ALPHAGAN Z Eye Drops 5ml

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Drug Information for ALPHAGAN Z Eye Drops 5ml

    What is Brimonidine used for?

Brimonidine is prescribed to lower intraocular pressure in patients with open-angle glaucoma or high fluid pressure in the eyes. It reduces the amount of fluid produced by eyes, thereby decreasing the pressure inside the eyes. This eye drops is an alpha adrenergic receptor agonist that can lower the risk of blindness, loss of vision, or nerve damage. This medicine may also be used to treat other conditions as determined by your doctor.

How to take Brimonidine?

The dosage of Brimonidine prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

If your physician has instructed or directed you to apply Brimonidine medication in a regular schedule and you have missed a dose of this medicine, apply it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

Any medication taken in excess can have serious consequences. If you suspect an overdose of Brimonidine, seek medical attention immediately. However, overdose of this drug may not cause serious side effects.

What are the drugs that interact with Brimonidine?

  • Amitriptyline
  • Atenolol
  • Carbamazepine
  • Chlorpromazine
  • Clonidine
  • Codeine
  • Cyclobenzaprine
  • Diazepam
  • Digoxin
  • Diphenhydramine
  • Furazolidone
  • Isocarboxazid
  • Metoprolol
  • Moclobemide
  • Phenelzine
  • Phenobarbital
  • Phenothiazines
  • Procarbazine
  • Selegiline
  • Terazosin
  • Timolol
  • Tranylcypromine
  • Zolpidem

It may be noted that drugs other than those listed above may also interact with Brimonidine.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Brimonidine, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Brimonidine can interact with monoamine oxidase inhibitors, narcotic pain relievers, anti-anxiety medicines, antiseizure medicines, tricyclic antidepressants, antihistamines, high blood pressure drugs, beta blockers, muscle relaxants, and cold medications.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Brimonidine?

Like other medicines, Brimonidine can cause some side effects. If they do occur, the side effects of Brimonidine are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Brimonidine cannot be anticipated. If any side effects of Brimonidine develop or change in intensity, the doctor should be informed as soon as possible.

Brimonidine can cause side effects such as :

  • Puffy eyes
  • Headache
  • Blurred vision
  • Nausea
  • Insomnia
  • Burning
  • Stinging
  • Itching of eyes

Some of the serious side effects of this drug are:

  • Eye pain
  • Eye discharge
  • Irregular heart rate
  • Dizziness

Severe swelling in or around your eyes

This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are using Brimonidine.

What are the questions to ask your doctor before taking Brimonidine?

Is it possible for me to apply Brimonidine with other drugs?
Should certain beverages, foods and other products be avoided when I apply Brimonidine?
What are the possible drug interactions of Brimonidine?
How will Brimonidine work in my body?
How should Brimonidine be applied?
How to reduce the risk of Brimonidine drug interactions and side effects?

What should you tell your doctor before taking Brimonidine?

Before using Brimonidine, inform your doctor if you are suffering from high blood pressure, kidney or liver disease, and heart disease. It is important to inform your doctor if you are pregnant or nursing your baby. If you are wearing contact lenses, then it should be removed prior to the application of the eye drops. Caution should be exercised when you engage in activities that require mental alertness.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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