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INTRODUCTION
ACYLIN 5% CREAM contains Acyclovir, which belongs to the group of medicines called Antivirals. It is used for the treatment of cold sores associated with the Herpes simplex virus in immunodeficiency adults and adolescents over 12 years of age. It can also be used to speed up the healing of sores and shorten the duration of pain.
A cold sore is an infection caused by the herpes simplex virus most often around the mouth. Symptoms include tiny, fluid-filled lesions called cold sores, sore lips, ulcers, blisters or rashes on the skin.
Before applying ACYLIN 5% CREAM inform your doctor if you have low immunity, cold sores in your mouth or frequent episodes of cold sores greater than 4 times a year. ACYLIN 5% CREAM is generally not recommended for use in pregnant women unless it is considered clearly necessary. ACYLIN 5% CREAM is generally not recommended for use in breastfeeding women as it may pass through the breast milk.
The most common side effects after applying ACYLIN 5% CREAM are rash, itchy skin, weal, mild drying or flaking of the skin and dry lips. Contact your doctor if your symptom gets worse or persists.
USES OF ACYLIN 5% CREAM
- Treats cold sores associated with herpes simplex virus infections
- Speeds up the healing process and shortens the duration of pain
- Treats recurrent herpes labialis (cold sores) in immunodeficiency adults and adolescents 12 years of age and above
HOW ACYLIN 5% CREAM WORKS
ACYLIN 5% CREAM works by killing or stopping the growth of viruses (herpes virus). It has a higher affinity for viral DNA cells than human DNA cells and incorporates into the viral DNA and causes DNA chain termination and inactivation, leading to the death of cells.
DIRECTIONS FOR USE
Apply ACYLIN 5% CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water before applying the medicine. Apply a thin layer of medicine to the affected area. Do not rub the cold sore because this may cause the cold sore to spread to other areas or make your cold sore worse. Use this medicine for up to 5 days.
SIDE EFFECTS OF ACYLIN 5% CREAM
COMMON
- burning or stinging feeling
- redness, itching, mild drying or flaking of the skin, skin rashes, hives and weals
- dry or cracked lips
- peeling
RARE
Stop applying ACYLIN 5% CREAM and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction symptoms such as rash, itchy skin, weal, swelling of the lips, face and/or eyelids
HOW TO MANAGE SIDE EFFECTS
Itchy skin:
Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. If the symptom does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
Inform your doctor if you are pregnant before applying ACYLIN 5% CREAM. Consult your doctor before applying.
BREASTFEEDING
ACYLIN 5% CREAM is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before applying ACYLIN 5% CREAM.
ALLERGY
Do not apply ACYLIN 5% CREAM if you are allergic to Acyclovir, Valacyclovir, or any of the other ingredients of the medicine.
OTHERS
ACYLIN 5% CREAM is not recommended for use if you have:
- mouth ulcers
- herpes infections near the eyes, or in the genital area
Before applying ACYLIN 5% CREAM, inform your doctor:
- if you have low immunity
- frequent episodes of cold sores
Use in pediatrics:
ACYLIN 5% CREAM should be used with caution in children under 12 years of age. Consult your doctor before applying ACYLIN 5% CREAM.
Use in geriatrics:
ACYLIN 5% CREAM should be used with caution in elderly patients (aged above 75 years). Consult your doctor before applying ACYLIN 5% CREAM.
INTERACTIONS
A. Drug-Drug interactions:
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplements or herbal products.
Overdosage:
If you or anyone else accidentally use too much of ACYLIN 5% CREAM or if you or a child accidentally swallow the medicine, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Acyclovir |
| Pharmacological Category | : | Antivirals |
| Therapeutic Indication | : | Cold sores |
| Dosage Forms | : | Tablet, Suspension, Syrup, Infusion, Injection, Cream, Ointment, Eye ointment |
MORE INFORMATION
- Keep ACYLIN 5% CREAM out of the sight and reach from children
- Store ACYLIN 5% CREAM below 25°C
FAQs ABOUT ACYLIN 5% CREAM
Can I apply ACYLIN 5% CREAM on genital herpes?
No. Do not apply ACYLIN 5% CREAM to any unaffected skin, or genital herpes sores. Consult your doctor before applying.
Can I use ACYLIN 5% CREAM for impetigo?
No. ACYLIN 5% CREAM is used to treat cold sores caused by the herpes simplex virus. Consult your doctor before applying ACYLIN 5% CREAM.
How long does it take for ACYLIN 5% CREAM to work?
ACYLIN 5% CREAM starts working within 24 hours of administration and symptoms gradually decrease within 3 days. Consult your doctor if the symptom persists.
Can I use ACYLIN 5% CREAM on my lips?
Yes. ACYLIN 5% CREAM is used to treat cold sores (fever blisters; blisters that are caused by a herpes simplex virus) on the face or lips. Consult your doctor before applying ACYLIN 5% CREAM.
REFERENCES
1. KD Tripathi. Antiviral drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 799.
2. CP Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2017] [Accessed on 21st April 2022] https://www.medicines.org.uk/emc/files/pil.9273.pdf
3. GlaxoSmithKline Consumer Healthcare Ireland. U.S. Food & Drug Administration. [Revised in June 2014] [Accessed on 21st April 2022] https://www.hpra.ie/img/uploaded/swedocuments/1bd6b3c8-01dc-4e0f-94d3-f738dfeb3b6c.pdf
4. GlaxoSmithKline. Health Products Regulatory Authority (HPRA). [Revised in June 2014] [Accessed on 21st April 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021478s007lbl.pdf
5. Relonchem Limited. Acyclovir. [Revised in March 2017] [Accessed on 21st April 2022] https://mhraproductsprod.blob.core.windows.net/docs/5b7af5e67daa228ce8c33859af93fd2d67b178b1
USEFUL DIAGNOSTIC TESTS
- Herpes Simplex Virus 1 DNA PCR
- Herpes Simplex Virus 1 IgG
- Herpes Simplex Virus 2 DNA PCR
- Herpes Simplex Virus 2 IgG
- Herpes Simplex Virus 2 IgM
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