelam, ezetimibe)
• medicines used to treat heart problems (such as amlodipine, nifedipine, digoxin, verapamil, amiodarone)
• medicines used to treat fungal infections (Ex. ketoconazole, itraconazole, voriconazole, fluconazole, posaconazole)
• letemovir (a medicine used to treat cytomegalovirus infection)
• St. John’s Wart (a medicine used to treat depression)
• medicines used to treat gout (Ex. colchicine)
• medicines used for indigestion such as antacids (Ex. aluminium hydroxide)
• rifampicin (a medicine used to treat tuberculosis)
• cimetidine (a medicine used to treat stomach ulcers)
• stiripentol (a medicine used to treat epilepsy)
• phenazone (a medicine used for pain relief)

B. Drug- Food Interactions:

Avoid drinking grapefruit juice while taking ATROCORD F TABLET as it may increase the risk of side effects.

Overdosage:

If you or anyone else accidentally took more ATROCORD F TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep ATROCORD F TABLET out of reach of children
• Store ATROCORD F TABLET at room temperature

FAQs ABOUT ATROCORD F TABLET

Q: What are the uses of ATROCORD F TABLET?

A: ATROCORD F TABLET is a lipid-lowering medicine. It is used to control elevated blood cholesterol levels in addition to proper diet, exercise and lifestyle changes. By reducing lipid levels in the blood, ATROCORD F TABLET can also be used to prevent the risk of heart attack, stroke, atherosclerosis and other circulatory disorders.

Q: Can the use of ATROCORD F TABLET cause diabetes?

A: ATROCORD F TABLET may increase blood sugar levels in some patients. This is most predominantly seen in patients who already have diabetes along with obesity and/or hypertension. Therefore, consult your doctor before taking this medicine if you are diabetic, obese or have hypertension. Your doctor will closely monitor your blood sugar levels while undergoing therapy with ATROCORD F TABLET to avoid any unwanted side effects.

Q: What is the best time to take ATROCORD F TABLET?

A: Take ATROCORD F TABLET as advised by your physician. Your doctor will decide the best time for you to take ATROCORD F TABLET. Try to take ATROCORD F TABLET at the same time each day. It is preferably taken with meals.

Q: What are the side effects of taking ATROCORD F TABLET?

A: The most common side effects of taking ATROCORD F TABLET are headache, constipation, bloating, muscle pain, neck pain, inflammation of the nose, throat pain and liver problems. Consult your doctor if they bother you. Also, inform your doctor if you experience severe unexplained muscle pain, tenderness, or weakness along with fever after taking this medicine.

Q: Can I consume alcohol along with ATROCORD F TABLET?

A: ATROCORD F TABLET is not recommended for use in patients who consume large amounts of alcohol. It is advisable to avoid alcohol consumption while taking ATROCORD F TABLET to achieve maximum benefits.

Q: Can the use of ATROCORD F TABLET make me feel more tired?

A: Yes. The use of ATROCORD F TABLET can make you feel more tired because it acts by reducing the supply of energy to the muscles present in your body. However, you may also feel tired due to other reasons such as severe liver damage. Consult your doctor if you experience excessive tiredness with muscle pain.

Q: Who should not take ATROCORD F TABLET?

A: ATROCORD F TABLET is not recommended for use in patients with severe liver or kidney problems. It is also not suitable for use in patients having muscle problems or inflammation of the pancreas. If you are pregnant or breastfeeding consult your doctor before taking ATROCORD F TABLET. Before taking ATROCORD F TABLET inform your doctor if you have diabetes or any heart problems. Do not take this medicine if you are undergoing therapy with antibiotics such as fusidic acid.

Q: What are the dietary restrictions that I need to follow while taking ATROCORD F TABLET?

A: While taking ATROCORD F TABLET, follow a low-cholesterol diet as instructed by your doctor and avoid excessive alcohol intake. Avoid eating oil-rich or deep-fried foods. Limit your sugar intake by avoiding eating biscuits, cakes, soft drinks or pastries. Stick to a simple nutritious diet.

Q: What should I do if I forget to take a dose of ATROCORD F TABLET?

A: If you forget to take a dose of ATROCORD F TABLET, take it as soon as you remember. However, if it is time to take the next dose of ATROCORD F TABLET, skip the missed dose and take the next one at regular times. Do not take a double dose of ATROCORD F TABLET to compensate for the missed dose, as it could lead to toxicity.

Q: Can I stop taking ATROCORD F TABLET once my blood cholesterol level is controlled?

A: Do not stop taking this medicine without consulting your doctor, as it could once again increase your blood cholesterol levels. ATROCORD F TABLET can only control your blood cholesterol levels and cannot cure them completely, therefore, it is important to take this medicine until your doctor advises you to stop.

Q: Can I take ATROCORD F TABLET if I am diabetic?

A: ATROCORD F TABLET may increase blood sugar levels in some patients. This is most predominantly seen in patients who already have diabetes along with obesity and/or hypertension. Therefore, consult your doctor before taking ATROCORD F TABLET if you are diabetic.

Q: Does ATROCORD F TABLET cause muscle pain?

A: ATROCORD F TABLET may cause a rare but serious side effect of unexplained muscle pain or weakness called rhabdomyolysis. It might be an early sign of a potentially serious muscle degradation. Therefore, consult your doctor if you experience any signs of muscle problems after taking ATROCORD F TABLET. Also, talk to your doctor before taking ATROCORD F TABLET if you already have weak muscles or have a family history of any muscle disorders.

Q: What is ATROCORD F TABLET and what does it do?

A: ATROCORD F TABLET is a lipid-lowering medicine. It reduces the levels of bad cholesterol (VLDL and LDL) and triglycerides in the body by modulating the actions of certain enzymes that are involved in lipid metabolism (such as HMG-CoA reductase and lipoprotein lipase). Additionally, it can also reduce the amount of cholesterol absorbed in the body and reduces the chances of heart attack, stroke, atherosclerosis or other circulatory problems.

Q: How long should I take ATROCORD F TABLET to treat high cholesterol?

A: You should take ATROCORD F TABLET as long as your doctor advises you to take it. Because ATROCORD F TABLET will only help you in managing your cholesterol levels and cannot completely cure them. If you stop using ATROCORD F TABLET, your cholesterol levels may raise once again.

Q: Can ATROCORD F TABLET be taken by pregnant or breastfeeding women?

A: ATROCORD F TABLET is not recommended for use in pregnant or breastfeeding women. Therefore, consult your doctor before taking it. Women of childbearing age must use a reliable contraceptive method to avoid pregnancy while undergoing therapy with this medicine. However, if you accidentally become pregnant while taking this medicine, stop taking it and consult your doctor immediately.

REFERENCES

1. KD. Tripathi. Hypolipidemic Drugs and Plasma Expanders. Essentials of medical pharmacology. Seventh edition. Page - 637 & 639.

2. Gursharan Sidhu; Jayson Tripp. Fenofibrate. StatPearls [Internet]. NIH. National Library of Medicine. National Center for Biotechnology Information. March 2022. [Accessed on 14th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK559219/

3. Harold E. Bays, Peter H. Jones, Syed M. Mohiuddin, Maureen T. Kelly, Hsiaoming Sun Carolyn M. Setze, Susan M. Buttler, Darryl J. Sleep, James C. Stolzenbach.  Long-term safety and efficacy of fenofibric acid in combination with statin therapy for the treatment of patients with mixed dyslipidemia. Journal of Clinical Lipidology. ScienceDirect.com. December 2008. [Accessed on 14th October 2022] https://www.sciencedirect.com/science/article/abs/pii/S1933287408008878

4. Sun Pharmaceutical Industries Europe B.V. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 14th October 2022]. https://www.medicines.org.uk/emc/files/pil.4339.pdf

5. Abbott Laboratories. Fenofibric Acid. U.S. Food and Drug Administration. [Revised in September 2010] [Accessed on 13th October 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022224s003lbl.pdf

6. Palmetto Pharmaceuticals, Inc. Fenofibric Acid – Tablet. [Revised in December 2020] [Accessed on 13th October 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=bb559b34-79b1-45a6-a148-38639115cd49&type=display

USEFUL DIAGNOSTIC TESTS

• Cholesterol - HDL
• Cholesterol - LDL
• Cholesterol - Total

AUTHOR DETAILS

Written By Srilekha. R, B.Pharm
Last updated on 15 Mar 2023 | 03:50 PM(IST)