Actemra 80mg Injection 1'S

Arthritis Rx required
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Best Price* ₹ 6,180.57 MRP ₹ 7,725.71
(Inclusive of all taxes) * Mkt: Roche Products (India) Pvt Ltd * Country of Origin: NA * Delivery charges if applicable will be applied at checkout



INTRODUCTION

ACTEMRA 80MG contains Tocilizumab which belongs to a group of medicines called interleukin-6 (IL-6) receptor inhibitors. It treats rheumatoid arthritis, giant cell arteritis (GCA), active systemic juvenile idiopathic arthritis (sJIA) and polyarticular juvenile idiopathic arthritis (pJIA). This medicine also indicated for severe or life-threatening cytokine release syndrome (CRS) following chimeric antigen receptor (CAR) T-cell treatment.

Tocilizumab is an anti-human interleukin 6 (IL-6) receptor monoclonal antibody of the immunoglobulin (Ig) which blocks a cytokine called IL-6 which is found at high levels in the joints affected by rheumatoid arthritis. Before receiving ACTEMRA 80MG, tell your physician if you have liver, kidney or heart problems, are pregnant or breastfeeding. This medicine is not suitable for use in children below 2 years of age. The common side effects are nausea, headache and dizziness.

USES OF ACTEMRA 80MG

Treats,

  • rheumatoid arthritis
  • giant cell arteritis (GCA)
  • active systemic juvenile idiopathic arthritis (sJIA)
  • polyarticular juvenile idiopathic arthritis (pJIA) and
  • severe or life-threatening cytokine release syndrome (CRS) following chimeric antigen receptor (CAR) T-cell treatment

HOW ACTEMRA 80MG WORKS

Tocilizumab blocks the action of interleukin-6, a substance in the body which causes inflammation. By blocking the immune system’s attack on normal tissues, it reduces pain, joint inflammation and tiredness leading to a better quality of life.

DIRECTIONS FOR USE

ACTEMRA 80MG will be administered by your doctor or nurse by intravenously or subcutaneously. Your physician will administer the right dose depends on your health condition.

SIDE EFFECTS OF ACTEMRA 80MG

SERIOUS

  • breathing difficulty or light-headedness
  • rash, itching, hives, swelling of the lips
  • chest pain
  • yellow skin or eyes, dark brown coloured urine, pain or swelling in the upper right side of the stomach area

COMMON

  • common cold
  • sinus infections
  • headaches
  • increase or decrease in blood pressure
  • nausea
  • dizziness
  • reactions at the injection site

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.

Dizziness:

Get up and move around to feel awake and eat a healthy food to boost your energy.

 Nausea:

Take normal regular meals and do not eat spicy foods.

WARNING & PRECAUTIONS

PREGNANCY

ACTEMRA 80MG should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor for advice.

BREASTFEEDING

ACTEMRA 80MG should be used with caution during breastfeeding. Consult your doctor for advice.

DRIVING AND USING MACHINES

Do not drive or operate any machines while taking this medicine, since it may cause dizziness.

LIVER

ACTEMRA 80MG is not recommended in patients with hepatitis or active liver diseases. Consult your doctor for advice.

ALLERGY

Tell your doctor if you are allergic (hypersensitive) to Tocilizumab.

HEART DISEASE

ACTEMRA 80MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.

OTHERS

Tell your doctor before taking this medicine if you have or had:

  • active infection
  • tuberculosis
  • diabetes
  • HIV/AIDS or a weaker immune system
  • multiple sclerosis
  • history of macrophage activating syndrome (MAS)
  • abdominal pain
  • stomach, pancreas or bowel (intestine) problems or pancreatitis
  • high blood pressure
  • increase in cholesterol
  • any type of cancer
  • are scheduled to have surgery

INTERACTIONS

Tell your doctor if you are taking,

  • simvastatin, atorvastatin (treats cholesterol)
  • calcium channel blockers
  • theophylline (treats breathing problems)
  • warfarin, phenytoin (treats epilepsy)
  • ciclosporin (prevent organ rejection)
  • benzodiazepines (treats anxiety)

SYNOPSIS

Drug :   Tocilizumab
Pharmacological Category :   Antirheumatic, Disease Modifying Interleukin-6 Receptor Antagonist
Therapeutic Indication :   Cytokine release syndrome, Giant cell arteritis, Polyarticular juvenile idiopathic arthritis, Rheumatoid arthritis, Polyarticular juvenile idiopathic arthritis, Rheumatoid arthritis
Dosage Forms :   Injection

MORE INFORMATION

  • Keep out of reach of children
  • Store at 2-8°C

FAQs ABOUT ACTEMRA 80MG

How does ACTEMRA 80MG work?

It works by blocking the inflammatory effects of a protein called tumor necrosis factor alpha (TNFα) in RA and other conditions associated with inflammation.

Is ACTEMRA 80MG over the counter?

No, it is available with doctor's prescription only.

How is ACTEMRA 80MG administered?

It is administered by intravenous or subcutaneous injection by your doctor or nurse.

REFERENCES

1. Vicki Oldfield, Sohita Dhillon, Greg L Plosker. Tocilizumab: a review of its use in the management of rheumatoid arthritis. 2009. [Accessed on June 11, 2021] https://pubmed.ncbi.nlm.nih.gov/19368420/

2. Hoffmann-La Roche Limited Mississauga. [Revised on Jan 04, 2021] [Accessed on June 11, 2021] https://www.rochecanada.com/PMs/Actemra/Actemra_PM_E.pdf

3. Cipla Ltd. 29 Aug 2008. [Revised on July 2020] [Accessed on June 11, 2021] https://www.ciplamed.com/print-product-pdf/46820

4. Pan Luo, Yi Liu, 1 Lin Qiu, 1 Xiulan Liu, 1 Dong Liu and Juan Li. Tocilizumab treatment in COVID-19: A single center experience. April 15, 2020. [Accessed on June 11, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262125/

USEFUL DIAGNOSTIC TESTS

  • Anti Neutrophilic Cytoplasmic Antibody - P
  • Anti Saccharomyces Cerevisiae (ASCA), IgA
  • Anti Saccharomyces Cerevisiae (ASCA), IgG
  • C- Reactive Protein Quantitative
  • Erythrocyte Sedimentation Rate
  • HLA - B27, PCR
  • Rheumatoid Factor - Agglutination
  • Rheumatoid Factor – Turbidometry
  • Rheumatoid Factor IgG Antibody

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    20 g
    Ingredient
    TOCILIZUMAB 80MG
    Hsn Code
    30021500
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