INTRODUCTION
ALGIC PLUS EYE DROPS is a combination of Ketorolac and Ofloxacin which belongs to the group of medicines called Analgesics and Antibiotics respectively. It is used to treat and prevent eye inflammation and infection. It helps in reducing eye pain, redness, itching and burning/stinging sensation following eye surgery (such as cataract surgery or corneal refractive surgery). It is typically used in eye conditions which involves the risk of both eye inflammation and infection such as during injury or post-surgery.
ALGIC PLUS EYE DROPS is for ophthalmic use only. Gently instil few drops of the medicine into the affected eyes. If you wear soft contact lenses, remove the lens before applying ALGIC PLUS EYE DROPS and wait for at least 15 minutes before reinsertion.
Before using ALGIC PLUS EYE DROPS inform your doctor if you have severe viral or fungal ear/eye infections. You must also inform your doctor if you have any eye defects, dry eyes, diabetes, stomach ulcers, joint pain or low blood potassium or magnesium levels as a precaution.
Do not use ALGIC PLUS EYE DROPS if you are pregnant or breastfeeding. The most common side effects of using ALGIC PLUS EYE DROPS are temporary burning sensation and blurring of vision, mild eye itching, redness and irritation, dry eyes, headache and blurred vision. Consult your doctor if any of these side effect worsens.
USES OF ALGIC PLUS EYE DROPS
- Treats and prevents eye infection and inflammation
- Reduces eye pain, redness, itching or burning/stinging sensation following eye surgery
HOW ALGIC PLUS EYE DROPS WORKS
ALGIC PLUS EYE DROPS contains two medicines namely, Ketorolac and Ofloxacin. Ketorolac is a pain-relieving medication. It blocks the release of certain chemicals in the body (such as prostaglandins) that causes inflammation, redness and swelling. When applied topically on the eyes, it reduces eye redness, soreness, pain, itching and swelling.
Ofloxacin is an antibiotic. When applied topically on the eyes, it kills the susceptible bacteria that causes eye infection. Collectively, this medicine reduces eye inflammation and pain and prevents the risk of eye infections.
DIRECTIONS FOR USE
Use ALGIC PLUS EYE DROPS as advised by your physician. It is for ophthalmic use only. Tilt your head slightly backwards and gently pull your lower eyelid. Instil few drops of this medicine into the eyes and close your eyes for 2 minutes. Repeat the same for the other eye if required. If you wear soft contact lenses, remove the lens before applying ALGIC PLUS EYE DROPS and wait for at least 15 minutes before reinsertion.
Wash your hands before and after application. Leave a time gap of 5 minutes before applying other medicines on your eyes. Do not touch the tip of the container with your eyes, eyelids, areas around your eyes, ears or fingers, to avoid contamination.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.
SIDE EFFECTS OF ALGIC PLUS EYE DROPS
COMMON
- burning sensation following application
- mild eye pain, itching, redness or irritation
- swelling of the eyes or eyelids
- dry eyes
- headache
- increased pressure in the eye
- blurred and/or diminished vision
UNCOMMON
- watery eyes
- abnormal eye sensation
RARE
Stop using ALGIC PLUS EYE DROPS and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, tongue causing difficulty in breathing or swallowing)
- severe eye pain, redness, irritation and vision changes
- severe skin reactions causing skin rashes, with red-target spots or circular patches on the skin, blistering and peeling of skin with fever
HOW TO MANAGE SIDE EFFECTS
Burning or stinging of eyes:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops or television. Wear protective eyeglasses while going outdoors.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
WARNING & PRECAUTIONS
PREGNANCY
ALGIC PLUS EYE DROPS is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using it.
BREASTFEEDING
ALGIC PLUS EYE DROPS is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before using it.
DRIVING AND USING MACHINES
Do not drive or operate any heavy tools or machinery if you experience blurred vision or light-headedness after using ALGIC PLUS EYE DROPS.
ALLERGY
Do not use ALGIC PLUS EYE DROPS if you are allergic to Ketorolac, Ofloxacin or to any other quinolone antibiotics (such as ciprofloxacin) or non-steroidal anti-inflammatory drugs (such as aspirin).
LUNGS
ALGIC PLUS EYE DROPS should be used with caution in patients who previously developed asthma symptoms while taking an analgesic medicine. Kindly, inform your doctor before using it.
HEART DISEASE
ALGIC PLUS EYE DROPS should be used with caution in patients with heart problems such as prolonged QT interval, slow heartbeat, heart failure or history of heart attack. Therefore, consult your doctor before using it.
OTHERS
Before using ALGIC PLUS EYE DROPS inform your doctor if you:
- wear soft contact lenses
- have a viral or bacterial infection in the eyes
- have stomach ulcers or any conditions that may cause internal bleeding
- have diabetes
- have rheumatoid arthritis (joint inflammation)
- have dry eyes or corneal problems
- have any eye defects
- have any ulceration on the surface of eyes
- have salt imbalance in your body
- have low potassium or magnesium levels in blood
Use in pediatrics:
ALGIC PLUS EYE DROPS is not recommended for use in children and adolescents (aged below 18 years) unless prescribed by a physician. Therefore, consult your doctor before administration.
Use in geriatrics:
ALGIC PLUS EYE DROPS should be used with caution in elderly patients. Therefore, consult your doctor before using it.
INTERACTIONS
A. Drug-Drug interactions:
Before using ALGIC PLUS EYE DROPS, inform your doctor if you are taking any of the following medicines such as:
- medicines used to treat abnormal heart rhythm (such as quindine, hydroquindine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide)
- medicines used to treat depression (such as amitriptyline, imipramine)
- macrolide antibiotics (used to treat bacterial infections) such as erythromycin, clarithromycin, azithromycin
- medicines used to treat psychiatric disorders (such as chlorpromazine, haloperidol, thioridazine etc.)
Overdosage:
If you or anyone else accidentally used excessive amount of this medicine, rinse your eyes or ears with warm water. If still irritation persists, consult your doctor for advice. If you or anyone else accidentally swallowed this medicine, consult your doctor immediately.
SYNOPSIS
| Drug | : | Ketorolac, Ofloxacin |
| Pharmacological Category | : | Non-Selective COX Inhibitors, Fluroquinolones |
| Therapeutic Indication | : | Eye inflammation and infection |
| Dosage Forms | : | Eye Drops |
MORE INFORMATION
- Keep ALGIC PLUS EYE DROPS out of reach of children
- Store ALGIC PLUS EYE DROPS at room temperature
- Do not use this medicine after 4 weeks of its opening, even if it contains some left-over medicine
FAQs ABOUT ALGIC PLUS EYE DROPS
Q: What is the use of ALGIC PLUS EYE DROPS?
A: ALGIC PLUS EYE DROPS is used to treat and prevent eye inflammation and infection. It helps in reducing eye pain, redness, itching and burning/stinging sensation following eye surgery (such as cataract surgery or corneal refractive surgery).
Q: How ALGIC PLUS EYE DROPS works?
A: ALGIC PLUS EYE DROPS blocks the release of certain chemicals in the body (such as prostaglandins) that causes pain, inflammation and swelling of the eyes. It also kills the susceptible bacteria that causes eye infection. Collectively, this medicine reduces inflammation and infection of the eyes.
Q: How to use ALGIC PLUS EYE DROPS?
A: Use ALGIC PLUS EYE DROPS as advised by your physician. It is for external use only. Instil few drops of this medicine into the affected eyes. Repeat the same for the other eye if required.
Q: How long does it take for ALGIC PLUS EYE DROPS to work?
A: It may take around 10-15 minutes for ALGIC PLUS EYE DROPS to start showing its effects. However, this period may vary from person-to-person depending upon the dose that is administered.
Q: Can the use of ALGIC PLUS EYE DROPS cause blurred vision?
A: Yes. ALGIC PLUS EYE DROPS may cause blurred vision after application in some individuals, although not everybody gets them. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Q: Can I use other eye medicines while using ALGIC PLUS EYE DROPS?
A: Avoid concomittant use of any eye medicines while using ALGIC PLUS EYE DROPS without consulting your doctor.
Q: What are the side effects of ALGIC PLUS EYE DROPS?
A: The most common side effects of using ALGIC PLUS EYE DROPS are temporary burning sensation and blurring of vision, mild eye itching, redness and irritation, dry eyes, headache and blurred vision. Consult your doctor if any of these side effect worsens.
Q: Can I use ALGIC PLUS EYE DROPS while wearing contact lenses?
A: If you wear soft contact lenses, remove the lens before applying ALGIC PLUS EYE DROPS and wait for at least 15 minutes before reinsertion.
Q: Can I use ALGIC PLUS EYE DROPS without consulting my doctor?
A: No. ALGIC PLUS EYE DROPS is a prescription medicine which should be used only if prescribed by the physician.
Q: Can I drive or ride a bike after using ALGIC PLUS EYE DROPS?
A: Do not drive if you experience blurred vision after using ALGIC PLUS EYE DROPS.
Q: What if I miss a dose of ALGIC PLUS EYE DROPS?
A: If you missed a dose of ALGIC PLUS EYE DROPS, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose of ALGIC PLUS EYE DROPS to compensate the missed dose.
Q: Can I stop using ALGIC PLUS EYE DROPS once my symptoms subside?
A: No. Do not stop using this medicine without consulting your doctor as it may make your symptoms to re-appear. Therefore, use this medicine consistently for the duration instructed by your doctor to achieve better results.
REFERENCES
1. KD. Tripathi. Nonsteroidal Antiinflammatory Drugs and Antipyretic-Analgesics. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 202, 709 & 713.
2. Derrick B. Graham; Jayson Tripp. Ofloxacin. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2022. [Accessed on 17th January 2023] https://www.ncbi.nlm.nih.gov/books/NBK549837/
3. Helga P Sandoval, Luis E Fernández de Castro, David T Vroman, and Kerry D Solomon. A review of the use of ketorolac tromethamine 0.4% in the treatment of post-surgical inflammation following cataract and refractive surgery. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. December 2007. [Accessed on 17th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704525/
4. Allergan Pharmaceuticals (Pty) Ltd. ACULAR 0,4 %, 4 mg/ml ophthalmic solution Ketorolac tromethamine. [Revised in April 2021]. [Accessed on 17th January 2023] https://allergan-web-cdn-prod.azureedge.net/allergansouthafrica/allergansouthafrica/media/allergan-south-africa/products/za-pil-acular-0,4-9437x-nat-en-2021-04-14.pdf
5. Allergan Pharmaceuticals Ireland. ACULAR®0.5% (w/v) Eye Drops, Solution Ketorolac trometamol. Electronics Medicines Compendium. [Revised in February 2022]. [Accessed on 17th January 2023] https://www.medicines.org.uk/emc/files/pil.855.pdf
6. Allergan Pharmaceuticals Ireland. EXOCIN® 0.3% w/v Eye drops, solution Ofloxacin. Electronics Medicines Compendium. [Revised in February 2022]. [Accessed on 17th January 2023] https://www.medicines.org.uk/emc/files/pil.1353.pdf
7. Allergen India Pvt Ltd. Ketoflox Ketorolac Tromethamine+Ofloxacin Ophthalmic solution. [Accessed on 17th January 2023] https://allergan-web-cdn-prod.azureedge.net/allerganindia/allerganindia/media/allergan-india/products/ketoflox.pdf
8. Central Drugs Standard Control Organization. Ketorolac Tromethamine 5mg + Ofloxacin 3mg per ml Eye drops. July 2005. [Accessed on 17th January 2023] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
9. Innovative Pharmaceuticals Pvt Ltd. Oflotag-K Eye Drops. [Accessed on 17th January 2023] https://www.innovativepharma.in/product/oflotag-k-eye-drops/
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