Cold Storage Product cannot be returned or exchanged. Available at selected pin codes.
AMBISOME 50MG contains Amphotericin B which belongs to a group of medicines known as anti-fungal antibiotics. It is indicated for severe life threatening fungal infections and visceral leishmaniasis (developed by parasite).
Amphotericin B is an antifungal medicine, which can be fungistatic or fungicidal, depends on its concentration and fungal susceptibility, which acts by binding to ergosterol in the fungal cell membrane eventually causes membrane damage. This results in cell contents leak from the fungal cell and cell death happens. It has greater affinity for fungal ergosterol than for the cholesterol of human cells. Amphotericin B is a macrocyclic which is created from a strain of Streptomyces nodosus.
AMBISOME 50MG will be administered by physician or nurse, inform your physician if you have or had liver, kidney or heart problems, are pregnant women or breastfeeding mothers. This medicine is not suitable for babies less than 1 month old. The common side effects are nausea, vomiting, fever, chills and decrease in potassium levels.
Amphotericin B works by slowing the growth of fungi that causes infection.
AMBISOME 50MG will be administered as an infusion into a vein (drip) by physician or nurse.
Nausea:
Stick to regular meals and avoid spicy foods.
Diarrhoea:
Take large amount of fluids to avoid dehydration. ORS can also be used to prevent dehydration.
Vomiting:
Drink ice-cold drinks and eat light foods and avoid sweets.
Abdominal pain:
Place a warm water bottle on your abdomen or soak in a warm bath. Drink sufficient amount of water.
Headache:
Rest in a quiet, comfortable, and dark room with a cold or wet cloth on your temple.
AMBISOME 50MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.
AMBISOME 50MG should be used with caution in breastfeeding mothers. Consult your doctor before taking this medicine.
Do not drive or operate any machines, AMBISOME 50MG could affect your ability to drive or use machines safely.
AMBISOME 50MG should be used with caution if you are suffering from kidney failure or undergoing dialysis. Consult your doctor for advice.
Do not take if you are allergic (hypersensitive) to Amphotericin B.
Tell your physician if you have or had a condition, such as,
Tell your doctor if you are taking,
Drug | : | Amphotericin B |
Pharmacological Category | : | Antifungal Agent |
Therapeutic Indication | : | Life-threatening fungal infections, Leishmaniasis |
Dosage Forms | : | Injection, Topical gel |
Store at 2 - 8°C and keep out of reach of children.
How long will it take AMBISOME 50MG to be administered?
It usually takes 30 to 60 minutes. In case of high doses it may take up to 2 hours.
Does AMBISOME 50MG a fungicidal?
Yes, this medicine is fungicidal in nature, which kills the fungi.
Is AMBISOME 50MG testing dose needed?
Yes, testing dose is needed, to check if you have any allergic condition before starting the treatment.
1. KD Tripathi MD. General considerations. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 689.
2. Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 1424.
3. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. Page: 1571-1575.
4. Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page: 836-838.
5. Neil RH Stone, Tihana Bicanic, Rahuman Salim, and William Hope. Liposomal Amphotericin B: A review of the pharmacokinetics, pharmacodynamics, clinical experience and future directions. March, 2016. [Accessed May 25, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856207/
6. Gilead Sciences International Ltd. Electronic Medicines Compendium (EMC); [Revised Sep, 2020] [Accessed May 25, 2021] https://www.medicines.org.uk/emc/files/pil.1022.pdf
7. Teva Pharma B.V. Millmount Healthcare Limited. Electronic Medicines Compendium (EMC); [Revised Dec, 2020] [Accessed May 25, 2021] https://www.medicines.org.uk/emc/files/pil.5407.pdf
8. Cipla. [Revised Sep, 2013] [Accessed May 25, 2021] https://www.ciplamed.com/content/phosome-injection
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.