AMARYL M FORTE 2mg Tablet 10's

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Drug Information for AMARYL M FORTE 2mg Tablet 10's

What is Glimepiride + Metformin combination used for?

Glimepiride + Metformin combination is an oral anti-diabetic medicine, which is used for the treatment of high blood sugar levels in patients with type 2 diabetes. This combination should be used in conjunction with diet and exercise to improve glycaemic control.

Glimepiride + Metformin combination may also be prescribed for other conditions as determined by the doctor.

How does Glimepiride + Metformin combination work?

In Glimepiride + Metformin combination, Glimepiride belongs to the class of drugs called insulin secretagogues. It works by decreasing the blood glucose levels by stimulating the insulin release from the pancreatic cells. This drug also increases the insulin sensitivity at the target sites.

Metformin belongs to the class of drugs called biguanides, which acts by inhibiting the insulin production in the liver and decreasing the intestinal insulin absorption. Thus, it improves the insulin sensitivity by enhancing the peripheral glucose uptake.

How to take Glimepiride + Metformin combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Glimepiride + Metformin combination as prescribed by your doctor.

Swallow the tablet whole. Do not crush or chew the tablet. Take Glimepiride + Metformin combination with or without food.

If you miss a dose of Glimepiride + Metformin combination, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

The overdose symptoms of Glimepiride + Metformin combination may include:

  • Extreme weakness
  • Confusion
  • Tremors
  • Seizures

What are the drugs that interact with Glimepiride + Metformin combination?

Drugs that interact with Glimepiride + Metformin combination include the following:

  • Acebutolol
  • Acetaminophen
  • Albuterol
  • Captopril
  • Cyclosporine
  • Diatrizoate
  • Digoxin
  • Gatifloxacin
  • Indinavir
  • Iodipamide
  • Isoniazid
  • Metrizamide

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Glimepiride + Metformin combination?

The following are the most common side effects of Glimepiride + Metformin combination:

  • Abdominal pain
  • Fatigue
  • Mood swings
  • Nausea
  • Unusual weight gain
  • Photosensitivity reactions
  • Anaemia
  • Blurred vision

The following are the severe side effects and you may require immediate medical attention:

  • Dark-coloured urine
  • Lactic acidosis
  • Seizures
  • Yellow-coloured eyes

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions Glimepiride + Metformin combination?

  • Avoid using the medicine if you are allergic to Glimepiride + Metformin combination or similar drugs.
  • Avoid consumption of alcohol as it may worsen the side effects of Glimepiride + Metformin combination.
  • Do not exceed the dose more than what is prescribed.
  • Do not stop using the medication abruptly unless instructed by the doctor. Discontinuing the medication suddenly may cause the illness to return.
  • Do not drive or operate heavy machinery if Glimepiride + Metformin combination causes dizziness or blurred vision.
  • Avoid Glimepiride + Metformin combination during pregnancy or breastfeeding because the safe use of the drug is not yet established.

You are advised not to take Glimepiride + Metformin combination if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What special precautions should be followed while taking Glimepiride + Metformin combination?

  • Tell your doctor if you have any history of liver or kidney disorders.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • If you have to undergo any radiological procedures, you must inform the doctor about the usage of Glimepiride + Metformin combination.

Frequently Asked Questions about Glimepiride + Metformin

  1. How should Glimepiride + Metformin combination be stored?
  2. Glimepiride + Metformin combination should be stored at room temperature (25 – 30OC). Keep the medicine away from direct sunlight.

  3. Should I follow any special dietary instructions while taking Glimepiride + Metformin combination?
  4. Glimepiride + Metformin combination works effectively when taken with proper diet and exercise regimen.

  5. What are the other formulations of Glimepiride + Metformin combination available?
  6. Glimepiride + Metformin combination is available as tablet and capsule dosage forms.

  7. Do I need to be monitored for any laboratory parameters while taking Glimepiride + Metformin combination?
  8. Yes, regular monitoring of blood sugar level is advised while on Glimepiride + Metformin combination.

  9. Can I take Glimepiride + Metformin combination for type 1 diabetes?
  10. No, Glimepiride + Metformin combination is indicated only for patients with type 2 diabetes.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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