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Drug Information for ACNOVATE Gel 15gm

What is ACNOVATE Gel used for?

ACNOVATE Gel is used for the treatment of Acne vulgaris when comedones (blackheads and whiteheads), papules (pimple) and pustules (small swelling containing pus or fluid) are present on the skin.

ACNOVATE Gel may also be prescribed for other conditions as determined by your doctor.

How does ACNOVATE Gel work?

  • Adapalene is a retinoid-like compound which
    • penetrates deep inside the skin pores and prevents the build-up of dead skin and sebum that leads to acne formation;
    • blocks the hardening processes of the outer skin layer which helps in shedding of old hardened skin cells, thereby promoting growth of new skin cells;
    • blocks the inflammatory reaction, which help to reduce soreness and irritation of skin.
  • Clindamycin belongs to lincomycin group of antibiotics. Clindamycin blocks protein synthesis in the bacteria which are responsible for causing infection of acne affected skin, thus killing the bacteria.

Combination of Adapalene with Clindamycin additively promotes healing of acne lesions and prevents formation of new lesions with clearing up of bacterial infections.

How to use ACNOVATE Gel?

  • The application of topical gel of ACNOVATE Gel depends on medical condition of an individual. Apply ACNOVATE Gel gel as prescribed by your doctor.
  • Apply ACNOVATE Gel at night before going to bed. Wash the area to be applied with water thoroughly. Make sure the skin is clean and dry before applying the medicine.
  • Take a thin film of ACNOVATE Gel gel on your fingertip and apply on the affected area gently.
  • Wash your hands properly after applying ACNOVATE Gel gel.
  • Avoid application of ACNOVATE Gel into eyes or lips.
  • Do not apply ACNOVATE Gel on cuts, abrasion or eczematous skin.
  • ACNOVATE Gel is not to be used in adolescent and children below 12 years of age.
  • Do not discontinue ACNOVATE Gel without doctor’s advice.
  • If you miss a dose of ACNOVATE Gel gel, please apply it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for the missed dose.

If you have used more ACNOVATE Gel gel than advised by your doctor or have accidentally swallowed ACNOVATE Gel gel, please contact your doctor immediately.

Symptoms of excess use of ACNOVATE Gel on skin are:

  • Skin irritation
  • Redness of skin
  • Peeling of skin
  • Discomfort on skin

What are the drugs that interact with ACNOVATE Gel?

Drugs that interact with ACNOVATE Gel:

  • Aromatic and Alcoholic agents
  • Astringents
  • Peeling agents
  • Skin abrasive cleaners
  • Skin drying agents

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of ACNOVATE Gel?

Most common side effects of ACNOVATE Gel are:

  • Dry skin
  • Irritation of the skin
  • Burning sensation of the skin
  • Redness of the skin (erythema)

Please stop application of ACNOVATE Gel gel and contact your physician immediately if you have

  • irritant contact dermatitis (blistering, cracking skin, swelling, stiffness of skin, ulcers on skin, sore skin forming crust);
  • skin discomfort, pain and swelling of skin;
  • sunburn;
  • itching of the skin;
  • peeling skin;
  • irritation, redness, itching or swelling of the eyelids;
  • flare up of acne.

This is not a comprehensive list of side effects. Consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking ACNOVATE Gel?

  • Seek doctor’s advice before taking any other drug or herbal products while on ACNOVATE Gel.
  • If you are using other medications for acne like benzoyl peroxide, erythromycin or clindamycin, they may be applied in the morning and ACNOVATE Gel may be applied at night time.
  • If you have a hypersensitivity skin reaction, please stop using ACNOVATE Gel gel immediately.
  • If you have applied ACNOVATE Gel gel by mistake into eyes, mouth, nostrils or mucous membrane, wash immediately with warm water.

You are advised not to take ACNOVATE Gel if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking ACNOVATE Gel?

Tell your doctor if

  • you are allergic to ACNOVATE Gel or to any ingredients of this medicine.
  • you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • you have a history of regional enteritis or ulcerative colitis.
  • you have a history of antibiotic-associated colitis.
  • you are planning a surgery or any procedure.
  • you are pregnant or trying to conceive or are breastfeeding.

What should you do when you have used more ACNOVATE Gel gel?

If you have used more ACNOVATE Gel gel than advised by your doctor or have accidentally swallowed ACNOVATE Gel gel, please contact your doctor immediately.

Symptoms of excess use of ACNOVATE Gel on skin are:

  • Skin irritation
  • Redness of skin
  • Peeling of skin
  • Discomfort on skin

Frequently Asked questions about ACNOVATE Gel

  1. How should ACNOVATE Gel be stored?
  2. ACNOVATE Gel should be stored below 25° C in a cool, dry place. Keep the medicine away from sunlight and do not freeze the medicine. Keep the medicine out of reach from children.

  3. Should I follow any special dietary instructions while using ACNOVATE Gel gel?
  4. There are no dietary restrictions if you are using ACNOVATE Gel gel.

  5. How long will it take for ACNOVATE Gel to work?
  6. It may take 4 to 8 weeks for ACNOVATE Gel gel to work. Please consult your doctor for more information.

  7. Can I go out in the sun while applying ACNOVATE Gel?
  8. If possible, limit your sun exposure. If you are going outside, apply sunscreen as advised by your doctor. If you are using ACNOVATE Gel in the morning, then let is dry first and then apply the sunscreen.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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