Aplevant 0.75Mg Injection 0.5ml

Diabetes Rx required
OUT OF STOCK

Best Price*  ₹ 3,998.40
MRP ₹4,998.00
(Inclusive of all taxes) *This product cannot be returned for a refund or exchange. * Mfr: Lupin Ltd * Country of Origin: India



INTRODUCTION

APLEVANT 0.75MG contains dulaglutide is Glucagon-like Peptide-1 Agonists (GLP-1 Agonist) which belongs to the class of medications called incretin mimetics. It is used to lower blood sugar (glucose) in adults with type 2 diabetes mellitus and can help to prevent the heart disease. Type 2 diabetes is a condition in which body does not make enough insulin, and the insulin that your body produces does not work as well as it should. When this happens, sugar (glucose) builds up in blood.

GLP-1 makes your pancreas to produce more insulin after you eat and helps in maintaining blood glucose levels in the normal range. It helps the pancreas to release the right amount of insulin when blood sugar levels are high. Insulin helps in moving sugar from the blood into other body tissues where it is used for energy.

Always use this medicine as doctor told you. It is not recommended for the children and adolescents under 18 years of age. It is not recommended for use in people with the severe stomach or intestinal problems. Do not take APLEVANT 0.75MG if you are pregnant or breast feeding, or if you are trying to become pregnant. Consult your doctor for advice. The most common side effects such as nausea, diarrhea, vomiting, decreased appetite, indigestion.

USES OF APLEVANT 0.75MG

  • Treat type 2 diabetes mellitus

HOW APLEVANT 0.75MG WORKS

APLEVANT 0.75MG activates GLP-1 receptor, a membrane-bound cell-surface receptor coupled to adenylyl cyclase in the pancreatic beta cells. GLP-1 makes your pancreas to produce more insulin after you eat and helps in maintaining blood glucose levels in the normal range. It helps the pancreas to release the right amount of insulin when blood sugar levels are high. Insulin helps in moving sugar from the blood into other body tissues where it is used for energy.

DIRECTIONS FOR USE

Always use APLEVANT 0.75MG as doctor told you. It is injected under the skin (subcutaneous injection) of your stomach area (abdomen) or upper leg (thigh). If the injection is given by someone else, they may inject in upper arm. It may be taken with or without food.

SIDE EFFECTS OF APLEVANT 0.75MG

SERIOUS

  • anaphylactic reactions, angioedema (symptoms are rashes, itching and rapid swelling of the tissues of the neck, face, mouth or throat, hives and difficulties breathing)

COMMON

  • low blood sugar
  • nausea and vomiting
  • diarrhea, abdominal (stomach) pain
  • feeling less hungry (decreased appetite)
  • indigestion
  • constipation
  • bloating of the stomach

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Diarrhea:

Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicines consulting your doctor.

WARNING & PRECAUTIONS

PREGNANCY

APLEVANT 0.75MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

APLEVANT 0.75MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

If you use APLEVANT 0.75MG in combination with a sulphonylurea or insulin, low blood sugar (hypoglycaemia) may occur which may reduce your ability to concentrate. Please keep this in mind in all situations where you might put yourself and others at the risk.

ALCOHOL

Consumption of alcohol is not recommended during treatment with this medicine.

KIDNEY

APLEVANT 0.75MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

LIVER

APLEVANT 0.75MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take if you are allergic to the medicine.

OTHERS

Do not use APLEVANT 0.75MG if you:

  • or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC)
  • severe stomach or intestinal problems

INTERACTIONS

Talk to your doctor if you are using, have recently used or might use any other medicine.

SYNOPSIS

Drug :   Dulaglutide
Pharmacological Category :   Glucagon-like Peptide-1 Agonists (GLP-1 Agonist)
Therapeutic Indication :   Type II Diabetes mellitus
Dosage Forms :   Injection

MORE INFORMATION

Store at temperature 2-8°C and keep out of reach of children. Do not freeze.

FAQs ABOUT APLEVANT 0.75MG

Can APLEVANT 0.75MG be used in pregnant women?

No. It is not recommended for use in the pregnant women. Consult your doctor before taking.

How long can you stay on APLEVANT 0.75MG?

It may take this medicine up to 5 weeks to start lowering your blood glucose levels but the maximum effect will not be seen for 3-6 months.

What is APLEVANT 0.75MG made of?

It is novel glucagon-like peptide-1 agonist (GLP-1) and biologic drug consisting of the dipeptidyl peptidase-IV-protected GLP-1 analogue covalently linked to human IgG4-Fc heavy chain by a small peptide linker.

REFERENCES

1. Celeste B Burness, Lesley J Scott; Dulaglutide: A Review in Type 2 Diabetes; [Published on Dec 2015] https://pubmed.ncbi.nlm.nih.gov/26423061/

2. Eli Lilly and Company; Trulicity (dulaglutide) for the Treatment of Type 2 Diabetes [Published on 2014] https://www.clinicaltrialsarena.com/projects/trulicity-type-2-diabetes/

3. Eli Lilly and Company Indianapolis, IN 46285, USA; U.S. Food & Drug Administration; [Revised on Jan 2017] [Accessed 04 Nov 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/125469s007s008lbl.pdf

4. Eli Lilly Italia S.p.A.,Via Gramsci 731/733, 50019, Sesto Fiorentino, Firenze (FI), Italy; Electronic Medicines Compendium (EMC); [Revised on Oct 2019] [Accessed 04 Nov 2020] https://www.medicines.org.uk/emc/files/pil.3634.pdf

Marketer DETAILS

    Country Of Origin
    India
ALTERNATE SALTS
Trulicity 0.75mg Injection(Pfs) 2X0.5ml
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Rs.4,998.00
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