AFFLU 150 Tablet 1's

Fungal Rx required

Best Price* ₹ 7.20 MRP ₹ 9.00
(Inclusive of all taxes) *1 Tablet(s) in a Strip * Mkt: Apostle Remedies * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

AFFLU 150 contains Fluconazole which belongs to the group of medicines called Anti-fungal agents. It is used to treat various fungal infections such as systemic candidiasis (fungal infection affecting the blood, brain, heart, eyes or other parts of the body), mucosal candidiasis (fungal infection affecting the mouth, throat or denture sore mouth), cryptococcosis (fungal infection mainly affecting the lungs and brain), vaginal candidiasis (fungal infection of the vagina and tissues at the opening of the vagina (vulva)).

Also, it prevents fungal infections in immunocompromised patients considered at risk due to HIV infection or low white blood cell count after cytotoxic chemotherapy, radiotherapy or bone marrow transplant.

Before taking AFFLU 150, inform your doctor if you have liver, kidney or heart problems, abnormal levels of potassium, calcium or magnesium in your blood, are prone to develop severe skin reactions and have a history of adrenal insufficiency.

AFFLU 150 is not recommended for use in pregnant and breastfeeding women unless clearly advised by the doctor. AFFLU 150 should be used with caution in children and adolescents (from birth to 17 years of age). It should be used with caution in elderly patients particularly with renal impairment.

The most common side effects of taking AFFLU 150 are headache, nausea, vomiting diarrhoea, abdominal pain and indigestion. Consult your doctor if any of the side effects get worse.

USES OF AFFLU 150

  • Treats various fungal infections (such as systemic candidiasis, mucosal candidiasis, cryptococcosis and vaginal candidiasis)
  • Prevents fungal infection in immunocompromised patients

HOW AFFLU 150 WORKS

AFFLU 150 works by stopping the action of an enzyme called ergosterol, which is an integral part of the fungal cell membrane to increase its cellular permeability. Thereby, making the cell membrane more permeable and stopping the fungal growth. This type of action is helpful in treating and preventing various fungal infections.

DIRECTIONS FOR USE

Take AFFLU 150 as advised by your physician. Swallow AFFLU 150 with a glass of water and do not chew or crush the medicine. The correct dose and duration for you will be decided by the doctor depending upon your age, body weight and type of infection.

SIDE EFFECTS OF AFFLU 150

COMMON

  • headache
  • nausea, vomiting
  • diarrhoea
  • abdominal pain
  • indigestion
  • acne

UNCOMMON

  • seizures, dizziness, altered nerve sensation and taste
  • skin rash with itching, abnormal odour from the skin and dry skin
  • abnormal changes in vision
  • constipation, flatulence and dry mouth
  • thirst, tiredness, body pain and fever
  • weakness, general feeling of discomfort, rigour
  • pharyngitis, herpes simplex viral infection
  • loss of appetite
  • back, muscle pain, muscle spasm
  • renal pain head spinning sensation (vertigo)
  • insomnia and nervousness
  • muscle overactivity (hypertonia)
  • increased urine output
  • abnormal or heavy vaginal bleeding, painful menses, vaginal discharge and disorder, uterine spasm, female sexual dysfunction  
  • hot flushes, excess sleepiness
  • deafness, increased blood pressure, low oxygen levels, intolerance to oral intake, inflamed and sore mouth (in children)

RARE

  • allergic reactions
  • low white blood cells and platelet count  
  • hair loss
  • damage to the liver causing liver failure, hepatitis and necrosis
  • skin reactions (like steven johnson syndrome and toxic epidermal necrolysis)
  • shaking
  • change in heart rate or rhythm

Stop taking AFFLU 150 and contact your doctor immediately if you experience any of the following side effects:

  • sudden wheezing, difficulty in breathing or tightness in the chest, swelling of eyelids, face or lips, itching all over the body, reddening of the skin or itchy red spots
  • skin rash that causes blistering in the mouth and tongue
  • signs of liver problems (tiredness, loss of appetite, vomiting and yellowing of the skin or whites of the eyes)
  • signs of DRESS syndrome or drug hypersensitivity syndrome (widespread rash, high body temperature and enlarged lymph nodes)

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lot of fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own to treat diarrhoea without consulting your doctor.

Nausea or vomiting:

Stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.

Stomach pain:

Try to take rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress-free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Dizziness:

Lie down until the dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

AFFLU 150 is not recommended for use during pregnancy unless considered clearly necessary. Consult your doctor before taking AFFLU 150.

BREASTFEEDING

AFFLU 150 is not recommended for use in breastfeeding women after repeated use or after high dose of this medicine. You may continue breast-feeding after single dose of AFFLU 150. Consult your doctor before taking AFFLU 150.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you experience dizziness or fits after taking AFFLU 150.

KIDNEY

AFFLU 150 should be used with caution in patients with kidney dysfunction. Consult your doctor before taking AFFLU 150.

LIVER

AFFLU 150 should be used with caution in patients with liver dysfunction. Consult your doctor before taking AFFLU 150.

ALLERGY

AFFLU 150 is not recommended for use if you are allergic to fluconazole or other azole antifungals (such as itraconazole or posaconazole).

HEART DISEASE

AFFLU 150 should be used with caution in patients with heart rhythm problems. Consult your doctor for advice before taking AFFLU 150.

OTHERS

AFFLU 150 is not recommended for use if you:

  • rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption

Before taking AFFLU 150, inform your doctor if you:

  • have abnormal levels of potassium, calcium or magnesium in your blood
  • are prone to develop severe skin reactions (itching, reddening of the skin or difficulty in breathing)
  • have a history of adrenal insufficiency
  • have no improvement in fungal infection

Use in Pediatrics:

AFFLU 150 should be used with caution in children and adolescents (from birth to 17 years of age). Consult the child’s doctor for advice before administration of AFFLU 150 to your child.

Use in Geriatrics:  

AFFLU 150 should be used with caution in elderly patients particularly with renal impairment. Your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking AFFLU 150.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking AFFLU 150, inform your doctor, if you are taking any of the following medicines:

  • medicines used to treat diabetes medicines (Ex. glyburide, tolbutamide, glipizide, chlorpropamide)
  • medicines used to treat high blood pressure (Ex. hydrochlorothiazide, nifedipine, isradipine, amlodipine, felodipine and losartan)
  • medicines used as blood thinners (Ex. warfarin)
  • medicines used to use to prevent rejection of organ transplants (Ex. cyclosporine, tacrolimus, sirolimus)
  • rifampicin or rifabutin (used to treat tuberculosis)
  • astemizole, terfenadine (used to treat a certain type of allergies)
  • medicines used to control seizures /fits (Ex. phenytoin or carbamazepine)
  • theophylline (used to control asthma)
  • cisapride (used to treat heartburn)
  • medicines used to treat heart diseases (Ex. quinidine, amiodarone)
  • medicines used to treat depression (Ex. amitriptyline, nortriptyline)
  • pimozide (used to control motor or verbal tics)
  • amphotericin B, voriconazole (medicine for treating various fungal infections)
  • erythromycin (used for treating bacterial infections)
  • cyclophosphamide, medicines used for treatment of cancer (Ex. vincristine or vinblastine)
  • alfentanil, fentanyl (used as general anesthetic)
  • halofantrine (for treating malaria)
  • medicines used to treat high cholesterol levels (Ex. atorvastatin, simvastatin and fluvastatin)
  • medicines used to treat painful conditions with inflammation (Ex. celecoxib, ibuprofen and naproxen)
  • prednisone (used to treat inflammatory disorders)
  • antiviral medications used to treat HIV infection (Ex.  saquinavir, zidovudine)
  • tofacitinib (used to treat rheumatoid arthritis)
  • ivacaftor (medicine used for treating cystic fibrosis)
  • ibrutinib (used for treating blood cancer)
  • midazolam, triazolam or similar medicines (used to induce sleep and treats anxiety)
  • olaparib (used for treating ovarian cancer)
  • methadone (used to treat chronic pain and also opioid dependence)

Overdosage:

If you or anyone else accidentally takes too much of AFFLU 150, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of AFFLU 150 are hearing, seeing, feeling and thinking things that are not real (hallucination and paranoid behaviour).

SYNOPSIS

Drug :   Fluconazole
Pharmacological Category :   Triazoles
Therapeutic Indication :   Prevent and treats various fungal infections
Dosage Forms :  

Tablet, Dispersible tablet, Capsule, Injection, Infusion, Dry syrup, Dusting powder, Gel, Cream, Ear drops, Eye drops, Soap


MORE INFORMATION

  • Keep AFFLU 150 out of reach of children
  • Store at room temperature

FAQs ABOUT AFFLU 150

How does AFFLU 150 work?

AFFLU 150 works by stopping the action of an enzyme called ergosterol, which is an integral part of the fungal cell membrane to increase its cellular permeability. Thereby, making the cell membrane more permeable and stopping the fungal growth. This type of action is useful in treating and preventing various fungal infections.

What if I forget to take a dose of AFFLU 150?

If you have missed a dose of AFFLU 150, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose of AFFLU 150 to make up for the missed one as this may increase the chances of developing side effects.

What are the common side effects of AFFLU 150?

The common side effects of taking AFFLU 150 are headache, nausea, vomiting, diarrhoea, abdominal pain, indigestion and acne. Consult your doctor if any of the symptoms get worse or does not improve over time.

Can AFFLU 150 be used in elderly patients?

AFFLU 150 should be used with caution in elderly patients particularly with renal impairment. Your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking AFFLU 150.

Is AFFLU 150 safe to use during pregnancy?

AFFLU 150 is not recommended for use during pregnancy unless clearly advised by the doctor. Consult your doctor before taking AFFLU 150 if you are pregnant or planning to get pregnant.

REFERENCES

1. KD. Tripathi. Section, Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 787.

2. Ameish Govindarajan; Karlyle G. Bistas; Curtis J. Ingold; Ayham Aboeed. NIH National Library of Medicine, National center for biotechnology information. June 2022. [Accessed on 12th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK537158

3. Josilene Chaves Ruela Corrra & Herida Regina Nunes Salgado. Review of Fluconazole Properties and Analytical Methods for Its Determination, Critical Reviews in Analytical Chemistry. May 2011. [Accessed on 12th July 2022] https://www.tandfonline.com/doi/abs/10.1080/10408347.2011.557980?journalCode=batc20

4. Viatris Ltd. Fluconazole. [Revised in March 2022] [Accessed on 12th July 2022] https://www.medsafe.govt.nz/profs/datasheet/f/fluconazolecapmylan.pdf

5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on 12th July 2022] https://www.medicines.org.uk/emc/files/pil.6086.pdf

6. FDC limited. Zocon (Fluconazole tablets) [Revised in July 2022] [Accessed on 12th July 2022] http://fdcindia.com/PackageInsert/ZoconTablets.pdf

USEFUL DIAGNOSTIC TESTS

  • Complete blood count
  • Liver function test

PRODUCT DETAILS

    Country Of Origin
    India
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AFFLU 150 Tablet 1's

AFFLU 150 Tablet 1's Mkt: Apostle Remedies

M.R.P.: Rs.9.00
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