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INTRODUCTION

ALDACTONE F is a combination of Spironolactone and Frusemide which belongs to the group of medicines called Diuretics. It helps to reduce fluid build-up (edema) in the body. Edema is a type of swelling or puffiness of body parts caused due to excessive accumulation of fluid (water) in the body. These extra fluids can cause swollen ankles, shortness of breath and can make you feel more tired than usual. It can also put extra strain on your heart, blood vessels, lungs, kidneys, or liver.

Spironolactone is a potassium sparing diuretic and frusemide is a loop diuretic. They act by removing the excess water and certain electrolytes (sodium and chloride) from the body in the form of urine. Unlike other diuretics, ALDACTONE F retains potassium in the body which prevents the risk of developing hypokalaemia (low blood potassium levels).

Before taking ALDACTONE F inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you are severely dehydrated or have diabetes, gout, prostate problems, or low blood pressure which makes you feel dizzy while standing up or changing position.

During treatment with ALDACTONE F, avoid consuming potassium rich diet or potassium supplements, as it may further increase the levels of potassium in your body.

ALDACTONE F is not recommended for use in patients with severe low sodium levels in their blood. It is also not suitable for use in pregnant or breastfeeding women due to increased risk of side effects.

ALDACTONE F may alters the levels of electrolytes in your body and may make you feel dizzy or tired very easily. To avoid this, your doctor would closely monitor your serum electrolyte levels and increase or decrease the dose of ALDACTONE F accordingly.

The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, muscle weakness, increased urination, or impotence. Consult your doctor if any of the side effect bothers you.

USES OF ALDACTONE F

  • Treats edema (fluid retention)

HOW ALDACTONE F WORKS

ALDACTONE F acts by removing the excess water and certain electrolytes (sodium and chloride) from the body in the form of urine while simultaneously maintaining the levels of potassium in the body.

DIRECTIONS FOR USE

Take ALDACTONE F as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It is taken preferably with meals. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Avoid taking ALDACTONE F at night as it could affect your sleep. Do not stop taking ALDACTONE F unless your doctor tells you to stop.

SIDE EFFECTS OF ALDACTONE F

COMMON

  • headache, dizziness
  • nausea, vomiting
  • general weakness
  • increased urination
  • excessive thirst
  • impotence, reduced sex drive
  • breast enlargement in men
  • sensation of tingling and numbness

UNCOMMON

  • loss of bladder control
  • loss of hearing
  • leg cramps

RARE

  • ringing in the ears
  •  inflammation of blood vessels

Stop taking ALDACTONE F and contact your doctor immediately if you experience any of the following side effects:

  • signs of allergic reaction (such as skin rash, itching severe blistering of the skin around the lips, eyes, mouth, nose and genitals, skin sensitivity, fever, swollen ankles, inflammation of the kidneys, shock, cold or pale skin, difficulty in breathing, fast heartbeat)
  • signs of pancreatitis (such as severe stomach pain or back pain)
  • increased infections and tendency to bruise more easily, feeling weak or tired more than usual
  • signs of dehydration (such as excessive thirst, feeling dizzy or light-headed, fainting, headache, confusion, joint pains, muscle weakness or spasms, stomach upsets or uneven heartbeats)
  • signs of liver problems (such as yellowing of the skin or eyes, dark urine)
  • feeling dizzy or faint

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take ALDACTONE F with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely if you feel dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

WARNING & PRECAUTIONS

PREGNANCY

ALDACTONE F is generally not recommended for use in pregnant women. However, consult your doctor before taking it.

BREASTFEEDING

ALDACTONE F is generally not recommended for use in breastfeeding women. However, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy or unwell after taking ALDACTONE F.

ALCOHOL

Avoid consumption of alcohol while taking ALDACTONE F as it might make you feel more dizzy.

KIDNEY

ALDACTONE F is not recommended for use in patients with severe kidney diseases. It should be used with caution in patients with other minor kidney problems. Therefore, consult your doctor before taking it.

LIVER

ALDACTONE F is not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take ALDACTONE F if you are allergic to Frusemide, Spironolactone, or sulphonamides (Ex. sulfadiazine).

HEART DISEASE

ALDACTONE F should be used with caution in patients with heart diseases (such as low blood pressure). Therefore, consult your doctor before taking it.

OTHERS

ALDACTONE F is not recommended for use if you:

  • have a low blood volume (hypovolemia) or severely dehydrated
  • pass scanty urine or no urine at all
  • have low or high levels of sodium or potassium in the blood
  • have Addison's disease (problems with adrenal glands)

Before taking [GBNKEYWORD inform your doctor if you:

  • feel dizzy upon standing up or changing position
  • have diabetes
  • have difficulty in passing urine
  • have prostate cancer or other problems in prostate
  • have gout

Use in pediatrics:

ALDACTONE F is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

Use in geriatrics:

ALDACTONE F should be used with caution in elderly people (aged above 65 years) especially in patients undergoing treatment for mental illness. Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interaction:

Before taking ALDACTONE F, inform your doctor if you are taking any of the following medicines such as:

  • medicines that can change the amount of potassium in your blood such as potassium supplements (Ex. potassium chloride) or potassium sparing diuretics (Ex. triamterene and amiloride)
  • medicines used to control elevated blood pressure (such as losartan, candesartan, irbesartan, ramipril, enalapril, perindopril)
  • medicines used for relaxing muscles during surgery (Ex. vecuronium and rocuronium)
  • medicines used to treat diabetes (Ex. metformin, glimepiride)
  • theophylline (a medicine used for asthma)
  • phenytoin, carbamazepine (medicines used to treat fits or epilepsy)
  • lithium, risperidone (medicines used for mental illnesses)
  • medicines used to treat certain forms of cancer (Ex. cisplatin, aminoglutethimide, abiraterone)
  • digoxin (a medicine used to treat abnormal heart rate)
  • non-steroidal anti-inflammatory drugs (used for pain relief) such as indomethacin, aspirin, ibuprofen, or ketoprofen
  • ciclosporin (a medicine used to prevent graft rejection)
  • methotrexate (a medicine used for skin cancer, arthritis, or bowel diseases)
  • carbenoxolone (used to treat ulcers of the food-pipe)
  • corticosteroids (used to treat inflammation) Ex. prednisolone
  • probenecid (a medicine used to treat gout)
  • cholestyramine (a medicine used to control blood cholesterol levels
  • medicines used to treat bacterial infections (Ex. trimethoprim, sulfamethoxazole, ceftriaxone, cefazolin, gentamycin, streptomycin, amikacin, neomycin, netilmicin, tobramycin, vancomycin)
  • bendroflumethiazide (another diuretic used to treat edema)
  • medicines used as injections before X-ray examinations (Ex. iodine)
  • medicines used to treat asthma (such as salbutamol, terbutaline, salmeterol, formoterol or bambuterol)
  • reboxetine (a medicine used to treat depression)
  • amphotericin (a medicine used to treat fungal infections)
  • medicines used to treat constipation such as laxatives (Ex. bisacodyl, Senna)
  • liquorice (a medicine used in cough preparations)

Overdosage:

If you or anyone else accidentally took more ALDACTONE F, consult your doctor immediately. Symptoms of overdosage might include increased thirst, dryness of mouth, muscle pain or cramps, nausea or vomiting, weak or uneven heartbeat, feeling dizzy, weak or sleepy.

SYNOPSIS

Drug :  

Spironolactone, Frusemide

Pharmacological Category :  

Potassium sparing diuretics, Loop diuretics

Therapeutic Indication :  

Edema (fluid retention)

Dosage Forms :  

Tablet

MORE INFORMATION

  • Keep ALDACTONE F out of reach of children
  • Store ALDACTONE F at room temperature

FAQs ABOUT ALDACTONE F

What is the use of ALDACTONE F?

ALDACTONE F is a prescription medicine used to treat edema associated with various heart, liver, or kidney problems. It removes excess water accumulated in the body via urine.

Can I take ALDACTONE F daily?

Take ALDACTONE F as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take ALDACTONE F every day or not.

What are the possible side effects of ALDACTONE F?

The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, muscle pain and increased urination. It may also cause impotence in men. Consult your doctor if any of the side effect bothers you. Also inform your doctor immediately if you experience irregular heartbeat, joint pain, muscle pain, extreme dizziness or fainting or severe stomach pain after taking ALDACTONE F.

What is the best time to take ALDACTONE F?

It is advisable to take ALDACTONE F in the morning preferably after meals. Avoid taking ALDACTONE F at night as it may make urinate more at night which may affect your sleep. However, consult your doctor regarding the time of administration of ALDACTONE F.

How long does it take for ALDACTONE F to show the results?

It may take a few weeks for ALDACTONE F to show the results, and so take ALDACTONE F regularly as advised by your physician to see the optimum results.

Can ALDACTONE F cause dizziness?

Yes. ALDACTONE F may cause dizziness due to the loss of fluids from the body. To avoid this, keep yourself hydrated by drinking plenty of fluids. Avoid driving or operating any heavy tools or machines if you feel dizzy. Consult your doctor if you experience extreme dizziness.

Can I consume alcohol while taking ALDACTONE F?

Avoid consumption of alcohol while taking ALDACTONE F as it might make you feel dizzy or faint even when you change posture.

Do I have any food restrictions while taking ALDACTONE F?

Avoid foods rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes containing potassium while taking ALDACTONE F. It is because ALDACTONE F can reabsorb potassium in the kidneys, and so additionally consumption of potassium rich foods or supplements may further increase the levels of potassium in the blood.

Do we need any laboratory investigations while taking ALDACTONE F?

Yes. ALDACTONE F may alter the electrolyte balance in your body, and make you feel tired or dehydrated very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and increase or decrease the dose of this medicine accordingly.

Can ALDACTONE F reduce my weight?

ALDACTONE F does not have any impact on reducing your weight. But, due to removal of excess water from the body, you may experience a slight reduction in body weight.

Can I take ALDACTONE F to reduce my postpartum belly?

No. ALDACTONE F is not indicated for use in postpartum women. Do not take ALDACTONE F unless your doctor has prescribed it. It is not advisable to breastfeed while taking ALDACTONE F. Consult your doctor before taking ALDACTONE F.

Can ALDACTONE F cause cancer?

No. Research does not suggest any risk of cancer while taking [GBNEYWORD]. If you are doubtful consult your doctor for advice.

Can I take ALDACTONE F on my own?

No. ALDACTONE F is a prescription medicine. It should be used only when prescribed by a physician. Do not take ALDACTONE F on your own without consulting your doctor.

Can ALDACTONE F affect sense of hearing?

Yes. Some rare cases of hearing loss have been reported with the use of ALDACTONE F. This condition is often reversible after discontinuing therapy with ALDACTONE F. However, consult your doctor immediately if you experience any disturbances in the sense of hearing.

Can the use of ALDACTONE F cause frequent urination?

Yes. ALDACTONE F may cause frequent urination. It tends to excrete the accumulated fluid from the body in the form of urine. As a result, you may experience an increase in tendency to urinate. If this bothers you, contact your doctor.

Can the use of [GNKEYWORD] make me more tired?

Yes. ALDACTONE F may make you feel tired easily because it removes the excess fluids from the body. This reduces your energy levels and make you feel very tired. To avoid this, keep yourself hydrated by drinking plenty of fluids. If you experience extreme tiredness that hinders your daily activities, consult your doctor for advice.

REFERENCES

1. K.D. Tripathi. Diuretics. Essentials of Medical pharmacology. Seventh edition. 2013. Page no – 579-582 & 587.

2. A.E.Birbari, M.M.Daouk, S.Mukaddam-Daher. Efficacy and safety of lasilactone, a new combination diuretic, in essential hypertension. ScienceDirect. November 2002.  [Accessed on 11th April 2022] https://www.sciencedirect.com/science/article/abs/pii/0306362387900322?via%3Dihub

3. Sanofi. Electronic Medicines Compendium (EMC) [Revised in March 2022] [Accessed on 9th April 2022] https://www.medicines.org.uk/emc/files/pil.907.pdf

4. G.D. Searle U.S. Food & Drug Administration [Revised on March 2018] [Accessed on 9th April] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/012151s075lbl.pdf

5. Accord Healthcare Limited Electronic Medicines Compendium (EMC) [Revised on March 2020] [Accessed on 9th April] https://www.medicines.org.uk/emc/files/pil.6012.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney function test

PRODUCT DETAILS

    Country Of Origin
    India
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ALDACTONE F Tablet 10's

ALDACTONE F Tablet 10's Mkt: Rpg Life Sciences Ltd

M.R.P.: Rs.81.20
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