INTRODUCTION

ALFUMAC 10MG TABLET contains Alfuzosin which belongs to the group of medicines called Alpha-1-blockers. It is used to provide relief from moderate to severe symptoms of benign prostatic hyperplasia in affected individuals.

Benign prostatic hyperplasia is a non-cancerous condition that increases the size of the prostate and it is generally characterized by symptoms such as increased urinary frequency, unusual urine color/smell, urinary urgency, weak/interrupted urine stream, and pain after urination/ejaculation.

ALFUMAC 10MG TABLET is not recommended for use in patients who are allergic to alfuzosin or equivalent substances (such as terazosin and doxazosin). It is also not recommended for use in patients with orthostatic hypotension (low blood pressure while standing up from a sitting or lying position), liver problems and should be used with caution in patients with kidney problems (such as mild, moderate and severe kidney problems).

ALFUMAC 10MG TABLET is not recommended for use in pregnant or breastfeeding women as it is used only in men. It is also not recommended for use in children and adolescents (aged below 18 years) and it should be used with caution in elderly patients (aged 65 and above).

The most common side effects of taking ALFUMAC 10MG TABLET are dizziness, headache, nausea, stomach pain, weakness and tiredness. Consult your doctor if any of the side effects worsens.   

USES OF ALFUMAC 10MG TABLET

• Relieves moderate to severe symptoms of benign prostatic hyperplasia  

HOW ALFUMAC 10MG TABLET WORKS

ALFUMAC 10MG TABLET works by binding and inhibiting a receptor (alpha 1-adrenergic receptor) in the lower urinary tract, which results in the relaxation of muscles around the bladder, thus facilitating urine to flow more easily and thereby providing relief from symptoms of benign prostatic hyperplasia.

DIRECTIONS FOR USE

Take ALFUMAC 10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF ALFUMAC 10MG TABLET

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Nausea:

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.

Diarrhoea:

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking ALFUMAC 10MG TABLET inform your doctor if you are taking any of the following medicines:   

• other alpha-blockers (medicines used to treat hypertension and benign prostatic hyperplasia) Ex. doxazosin, indoramin, prazosin, terazosin, tamsulosin, phenoxybenzamine
• antihypertensives (medicines used to treat high blood pressure) Ex. captopril, ramipril
• nitrates such as nitroglycerin (used to treat chest pain (angina))
• ketoconazole, itraconazole (used to treat fungal infections)
• ritonavir medicine (used to treat HIV infection)
• medicines used to treat bacterial infections (Ex. clarithromycin, telithromycin)
• medicines used to treat depression (Ex. nefazodone)
• general anesthetics such as propofol (medicines used to provide unconsciousness during surgery)

Overdosage:

If you or anyone else accidentally take too much of ALFUMAC 10MG TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep ALFUMAC 10MG TABLET out of reach of children
• Store the medicine at room temperature

FAQs ABOUT ALFUMAC 10MG TABLET

What is ALFUMAC 10MG TABLET used for?

ALFUMAC 10MG TABLET is used to provide relief from moderate to severe symptoms of benign prostatic hyperplasia which is a non-cancerous condition that increases the size of the prostate and it is generally characterized by symptoms such as increased urinary frequency, unusual urine color/smell, urinary urgency, weak/interrupted urine stream, and pain after urination/ejaculation.

Can ALFUMAC 10MG TABLET be used in children?

No, ALFUMAC 10MG TABLET is not recommended for use in children and adolescents (below 18 years of age). If ALFUMAC 10MG TABLET is accidentally ingested by a child or adolescent, go to the hospital immediately and consult the doctor for further management.

What are the common side effects of ALFUMAC 10MG TABLET?

The most common side effects of taking ALFUMAC 10MG TABLET are dizziness, headache, nausea, stomach pain, weakness and tiredness. Consult your doctor if any of the side effects worsens.

How does ALFUMAC 10MG TABLET work?

ALFUMAC 10MG TABLET works by binding and inhibiting a receptor (alpha 1-adrenergic receptor) in the lower urinary tract, which results in the relaxation of muscles around the bladder, thus facilitating urine to flow more easily and thereby providing relief from symptoms of benign prostatic hyperplasia.

Is ALFUMAC 10MG TABLET safe to use in patients with kidney problems?

ALFUMAC 10MG TABLET should be used with caution in patients with kidney problems such as mild, moderate and severe kidney problems. Your doctor may regularly monitor your kidney function test to prevent any unusual effects. Consult your doctor before taking ALFUMAC 10MG TABLET.

REFERENCES

1. KD. Tripathi. Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 142.

2. Madhu S. Agrawal, Abhishek Yadav, Himanshu Yadav, Amit K. Singh, Prashant Lavania and Richa Jaiman. A prospective randomized study comparing alfuzosin and tamsulosin in the management of patients suffering from acute urinary retention caused by benign prostatic hyperplasia. NIH National Library of Medicine. National center for biotechnology information. Pubmed Central. December 2009. [Accessed on 26th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128060/

3. Sanofi. The Efficacy, Onset of Effect, and Safety of Alfuzosin Once Daily in the Treatment of Lower Urinary Tract Symptoms of Benign Prostatic Hyperplasia: A Randomized, Placebo-Controlled Trial Using an Acute International Prostate Score (ALF-ACUTE). Clinicaltrials.gov. [Revised in October 2007] [Accessed on 26th April 2022] https://clinicaltrials.gov/ct2/show/NCT00540891

4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 26th April 2022] https://www.medicines.org.uk/emc/files/pil.7047.pdf

USEFUL DIAGNOSTIC TESTS

• Prostate-specific antigen (PSA) blood test
• Urine analysis