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INTRODUCTION
ATELOL D TABLET is a combination of Atenolol and Indapamide which belongs to the group of medicines called Beta blockers and Thiazide diuretics. It is used to treat high blood pressure in adult patients and reduces the risk of heart disease, kidney disease, and stroke. It is a common condition in which the force of the blood is consistently high against the walls of the arteries, which can increase the risk of heart disease, kidney disease, and stroke.
Before taking ATELOL D TABLET, inform your doctor if you have diabetes, kidney or liver problems, heart problems, thyroid problems, asthma, or gout. Take ATELOL D TABLET with or without food, and include potassium-rich foods in your diet (bananas, dried fruits) to balance the loss of potassium levels due to this medicine.
Before taking ATELOL D TABLET, inform your doctor if you are pregnant or breastfeeding. If you are elderly and over 65 years of age, consult your doctor before taking this medicine. The most common side effects of this medicine are nausea, tiredness, drowsiness, and a low pulse rate.
USES OF ATELOL D TABLET
- Treats high blood pressure
HOW ATELOL D TABLET WORKS
ATELOL D TABLET helps to reduce high blood pressure, where atenolol works by reducing the force of contraction of the heart muscles by blocking the effects of certain hormones called adrenaline and making the heart beat more easily, thus lowering the blood pressure, and indapamide exerts its diuretic effect by decreasing the extra fluid volume and also works by preventing reabsorption of sodium in the kidneys, which in turn relaxes the blood vessels and makes the blood flow more easily in the passage of the blood vessels and thus lowers the blood pressure.
DIRECTIONS FOR USE
Always take this medicine as directed by your doctor. Take this medicine with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Do not stop taking this medicine on your own, without informing your doctor.
SIDE EFFECTS OF ATELOL D TABLET
COMMON
- nausea
- diarrhea
- tiredness
- low pulse rate
- cold hands and feet
- drowsiness
- red raised skin rash
UNCOMMON
- sleep disturbances
- muscle weakness
- vomiting
- purple spots on the skin (purpura)
RARE
- mood changes
- dry mouth
- dry eyes
- headache
- confusion
- hair thinning
- jaundice
- tingling sensation in hands
- spasm and numbness in fingers followed by warmth and pain
- visual disturbances
- impotence (inability to achieve erection)
- constipation
- myopia (unable to see long objects clearly)
- dizziness
Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:
- severe skin reactions such as stevens-johnson syndrome (skin rash, itching, blistering reddening of skin all over the body, peeling and swelling of the skin, swelling of the mucous membrane)
- angioedema or urticaria (such as rash, swelling of the face, lips, mouth, throat, or airways which can lead to difficulty in breathing or swallowing)
- signs of an inflamed pancreas (severe pain in stomach and back, and not being well)
- signs of an inflamed liver (nausea, severe stomach pain, tiredness and yellowing of skin or white of the eyes)
- serious irregular heartbeat
- liver problems leading to brain disease (hepatic encephalopathy)
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
Drink plenty of fluids such as water, electrolytes (ORS) or fruit juices to avoid dehydration in your body.
Nausea:
Try to take this medicine with, or just after, a meal or snack and stick to simple meals and do not eat oil-rich or spicy food.
Tiredness:
Try taking a balanced diet and drinking a good amount of fluids. Do minimal regular physical exercises which may help to reduce tiredness and get enough quality sleep.
WARNING & PRECAUTIONS
PREGNANCY
ATELOL D TABLET is not recommended for use in pregnant women. Consult your doctor for advice before taking ATELOL D TABLET.
BREASTFEEDING
ATELOL D TABLET is not recommended for use in breastfeeding women. Consult your doctor for advice before taking the medicine.
DRIVING AND USING MACHINES
ATELOL D TABLET may cause side effects such as dizziness or tiredness due to low blood pressure, so use caution while driving or operating heavy machinery.
ALCOHOL
Consumption of alcohol is not recommended during treatment with ATELOL D TABLET.
KIDNEY
ATELOL D TABLET should be used with caution in patients with kidney problems and it is not recommended for use in patients with severe kidney disease. Consult with your doctor for advice before taking ATELOL D TABLET.
LIVER
ATELOL D TABLET should be used with caution in liver disease patients and it is not recommended for use in patients with severe liver disease. Consult with your doctor for advice before taking this medicine.
ALLERGY
Do not take this medicine if you are allergic to ATELOL D TABLET or other inactive preparations of this medicine.
HEART DISEASE
ATELOL D TABLET should not be used in patients with heart problems such as heart failure, chest pain, second or three-degree heart block, or irregular or slow heartbeat. Consult with your doctor for advice before taking ATELOL D TABLET.
OTHERS
This medicine is not recommended for you if you have:
- hepatic encephalopathy
- phaeochromocytoma
- metabolic acidosis (abnormal levels of acid in your blood)
Before taking this medicine, inform your doctor if you have:
- thyroid or parathyroid disease (leads to low or high levels of calcium), thyrotoxicosis (overactive thyroid)
- diabetes
- porphyria (blood disorder)
- low levels of potassium (hypokalaemia) or sodium (hyponatremia) in the blood
- gout (swelling and painful joints)
- asthma, wheezing or other breathing problems
- allergic problems with natural sunlight or UV rays (photosensitivity reactions)
Use in pediatrics:
ATELOL D TABLET is not recommended for use in children. Consult with your doctor for advice before taking the medicine.
Use in geriatrics:
ATELOL D TABLET should be used with caution in elderly patients especially those suffering from kidney problems. Consult with your doctor for advice before taking ATELOL D TABLET.
INTERACTIONS
A. Drug-Drug interactions:
Inform your doctor, if you are taking,
- quinidine, amiodarone, and disopyramide (used to treat irregular heartbeat)
- digoxin (used to treat heart problems)
- ibuprofen, indomethacin (used to treat pain and swelling)
- adrenaline (used to stimulate the heart)
- insulin or metformin, glimepiride (used to treat diabetes)
- verapamil, diltiazem, nifedipine (used for high blood pressure or chest pain)
- clonidine (used to treat migraine or high blood pressure)
- lithium (used to treat depression)
- baclofen (used as muscle relaxant)
- amphotericin B (used to treat fungal infections)
- ciclosporin or tacrolimus (used to prevent organ rejection transplant)
- moxifloxacin, erythromycin (used to treat bacterial infections)
- haloperidol, amisulpride, sulpiride (used to treat depression or psychosis)
- pentamidine (used to treat pneumonia)
- allopurinol (used to treat gout)
- calcium supplements or calcium medicines
Overdosage:
If you or anyone else accidentally take too much of ATELOL D TABLET, consult your doctor immediately. Overdosage may cause side effects such as nausea, vomiting, low blood pressure, slow heart rate, drowsiness, bronchospasm (constriction of air passages in the lungs) and electrolyte disturbances.
SYNOPSIS
| Drug | : | Atenolol, Indapamide |
| Pharmacological Category | : | Beta-blockers, Thiazide diuretics |
| Therapeutic Indication | : | Hypertension |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep out of reach from children
- Store at room temperature below 25°C
FAQs ABOUT ATELOL D TABLET
Can ATELOL D TABLET cause kidney problems?
Yes, ATELOL D TABLET can cause kidney problems, but it should be used with caution in patients with mild to moderate kidney disease. ATELOL D TABLET should not be used in patients who have severe kidney problems. Your doctor will assess your kidney function regularly through blood tests.
What should I do if I miss taking ATELOL D TABLET?
You should take ATELOL D TABLET immediately when you remember. If it is time for your next dose, skip the dose and follow your regular dose schedule. Do not double the dose to make up for your missed dose.
Can I take ATELOL D TABLET before driving?
Do not take ATELOL D TABLET before driving as it can cause side effects such as dizziness and vision problems due to low blood pressure. You may ask someone to drive for you or find alternative measures by consulting your doctor.
Can I take ATELOL D TABLET during pregnancy?
No, pregnant women or those planning to become pregnant should not take ATELOL D TABLET, because it may harm the developing foetus. Your doctor may prescribe the safest antihypertensive drug during pregnancy.
REFERENCES
1. KD Tripathi. Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 563 & 561.
2. O De Divitiis, S Di Somma, M Petitto, S Fazio, V Ligouri. Indapamide and atenolol in the treatment of hypertension: double-blind comparative and combination study. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 1983. [Accessed 3rd March 2022] https://pubmed.ncbi.nlm.nih.gov/6354604/
3. Accord Healthcare Limited, Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed 3rd March 2022] https://www.medicines.org.uk/emc/files/pil.6025.pdf
4. S.C. Zentiva S.A., Electronic Medicines Compendium (EMC). [Revised in September 2021] [Accessed 3rd March 2022] https://www.medicines.org.uk/emc/files/pil.4188.pdf
5. AstraZeneca Pharmaceuticals LP. U.S. Food & Drug Administration. [Revised in July 2011] [Accessed 3rd March 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018240s031lbl.pdf
6. STADA Arzneimittel AG, Health Products Regulatory Authority (HPRA). [Revised in June 2017] [Accessed 3rd March 2022] https://www.hpra.ie/img/uploaded/swedocuments/PIL-2194090-22062017180446-636337515623281250.pdf
USEFUL DIAGNOSTIC TESTS
- Kidney Function Test
PRODUCT DETAILS
ALTERNATE BRANDS
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