AMTAS LP Tablet 10's

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Amlodipine Besylate+Lisinopril
By Intas Pharmaceuticals Ltd
Prescription Needed
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Drug Information for AMTAS LP Tablet 10's

What is AMTAS LP Tablet used for?

AMTAS LP Tablet is used in the treatment of:

  • Mild to moderate hypertension (high blood pressure);
  • Hypertension not responding to monotherapy (single drug therapy) with either calcium channel blocker or angiotensin converting enzyme inhibitor (ACE-inhibitor).

AMTAS LP Tablet may also be prescribed for other conditions as determined by your doctor.

How does AMTAS LP Tablet work?

  • Amlodipine Besylate belongs to a group of medicines known as calcium channel blockers. Amlodipine Besylate prevents the calcium from moving into the blood vessel wall thereby preventing tightening of blood vessel walls. This reduces the blood pressure and improves symptoms of chest pain.
  • Lisinopril belongs to a group of medicines known as angiotensin converting enzyme inhibitors (ACE-inhibitors). Lisinopril acts by suppressing the renin-angiotensin system (physiological system in our body which regulates blood pressure). Lisinopril widens and relaxes the blood vessel walls and reduces the blood pressure.

AMTAS LP Tablet act additively and relaxes the blood vessel wall which improves the blood flow, thereby reducing the blood pressure.

How to take AMTAS LP Tablet?

  • The dosage of oral tablets of AMTAS LP Tablet depends on the age, weight and medical condition of an individual. Take AMTAS LP Tablet as prescribed by your doctor.
  • You must swallow the tablet with water. Do not chew the tablet.
  • AMTAS LP Tablet can be taken before, during or after a meal.
  • Take your daily dose at same time.
  • Do not discontinue the medication without consulting a doctor.
  • If you miss a dose of AMTAS LP Tablet, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.
  • Amlodipine + Lisinopril is not recommended for use in children under 18 years of age.
  • If you have taken an overdose of AMTAS LP Tablet, please contact your doctor immediately. The only symptom of overdose of Amlodipine + Lisinopril is hypotension (low blood pressure).

What are the drugs that interact with AMTAS LP Tablet?

Drugs that interact with AMTAS LP Tablet:

  • Allopurinol
  • Anticancer drugs
  • Antihypertensive
  • Carbamazepine, Phenobarbital, Phenytoin
  • Dantrolene
  • Diuretics
  • Drugs which increase serum potassium levels
  • Ephedrine
  • Heparin
  • Indomethacin
  • Insulin and oral anti-diabetics
  • Ketoconazole, Itraconazole
  • Lithium
  • Morphine
  • NSAIDs (non-steroidal anti-inflammatory drugs)
  • Procainamide
  • Rifampicin, Erythromycin, Clarithromycin
  • Ritonavir, Indinavir, Nelfinavir
  • Salbutamol, Xylometazoline
  • Simvastatin
  • John’s wort
  • Verapamil, Diltiazem

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of AMTAS LP Tablet?

Most common side effects of AMTAS LP Tablet. are:

  • Nausea
  • Dizziness
  • Headache, fatigue
  • Breathlessness, palpitation
  • Swelling of ankles, feet, legs, hands or arms
  • Flushing
  • Diarrhoea or constipation

Please stop your tablets and contact your physician immediately if you have

  • angioneurotic oedema (red, burning, itching areas on skin near eyes, lips, hands, feet and inside of throat, hoarseness of voice, difficulty in breathing);
  • increase in serum creatinine levels, increase BUN (blood urea nitrogen) or increase in serum potassium.

This is not a comprehensive list of side effects. Consult your doctor to know more about other possible side effects.

What special precautions AMTAS LP Tablet?

  • Seek doctor’s advice before taking any other drug or herbal products while on AMTAS LP Tablet.
  • Get up slowly after sitting or lying down as AMTAS LP Tablet may cause dizziness and light-headedness.

You are advised not to take AMTAS LP Tablet if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discoloration.

What should you tell your doctor before taking AMTAS LP Tablet?

Tell your doctor if

  • you are allergic to AMTAS LP Tablet or to any ingredients of this medicine.
  • you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • you are on low salt diet and are using potassium supplements.
  • you have high levels of potassium in your blood.
  • you have a previous history of angioedema.
  • you have narrowing of aorta (aortic stenosis) or heart valve (mitral stenosis).
  • you have had myocardial infarction with heart failure.
  • you have any pre-existing heart disease.
  • you have liver or kidney disease.
  • you have diabetes.
  • you are under dialysis.
  • you are planning a surgery or any procedure.
  • you are pregnant or trying to conceive or are breastfeeding.

Frequently Asked Questions about AMTAS LP Tablet

  1. How should AMTAS LP Tablet be stored?
  2. AMTAS LP Tablet should be stored between 15° to 30°C. Keep the medicine away from sunlight and do not freeze the medicine. Keep the medicine out of reach from children.

  3. Can I drive while taking AMTAS LP Tablet?

  4. AMTAS LP Tablet may cause drowsiness, dizziness and headache in some individuals. Avoid driving if you are taking AMTAS LP Tablet.

  5. Should I follow any special dietary instructions while taking AMTAS LP Tablet?
  6. Do not take grapefruit or grapefruit juice while on AMTAS LP Tablet. Apart from this, there are no dietary restrictions if you are taking AMTAS LP Tablet.

  7. Is AMTAS LP Tablet addictive?
  8. No, AMTAS LP Tablet is not addictive. However, do not take it without consulting your doctor.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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