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ACUCLAV IV 300mg Injection 1's

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Bacterial Infections Rx required
Amoxycillin 250 mg+Clavulanic Acid 50 mg
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MRP ₹83.40
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* Mkt: Macleods Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

INTRODUCTION

ACUCLAV IV 300MG INJECTION contains Amoxicillin and Clavulanic acid, which belong to the group of medicines called Penicillins and Beta-Lactamase Inhibitors. It is used in children for the treatment and prophylaxis of various bacterial infections (such as respiratory tract infections, which include pneumonia), acute exacerbation of chronic bronchitis, urinary tract infections (cystitis, urethritis, pyelonephritis), bone and joint infections (osteomyelitis), middle ear infections (otitis media), tonsillitis, sinusitis, skin, and soft tissue infections such as cellulitis, boils, wound infections, intra-abdominal sepsis, dental infections, infections of genital organs in females.

Along with treatment with ACUCLAV IV 300MG INJECTION, your doctor might order bacterial culture tests to enhance the outcomes of the treatment and in cases of prolonged treatment with ACUCLAV IV 300MG INJECTION, your doctor might conduct a complete blood count, and liver or kidney function test.

ACUCLAV IV 300MG INJECTION is not recommended for use in patients with severe kidney impairment, a history of liver problems or jaundice after taking penicillin antibiotics. ACUCLAV IV 300MG INJECTION should be used with caution in patients suffering from glandular fever (a viral infection causing sore throat, high fever, swelling of salivary glands etc), liver disease, kidney disease, who are not passing urine daily, convulsions (fits) or large intestine inflammation.

ACUCLAV IV 300MG INJECTION is not recommended for use in pregnant women unless necessary. ACUCLAV IV 300MG INJECTION should be used with caution in breastfeeding women as it may pass through breast milk. ACUCLAV IV 300MG INJECTION should be used with caution in neonates, and infants (less than 12 weeks of age). The most common side effects after receiving ACUCLAV IV 300MG INJECTION are diarrhoea, thrush (fungal infection), etc. Consult your doctor immediately in case any of the side effects worsen.

USES OF ACUCLAV IV 300MG INJECTION

  • Treatment and prophylactic management of various bacterial infection

HOW ACUCLAV IV 300MG INJECTION WORKS

ACUCLAV IV 300MG INJECTION helps in treating bacterial infection where Amoxicillin works by inhibiting penicillin-binding proteins (which are involved in the synthesis of the bacterial cell wall) leading to the activation of autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall and death of the bacterial cell and Clavulanic acid inhibits the activity of bacterial enzymes known as beta-lactamases and hence enhances the antibacterial activity of amoxicillin.

DIRECTIONS FOR USE

ACUCLAV IV 300MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or intravenous injection. Your doctor will decide the exact dose and duration of treatment for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF ACUCLAV IV 300MG INJECTION

COMMON

  • diarrhoea
  • thrush (candida fungal infection)

UNCOMMON

  • rashes, itching, hives (raised itch rashes)
  • urticaria
  • nausea and vomiting
  • dizziness, headache
  • indigestion
  • abnormal liver enzymes

RARE

  • erythema multiforme (skin rashes, blisters, small target rashes)
  • low number of platelets (cells that help in clotting)
  • decreased white blood cells
  • swelling and inflammation at the site of injection

Stop receiving ACUCLAV IV 300MG INJECTION and consult your doctor immediately in case you experience:

  • severe allergic reaction which includes rashes, collapsing or fainting, swelling of face, throat which may cause difficulty in breathing, fever, joint pain, swollen lymph nodes of neck, armpits, groin, red or purple raised spots on skin due to inflammation of blood vessels
  • swelling and tenderness of vein which is very painful on touching
  • watery diarrhoea with blood or mucus, fever, and abdominal pain which occurs due to inflammation of the large intestine
  • inflammation of the liver (hepatitis), jaundice (yellowing of white part of eyes, nails, skin paleness)
  • inflammation of kidney tubes
  • delayed blood clotting
  • convulsions (fits) most commonly experienced by patients suffering from kidney disease

HOW TO MANAGE SIDE EFFECTS

Diarrhea

Drink plenty of water or fruit juices to keep you hydrated. Don’t take any medicine on your own to treat diarrhoea. Consult your doctor if your symptoms get worse or persist.

Headache

Rest and relax. Drink plenty of water and electrolytes. Apply a pain-relieving balm on the head if required. Consult your doctor if your symptoms get worse or persist.

Nausea And Vomiting

Receive the medicine, before meals. Stick to simple meals. Avoid eating oily or spicy food. Consult your doctor if your symptoms get worse or persist.

Skin Rash Or Itching

Avoid hot showers because hot water can irritate the skin and does not scratch the affected area. Apply moisturizing cream, Sunscreen and use protective clothing. Consult your doctor if your symptoms get worse or persist.

WARNING & PRECAUTIONS

PREGNANCY
Monitoring required

ACUCLAV IV 300MG INJECTION is not recommended for use in pregnant women unless necessary. Consult your doctor before receiving ACUCLAV IV 300MG INJECTION.

BREASTFEEDING
Use with Caution

ACUCLAV IV 300MG INJECTION should be used with caution in breastfeeding women as it may pass through breast milk. Consult your doctor before receiving ACUCLAV IV 300MG INJECTION.

DRIVING AND USING MACHINES
Contraindicated

Do not drive or operate machinery after receiving ACUCLAV IV 300MG INJECTION.

KIDNEY
Consult your doctor

ACUCLAV IV 300MG INJECTION is not recommended for use in patients with severe kidney impairment. Consult your doctor before receiving ACUCLAV IV 300MG INJECTION.

ACUCLAV IV 300MG INJECTION should be used with caution in patients suffering from kidney problems. Consult your doctor before receiving ACUCLAV IV 300MG INJECTION.

LIVER
Consult your doctor

ACUCLAV IV 300MG INJECTION is not recommended for use in patients who had a history of liver problems or jaundice after taking penicillin antibiotics. Consult your doctor before receiving ACUCLAV IV 300MG INJECTION.

ACUCLAV IV 300MG INJECTION should be used with caution in patients suffering from, liver disease. consult your doctor before receiving ACUCLAV IV 300MG INJECTION.

ALLERGY
Contraindicated

Do not receive ACUCLAV IV 300MG INJECTION if you are allergic to Amoxicillin, Clavulanic acid, Cephalosporins or any other ingredients in this medicine.

OTHERS

Before receiving ACUCLAV IV 300MG INJECTION inform your doctor if you have:

  • glandular fever (viral infection causing sore throat, high fever, swelling of salivary glands etc)
  • not been urinating regularly
  • convulsions (fits)
  • large intestine inflammation
  • urine and blood tests

Use in Paediatrics:

ACUCLAV IV 300MG INJECTION should be used with caution in children (less than 12 weeks of age). Consult your doctor for advice.

Use in Geriatric:

ACUCLAV IV 300MG INJECTION should be used with caution in the elderly. Consult your doctor for advice.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving ACUCLAV IV 300MG INJECTION, inform your doctor if you are taking any of the following medicine:

  • medicines used to treat gout (Ex. allopurinol, probenecid)
  • medicines used to treat blood clots (Ex. warfarin)
  • methotrexate (used for the treatment of cancer, and severe psoriasis)
  • medicine used to prevent organ transplant rejection (Ex. mycophenolate mofetil)
  • medicines used for the prevention of pregnancy (oral contraceptives)

Overdosage:

ACUCLAV IV 300MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse immediately if you experience any unusual symptoms. Symptoms of an overdose of ACUCLAV IV 300MG INJECTION are nausea, diarrhoea, fits, and upset stomach.

SYNOPSIS

Drug :   Amoxicillin, Clavulanic Acid
Pharmacological Category :   Penicillins and Beta-Lactamase Inhibitors   
Therapeutic Indication :   Bacterial infections
Dosage Forms :   Tablets, Syrup, Oral Drops, Eye Drops, Ear Drops, Oral Suspension, Infusion, Dispersible Tablet, Dry Suspension, Dry Syrup, Granules

MORE INFORMATION

  • Keep ACUCLAV IV 300MG INJECTION out of reach from children
  • Store ACUCLAV IV 300MG INJECTION below 25°C

FAQs ABOUT ACUCLAV IV 300MG INJECTION

Q: What are uses of ACUCLAV IV 300MG INJECTION?

A: ACUCLAV IV 300MG INJECTION is used in adults and children for the treatment of various bacterial infections such as respiratory tract infections which includes pneumonia, Acute exacerbation of chronic Bronchitis, urinary tract infections (cystitis, urethritis, pyelonephritis), bone and joint infections (osteomyelitis), middle ear infections (otitis media), Tonsillitis, sinusitis, skin, and soft tissue infections such as cellulitis, boils, wound infections, intra-abdominal sepsis, dental infections, infections of genital organs in females. ACUCLAV IV 300MG INJECTION is also used as prophylaxis against various bacterial infections associated with major surgeries of the heart, joints, kidney, head and neck, stomach, biliary tract, intestine, and pelvic region.

Q: What are side effects of ACUCLAV IV 300MG INJECTION?

A: The most common side effects after receiving ACUCLAV IV 300MG INJECTION are vomiting, diarrhoea, thrush (fungal infection), etc. Consult your doctor immediately in case any of the side effects worsen.

Q: How ACUCLAV IV 300MG INJECTION works?

A: ACUCLAV IV 300MG INJECTION helps in treating bacterial infection where Amoxicillin works by inhibiting penicillin-binding proteins (which are involved in the synthesis of the bacterial cell wall) leading to the activation of autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall and death of the bacterial cell and Clavulanic acid inhibits the activity of bacterial enzymes known as beta-lactamases and hence enhances the antibacterial activity of amoxicillin.

Q: Is ACUCLAV IV 300MG INJECTION safe for use in pregnant and breastfeeding women?

A: No, ACUCLAV IV 300MG INJECTION is not recommended for use in pregnant women unless necessary and ACUCLAV IV 300MG INJECTION should be used with caution in breastfeeding women as it may pass through breastmilk. Consult your doctor before receiving ACUCLAV IV 300MG INJECTION.

Q: Is ACUCLAV IV 300MG INJECTION safe for use in children?

A: Yes, ACUCLAV IV 300MG INJECTION is safe for use in children but it should be used with caution in children less than 3 months of age. Consult your doctor for advice.

REFERENCES

1. KD Tripathi. Antimicrobial Drugs. Essentials of Medical Pharmacology, 7th edition. 2013. Page-723, 724.

2. Justin Evans, Maryam Hannoodee, Micah Wittler. Amoxicillin Clavulanate. National Centre for Biotechnology. NLM. National Institute of Health. Statpearls. December 2021. [Accessed on 22nd October 2022] https://www.ncbi.nlm.nih.gov/books/NBK538164/#article-17475.s5

3. GlaxoSmithKline Pharmaceuticals Limited. Amoxicillin + Clavulanic acid. [Revised in July 2022] [Accessed on 22nd October 2022] https://india-pharma.gsk.com/media/6337/augmentin-i-v.pdf

4. Cipla Limited. Amoxicillin + Clavulanic acid. [Revised in September 2019] [Accessed on 22nd October 2022] https://www.ciplamed.com/content/advent-iv-injection , https://www.ciplamed.com/print-product-pdf/24188

5. Augpen Injection (Amoxicillin + Clavulanic acid). Zuventus Healthcare Limited. [Accessed on 22nd October 2022] http://www.zuventus.co.in/doctor_wise_products_selected.aspx?Medi_Id=65

USEFUL DIAGNOSTIC TESTS

  • Bacterial culture tests
  • Complete blood count
  • Liver and kidney function test

AUTHOR DETAILS

Written By Dr. Dhivakaran R, BDS
Last updated on 04 Feb 2023 | 12:34 PM(IST)

PRODUCT DETAILS

    Country Of Origin
    India
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.