ATRANZA 10MG contains Tretinoin which belongs to the group of medicines called retinoids. It is used to treat a type of blood disorder called as acute promyelocytic leukemia (APL). APL is form of acute myeloid leukemia (bone marrow cancer), in which the immature blood-forming cells (RBC, WBC and platelets) called promyelocytes accumulates in the bone marrow and blood, leading to shortage of normal white and red blood cells and platelets in the body.
Shortage of blood-forming cells in the blood leads to symptoms such as abnormal bleeding and bruising, blood clots, excessive tiredness, pale skin, pain in affected areas, loss of appetite and weight loss. Tretinoin reduces the growth of diseased blood cells by inducing initial maturation and proliferation of the immature promyelocytes accumulated in the bone marrow.
This medicine can be taken preferably with a meal or shortly thereafter. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and health condition. The most common side effects of taking this medicine are headache, nausea, vomiting, skin rash, stomach pain and fever. Contact your doctor if any of the symptom bothers you.
ATRANZA 10MG should be used with caution in patients who have ever had any mental problems like depression or mood changes in the past, as tretinoin could aggravate them. Before taking this medicine, inform your doctor if you are pregnant or you think you are pregnant, because tretinoin can cause harm to your unborn baby. Your doctor will suggest a suitable method for contraception. Also, you should not get pregnant during or within 1 month after stopping treatment with tretinoin. Tretinoin can pass through breast milk, and therefore should not be used in lactating mothers.