Ambrican 5mg Tablet 10'S

Hypertension Rx required

Best Price*  ₹ 1,576.68
MRP ₹1,970.85
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mfr: Lupin Ltd * Country of Origin: India
TOTAL AMOUNT ₹ 1,970.85

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INTRODUCTION

AMBRICAN 5MG contains Ambrisentan which belongs to a group of medicines called other antihypertensives. It is used to treat pulmonary arterial hypertension (PAH). PAH is high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs. It widens the pulmonary arteries, making it easier for the heart to pump blood through them. This lowers the blood pressure and relieves the symptoms. It may also be used in combination with other medicines used to treat PAH.

Take AMBRICAN 5MG according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. Do not drive or operate machinery while taking this medicine, since it may cause low blood pressure, dizziness, tiredness. This medicine is not recommended for children and adolescents under 18 years of age. Do not take this medicine if you are pregnant or breastfeeding. The common side effects of this medicine are rash, itching and swelling, low blood pressure, stuffy nose, inflamed nasal passages, headache, fast heartbeat, nausea, diarrhea and constipation.

USES OF AMBRICAN 5MG

  • Treats Pulmonary arterial hypertension (PAH)

HOW AMBRICAN 5MG WORKS

AMBRICAN 5MG works by stopping the action of endothelin, a natural substance that causes blood vessels to narrow and prevents normal blood flow in people who have PAH.

DIRECTIONS FOR USE

Take this medicine according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. It may be taken with or without food.

SIDE EFFECTS OF AMBRICAN 5MG

SERIOUS

  • swelling all over the body
  • decreased sperm count
  • low red blood cell levels (anemia)

COMMON

  • rash, itching and swelling
  • swelling especially of the ankles and feet
  • light-headedness (low blood pressure)
  • flushing
  • stuffy nose
  • inflamed nasal passages
  • headache
  • fast heartbeat
  • nausea
  • diarrhoea
  • constipation

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Nausea:

Stick to simple meals and do not eat rich or spicy foods.

Constipation:

Add fruits, vegetables whole grains and other high-fiber foods to your diet. 

WARNING & PRECAUTIONS

PREGNANCY

AMBRICAN 5MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

AMBRICAN 5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate machinery while taking this medicine, since it may cause low blood pressure, dizziness, tiredness.

KIDNEY

AMBRICAN 5MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER

AMBRICAN 5MG is not recommended in patients with active liver diseases. Consult your doctor for advice.

ALLERGY

Do not take if you are allergic (hypersensitive) to Ambrisentan or any ingredients of this medicine.

HEART DISEASE

AMBRICAN 5MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.

OTHERS

Tell your doctor if you had or have a condition such as:

  • scarring of the lungs
  • anaemia
  • swelling in the hands, ankles or feet caused by fluid (peripheral oedema)
  • pulmonary veno-occlusive disease

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

  • cyclosporine A
  • rifampicin
  • iloprost, epoprostenol, sildenafil

SYNOPSIS

Drug :   Ambrisentan
Pharmacological Category :   Endothelin receptor Antagonist, Vasodilator    
Therapeutic Indication :   Pulmonary arterial hypertension
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT AMBRICAN 5MG

Can I stop taking AMBRICAN 5MG on my own?

No, you should not stop taking without consulting your doctor as this may worsen your condition.  

How should AMBRICAN 5MG be taken?

You can take it with or without food at any time of the day but prefer taking it at the same time each day. Swallow it whole with a glass of water.  

Can AMBRICAN 5MG cause liver problems?

It may rarely cause liver injury and inflammation of the liver because of the body’s own defences (autoimmune hepatitis). Consult your doctor if you have nausea, vomiting, loss of appetite, dark-colored urine and yellowing of the skin.

REFERENCES

1. Barnes PJ. Pulmonary Pharmacology. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 1059.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 39-50.

3. Soha M Elshaboury and Joe R Anderson. Ambrisentan for the treatment of pulmonary arterial hypertension: improving outcomes: Patient preference and adherence. 2013; [Accessed Oct 17, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652514/

4. Mylan Hungary Kft, [Accessed Oct 17, 2020] https://www.ema.europa.eu/en/documents/product-information/ambrisentan-mylan-epar-product-information_en.pdf

5. Gilead Sciences, Inc., 2007, U.S. Food & Drug Administration; [Revised Oct 2015] [Accessed Oct 17, 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022081s033lbl.pdf

VIDEOS

AMBRISENTAN TABLET - Drug Information

AMBRISENTAN TABLET : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

Manufacturer/Marketer Details

    Net Qty
    1
    Shelf Life
    NA
    Item Weight
    17.5
    No. of Units in a Kit
    NA
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Ambrican 5mg Tablet 10'S

Ambrican 5mg Tablet 10'S Mfr: Lupin Ltd

M.R.P.: Rs.1,970.85
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