INTRODUCTION
AMLOVAS 10 TABLET contains Amlodipine which belongs to the group of medicines called Antihypertensive agents. It is used to treat hypertension and certain type of angina (chest pain) called as Prinzmetal or variant angina.
Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the arteries remains very high, and as a result it may lead to severe damage to the blood vessels supplying vital organs, such as heart, kidney or brain. If left untreated, it may cause serious complications such as heart attack, heart failure, stroke or even blindness.
Angina is a type of chest pain caused due to decreased blood flow and oxygen supply to the heart muscles. It is characterized by a sharp chest pain originating from the heart and radiating until left shoulder along with severe chest tightness or heaviness, and difficulty in breathing.
Take AMLOVAS 10 TABLET as advised by your physician. Avoid drinking grapefruit juice while taking AMLOVAS 10 TABLET, as it could lead to unpredictable increase in the blood pressure lowering effects of AMLOVAS 10 TABLET.
Before taking AMLOVAS 10 TABLET, inform your doctor if you have any liver problems. You must also inform your doctor if you have severe uncontrollable increase in blood pressure or recently had heart attack.
AMLOVAS 10 TABLET is not recommended for use in patients with other severe heart problems such as narrowing of heart valves or cardiogenic shock. It is also not suitable for use in patients with severe hypotension (low blood pressure).
Consult your doctor before taking AMLOVAS 10 TABLET if you are pregnant or breastfeeding. The most common side effects of taking AMLOVAS 10 TABLET are swelling of ankles or other body parts, headache, dizziness, sleepiness, tiredness, racing heartbeat, indigestion, constipation and muscle cramps. Contact your doctor if any of these side effects trouble you.
USES OF AMLOVAS 10 TABLET
It is used to treat:
- Hypertension
- Angina (such as Prinzmetal Angina)
HOW AMLOVAS 10 TABLET WORKS
AMLOVAS 10 TABLET is a vasodilator. It works by blocking the entry of certain ions (calcium ions) within the blood vessels that causes narrowing. As a result, it relaxes the blood vessels and allows blood to flow more smoothly across the blood vessels with less pressure.
In patients with angina, AMLOVAS 10 TABLET acts by improving the blood flow and oxygen supply to the heart muscles. This reduces the strain on the heart and improves heart functions.
DIRECTIONS FOR USE
Take AMLOVAS 10 TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Continue to take AMLOVAS 10 TABLET for the stipulated duration instructed by your doctor to achieve better results.
SIDE EFFECTS OF AMLOVAS 10 TABLET
COMMON
- edema (swelling of the ankles or other body parts)
- headache, dizziness, sleepiness
- palpitations (fast heartbeat)
- flushing (redness and warmth of the skin)
- stomach pain, nausea, diarrhea, constipation, indigestion
- changes in bowel habit
- tiredness, weakness
- visual disturbances, double vision
- muscle pains
UNCOMMON
- anxiety, depression
- insomnia (sleeplessness)
- changes in taste
- tingling sensation in limbs, loss of pain sensation
- ringing in the ears
- low blood pressure
- increased sweating
- increased urination at night
- inability to obtain an erection, enlargement of the breasts in men
- joint pain, back pain
- weight gain or decrease in weight
RARE
- confusion
Stop taking AMLOVAS 10 TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
- severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane)
- chest pain, shortness of breath (signs of heart attack)
- inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Take AMLOVAS 10 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Constipation:
Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
WARNING & PRECAUTIONS
PREGNANCY
AMLOVAS 10 TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
BREASTFEEDING
AMLOVAS 10 TABLET should be used with caution in breastfeeding women as it may pass through the breast milk to the nursing infant. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
AMLOVAS 10 TABLET should be used with caution in breastfeeding women as it may pass through the breast milk to the nursing infant. Therefore, consult your doctor before taking it.
ALCOHOL
Avoid consumption of alcohol while taking AMLOVAS 10 TABLET as it could make you feel dizzier.
LIVER
AMLOVAS 10 TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take AMLOVAS 10 TABLET if you are allergic to Amlodipine or to any other calcium antagonists (such as nifedipine, diltiazem).
HEART DISEASE
AMLOVAS 10 TABLET is not recommended for use in patients with severe heart problems such as heart failure, aortic stenosis (narrowing of arteries) or cardiogenic shock (inability of heart to pump blood). It should be used with caution in patients having a history of recent heart attack or heart failure. Therefore, consult your doctor before taking it.
OTHERS
AMLOVAS 10 TABLET is not recommended for use if you have:
- severe low blood pressure (hypotension)
Before taking AMLOVAS 10 TABLET, inform your doctor if you have:
- severe uncontrollable increase in blood pressure (hypertensive crisis)
Use in pediatrics:
AMLOVAS 10 TABLET is not recommended for use in children aged below 6 years. It should be used in children and adolescents (aged between 6-17 years) only if prescribed by the physician. Therefore, consult your doctor for advice before administration.
Use in geriatrics:
AMLOVAS 10 TABLET should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor for advice before taking it.
INTERACTIONS
A. Drug - Drug interactions:
Before taking AMLOVAS 10 TABLET, inform your doctor if you are taking any of the following medicines such as:
- other medicines used to treat high blood pressure or angina (Ex. diltiazem, verapamil)
- ketoconazole, itraconazole (used to treat fungal infections)
- ritonavir, indinavir, nelfinavir (used in treatment of HIV infections)
- rifampicin, erythromycin, clarithromycin (used to treat bacterial infections)
- dantrolene (a medicine used to treat muscle spasms)
- medicines used to control elevated cholesterol levels (Ex. simvastatin)
- medicines used to prevent graft rejection and to suppress immune functions (such as tacrolimus, sirolimus, temsirolimus, everlimus, cyclosporine)
- St. John’s wort (an herbal medicine used to treat depression)
B. Drug - Food interaction:
Avoid drinking grapefruit juice while taking AMLOVAS 10 TABLET, as it could lead to unpredictable increase in the blood pressure lowering effects of AMLOVAS 10 TABLET.
Overdosage:
If you or anyone else accidentally took more AMLOVAS 10 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include dizziness, fainting, light-headedness, weakness, shock, cool or clampy skin and shortness of breath.
SYNOPSIS
| Drug | : | Amlodipine |
| Pharmacological Category | : | Calcium Channel Blockers |
| Therapeutic Indication | : | Hypertension, Angina |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep AMLOVAS 10 TABLET out of the sight and reach of children
- Store AMLOVAS 10 TABLET at room temperature
FAQs ABOUT AMLOVAS 10 TABLET
What are the uses of AMLOVAS 10 TABLET?
AMLOVAS 10 TABLET is used to treat hypertension and certain forms of angina (Prinzmetal angina).
What type of a medicine is AMLOVAS 10 TABLET?
AMLOVAS 10 TABLET is an antihypertensive medicine. It contains amlodipine which is a calcium channel blocker. It reduces strain on the heart, relaxes blood vessels and makes the heart to pump more blood with lesser force.
What happens when I stop taking AMLOVAS 10 TABLET?
Do not stop taking AMLOVAS 10 TABLET without consulting your doctor as your blood pressure may raise once again. Make sure to take AMLOVAS 10 TABLET for the stipulated duration recommended by your doctor to achieve maximum results.
What is the best time to take AMLOVAS 10 TABLET?
AMLOVAS 10 TABLET can be taken with or without meals. Your doctor will decide the best time for you to take AMLOVAS 10 TABLET based on your age, body weight and disease condition.
What to do if I forgot to take a dose of AMLOVAS 10 TABLET?
If you have missed a dose of AMLOVAS 10 TABLET, take it as soon as you remember. However, if it is time for the next dose of AMLOVAS 10 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of AMLOVAS 10 TABLET to compensate the missed ones.
What precautions should be followed while taking AMLOVAS 10 TABLET?
Before taking AMLOVAS 10 TABLET, inform your doctor if you have any liver problems. You must also inform your doctor if you have severe high or low blood pressure, or other heart problems (such as narrowing of the arteries, cardiogenic shock or a recent heart attack). Consult your doctor before taking AMLOVAS 10 TABLET if you are pregnant and breastfeeding. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.
Can I consume alcohol while taking AMLOVAS 10 TABLET?
Avoid consumption of alcohol while taking AMLOVAS 10 TABLET as it might make you feel dizzier and drowsier.
What happens if I accidentally take more AMLOVAS 10 TABLET?
If you or anyone else accidentally took more AMLOVAS 10 TABLET, consult your doctor immediately. Symptoms of overdosage might include dizziness, fainting, light-headedness, weakness, shock, cool or clampy skin and shortness of breath.
Can I take AMLOVAS 10 TABLET daily?
Take AMLOVAS 10 TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take AMLOVAS 10 TABLET every day or not.
Can AMLOVAS 10 TABLET cause ankle swelling?
AMLOVAS 10 TABLET may cause edema or swelling of ankles in few patients. If you experience ankle swelling, keep your legs on a table or slightly elevated from the ground level. If this symptom bothers you, contact your doctor.
What are the side effects of AMLOVAS 10 TABLET?
The most common side effects of taking AMLOVAS 10 TABLET are low blood pressure, dizziness, tiredness, headache, sleepiness, swollen ankles, and flushing. Contact your doctor if any of these side effect worsens.
Can I stop taking AMLOVAS 10 TABLET once my symptoms subside?
No. Do not stop taking AMLOVAS 10 TABLET without consulting your doctor. As hypertension is a chronic condition, long term treatment may be necessary to control its symptoms. Therefore, take AMLOVAS 10 TABLET as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.
Can AMLOVAS 10 TABLET be taken during pregnancy?
AMLOVAS 10 TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
Can the use of AMLOVAS 10 TABLET affect the liver?
Yes. AMLOVAS 10 TABLET may affect the way your liver work. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.
Can AMLOVAS 10 TABLET cause erectile dysfunction?
AMLOVAS 10 TABLET may cause problems in erection in few individuals. Consult your doctor if it bothers you.
REFERENCES
1. KD Tripathi. Antianginal and Other Anti-ischaemic Drugs. Antihypertensive Drugs. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 549 & 562.
2. Hassan Fares, James J DiNicolantonio, James H O'Keefe, and Carl J Lavie. Amlodipine in hypertension: a first-line agent with efficacy for improving blood pressure and patient outcomes. NIH. National Library of Medicine, National Center for biotechnology information. PMC. PubMed Central. September 2016. [Accessed on 1st October 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051471/
3. Kishen G. Bulsara; Manouchkathe Cassagnol. Amlodipine. StatPearls. NIH. National Library of Medicine, National Center for biotechnology information. PMC. PubMed Central. January 2022. [Accessed on 1st October 2022]. https://www.ncbi.nlm.nih.gov/books/NBK519508/
4. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 1st October 2022]. https://www.medicines.org.uk/emc/files/pil.3478.pdf
5. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 1st October 2022]. https://www.medicines.org.uk/emc/files/pil.13960.pdf
USEFUL DIAGNOSTIC TESTS
- Kidney function tests
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