AMICLINE PLUS TABLET is a combination of Ornidazole and Diloxanide which belongs to the group of medicines called Antibiotics and Anti-protozoal agents respectively. It is used in the treatment of intestinal and extraintestinal amoebiasis (parasitic infection of the intestines caused by the amoeba Entamoeba histolytica). It is also used to treat diarrhea (amoebic etiology) and giardiasis (diarrheal infection of small intestine caused by Giardia lamblia).
Your doctor might want you to make certain lifestyle changes such as maintaining good hygiene, eating a healthy diet and drinking plenty of fluids.
Do not consume alcohol while taking AMICLINE PLUS TABLET. Consult your doctor for advice before taking this medicine.
Before taking AMICLINE PLUS TABLET inform your doctor if you have liver, kidney or heart disease, epilepsy or multiple sclerosis (affecting brain).
AMICLINE PLUS TABLET is not recommended for use in pregnant and breastfeeding women. It is not recommended for use in children and adolescents below 12 years of age.
AMICLINE PLUS TABLET should be used with caution in elderly patients. The most common side effects of taking AMICLINE PLUS TABLET are nausea, vomiting, dizziness, abdominal cramp, loss of appetite. Consult your doctor if symptoms worsen or persists for a longer duration.
It is used to treat:
AMICLINE PLUS TABLET is a combination of Ornidazole and Diloxanide. Ornidazole belongs to antibiotics which works against bacteria and other microorganisms that cause infections by damaging the DNA. Diloxanide belongs to amoebicide which works inside the large intestine to destroy the infection causing amoeba (parasites).
Take AMICLINE PLUS TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition.
Stop taking AMICLINE PLUS TABLET and contact your doctor immediately if you experience any of the following side effects:
Nausea or Vomiting:
Stick to simple meals. Avoid eating oily or spicy food. Consult your doctor if symptoms does not improve.
Flatulence:
Eat smaller and frequent meals. If the symptom does not improve, consult your doctor.
Stomach pain:
Try to rest and relax. Eat and drink slowly. Keep a heat. Consult your doctor if symptoms don’t improve.
Headache:
Avoid bright lights, take enough rest and drink lots of water. Consult your doctor if symptoms don’t improve.
AMICLINE PLUS TABLET is not recommended for use in women who are pregnant or planning to have a baby. Consult your doctor before taking it.
AMICLINE PLUS TABLET is not recommended for use in breastfeeding women as it is unknown if it passes through breastmilk. Consult your doctor before taking it.
Do not drive or use any heavy machines while taking AMICLINE PLUS TABLET as it can make you dizzy.
Do not consume alcohol while taking AMICLINE PLUS TABLET due to increased risk of side effects.
AMICLINE PLUS TABLET should be used with caution in patients with kidney disease. Dose will be adjusted by your doctor. Consult your doctor before taking.
AMICLINE PLUS TABLET should be used with caution in patients with liver disease. Dose will be adjusted by your doctor. Consult your doctor before taking.
Do not take AMICLINE PLUS TABLET if you are allergic to Ornidazole or Diloxanide or any other ingredients of this medicine.
Before taking AMICLINE PLUS TABLET, inform your doctor if you:
Use in Pediatrics:
AMICLINE PLUS TABLET is not recommended for use in children and adolescents below 12 years of age. Consult your doctor before taking.
Use in Geriatrics:
AMICLINE PLUS TABLET should be used with caution in elderly patients above 65 years of age. Consult your doctor before taking.
A. Drug - Drug interactions:
Before taking AMICLINE PLUS TABLET, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally takes too much of AMICLINE PLUS TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are dizziness, nausea, headache.
Drug | : | Ornidazole, Diloxanide |
Pharmacological Category | : | Nitroimidazole, Amebicide |
Therapeutic Indication | : | Intestinal and extraintestinal amoebiasis, Diarrhea, Giardiasis |
Dosage Forms | : | Tablet |
Q: What is AMICLINE PLUS TABLET used for?
A: AMICLINE PLUS TABLET is used in the treatment of intestinal and extraintestinal amoebiasis (parasitic infection of the intestines caused by the amoeba Entamoeba histolytica). It is also used to treat diarrhea (amoebic etiology) and giardiasis (diarrheal infection of small intestine caused by Giardia lamblia).
Q: Can I consume alcohol while taking AMICLINE PLUS TABLET?
A: No, do not consume alcohol while taking AMICLINE PLUS TABLET as it will increase the side effects of the medicine. Consult your doctor for more information on this.
Q: Can I drive while taking AMICLINE PLUS TABLET?
A: No, avoid driving or using machines while taking AMICLINE PLUS TABLET as it can make you feel dizzy and it is not safe. See how the medicine affects you and consult your doctor for more information.
Q: What are the common side effects of AMICLINE PLUS TABLET?
A: The most common side effects of taking AMICLINE PLUS TABLET are nausea, loss of appetite, flatulence, dizziness, headache, abdominal pain and cramps, change in taste.
Q: Can AMICLINE PLUS TABLET be used in pregnant women?
A: No, AMICLINE PLUS TABLET is not recommended for use in women who are pregnant or planning to be pregnant as it is unsafe for the baby.
1. KD Tripathi. Antiamoebic and Other Antiprotozoal Drugs. Essentials of medical pharmacology. Eighth Edition. 2019. Page –897.
2. Yehouda Marcus, Noam Tal, Mordechai Ronen, Raanan Carmieli, Michael Gurevitz. The drug ornidazole inhibits photosynthesis in a different mechanism described for protozoa and anaerobic bacteria. [Accessed on 18th June 2022] https://pubmed.ncbi.nlm.nih.gov/27647935/
3. D E Schwartz, F Jeunet. Comparative pharmacokinetic studies of ornidazole and metronidazole in man. [Accessed on 18th June 2022] https://pubmed.ncbi.nlm.nih.gov/1253627/
4. Franco-Indian Pharmaceuticals Pvt. Ltd. Diloxanide furoate + Ornidazole. [Accessed on 18th June 2022] http://www.francoindian.com/products/amicline-plus.htm
5. Diloxanide furoate. Pubchem. [Accessed on 18th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Diloxanide-furoate
6. Teva Pharma (New Zealand) Limited. Ornidazole. [Revised in May 2017] [Accessed on 18th June 2022] https://medsafe.govt.nz/Consumers/CMI/a/arrowornidazole.pdf
7. Ornidazole. Health Products Regulatory Authority (HPRA). [Revised in June 2021] [Accessed on 18th June 2022] https://go.drugbank.com/drugs/DB13026
8. Ornidazole. Sciencedirect. [Accessed on 18th June 2022] https://www.sciencedirect.com/topics/neuroscience/ornidazole
9. Diloxanide furoate. Sciencedirect. [Accessed on 18th June 2022] https://www.sciencedirect.com/topics/neuroscience/diloxanide-furoate
10. Diloxanide furoate. Patient info. [Revised on March 2022] [Accessed on 18th June 2022] https://patient.info/medicine/diloxanide-tablets
11. Diloxanide furoate. Ornidazole. Healthline. [Revised in September 2018] [Accessed on 18th June 2022] https://www.healthline.com/health/giardiasis
12. Diloxanide furoate. Ornidazole. Healthline. [Revised in January 2022] [Accessed on 18th June 2022] https://www.healthline.com/health/amebiasis
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