ABITATE U 250MG TABLET contains Abiraterone which belongs to a group of medicines called Androgen biosynthesis inhibitors. ABITATE U 250MG TABLET is used with prednisone/prednisolone in adult men to treat prostate cancer that has spread to other parts of the body.
ABITATE U 250MG TABLET is also to treat early stage of prostate cancer when used with androgen deprivation therapy (treatment that lowers testosterone hormone) and prednisone/prednisolone (medication) in affected individuals.
ABITATE U 250MG TABLET is not recommended for use in patients allergic to abiraterone. It is also not recommended for use in patients suffering from severe liver disease.
Before taking ABITATE U 250MG TABLET, inform your doctor if you have high blood pressure, any other blood vessel problems (such as blood pressure, stroke), swelling in the feet/ankles/legs, diabetes, lung problems (such as shortness of breath), heart problems (such as heart failure, irregular/rapid heart rate), kidney, and/or liver problems.
ABITATE U 250MG TABLET is not recommended for use in pregnant and breastfeeding women since it is intended to be used only in male patients.
ABITATE U 250MG TABLET is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 75 years/above) after consulting the doctor.
The most common side effects of taking ABITATE U 250MG TABLET are swelling in legs/feet, high blood pressure, urinary tract infection, diarrhea, indigestion, chest pain, irregular heartbeat, and/or rash. Contact your doctor if any of the symptoms worsen.
With prednisone/prednisolone:
ABITATE U 250MG TABLET is an androgen biosynthesis inhibitor which works by inhibiting the production of 17α-hydroxylase (CYP17) enzyme needed to produce testosterone (male sex hormone) which enables the growth of cancer cells in the prostate gland. Since ABITATE U 250MG TABLET suppresses the production of testosterone, the cancer cells in the prostate gland won't be able to grow thus preventing its effects on the gland in affected individuals.
Take ABITATE U 250MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Avoid taking the medicine with food. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking ABITATE U 250MG TABLET and contact your doctor if you experience any of the following side effects:
Diarrhoea:
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.
Indigestion:
Try to reduce consumption of tea, coffee, cola or alcohol and lose weight if you are obsese. Avoid smoking and do not eat three to four hours before going to bed. Consult your doctor if the symptom gets worse.
Rashes:
Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin. Consult and inform your doctor if the symptom gets worse.
ABITATE U 250MG TABLET is not recommended for use in pregnant women since it is intended to be used only in male patients. Men while having sex with pregnant women or women of childbearing potential should use condom/other effective birth control methods to prevent pregnancy or harm to the unborn child during pregnancy.
ABITATE U 250MG TABLET is not recommended for use in breastfeeding women since it is intended to be used only in male patients.
ABITATE U 250MG TABLET is unlikely to affect your ability to drive or operate machines. Consult your doctor before taking ABITATE U 250MG TABLET.
ABITATE U 250MG TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking ABITATE U 250MG TABLET.
ABITATE U 250MG TABLET is not recommended for use in patients with severe liver damage. It should be used with caution in patients with other liver diseases. Consult your doctor before taking ABITATE U 250MG TABLET.
Do not take ABITATE U 250MG TABLET if you allergic to abiraterone, and/or any other ingredients of this medicine.
ABITATE U 250MG TABLET should be used with caution in patients with lung problems such as shortness of breath. Consult your doctor before taking ABITATE U 250MG TABLET.
ABITATE U 250MG TABLET should be used with caution in patients with heart problems such as heart failure, irregular/rapid heart rate, and/or heart rhythm problem. Consult your doctor before taking ABITATE U 250MG TABLET.
Before taking ABITATE U 250MG TABLET, inform your doctor if you:
Use in Pediatrics:
ABITATE U 250MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking ABITATE U 250MG TABLET.
Use in Geriatrics:
ABITATE U 250MG TABLET should be used with caution in elderly patients (aged 75 years/above). Consult your doctor before taking ABITATE U 250MG TABLET.
A. Drug-Drug Interactions:
Before taking ABITATE U 250MG TABLET, inform your doctor, if you are taking any of the following medicine:
B. Drug-Food Interactions:
ABITATE U 250MG TABLET should not be taken with grapefruit juice since it may increase the risks of side effects.
Overdosage:
If you or anyone else accidentally takes too much of ABITATE U 250MG TABLET, contact your doctor immediately or go to a hospital straight away.
Drug | : | Abiraterone |
Pharmacological Category | : | Androgen biosynthesis inhibitors |
Therapeutic Indication | : | Prostate cancer |
Dosage Forms | : | Tablet, Injection |
What is ABITATE U 250MG TABLET used for?
ABITATE U 250MG TABLET is used with prednisone/prednisolone in adult men to treat prostate cancer that has spread to other parts of the body. It is also to treat early stage of prostate cancer when used with androgen deprivation therapy (treatment that lowers testosterone hormone) and prednisone/prednisolone (medication) in affected individuals.
Can ABITATE U 250MG TABLET be taken along with food?
No. ABITATE U 250MG TABLET should not be taken along with food since it may increase the absorption of this medicine and can increase the risk of side effects. Take this medicine one hour before or after two hours of eating the food. Consult your doctor before taking the medicine.
What are the side effects of ABITATE U 250MG TABLET?
The most common side effects of taking ABITATE U 250MG TABLET are swelling in legs/feet, high blood pressure, urinary tract infection, diarrhea, indigestion, chest pain, irregular heartbeat, and/or rash. Contact your doctor if any of the symptoms worsen.
Is ABITATE U 250MG TABLET safe to use in children?
No, ABITATE U 250MG TABLET is not recommended for use in children and adolescents (aged below 18 years). If ABITATE U 250MG TABLET is accidentally ingested by a child or adolescent, go to the hospital immediately and consult the doctor for further management.
Can ABITATE U 250MG TABLET be taken by a diabetes pateint?
ABITATE U 250MG TABLET should be used with caution in patients with high blood sugar. Consult your doctor before taking ABITATE U 250MG TABLET who may advise you to check your blood sugar level before ABITATE U 250MG TABLET is advised to be taken.
1. Beverly Moy, Richard J. Lee and Mathew Smith. Natural products in cancer chemotherapy: Hormones and related drugs. Goodman & Gilman’s: The pharmacological basics of therapeutics. 12th Edition. New York MC Graw Hill Medical 2011. Page – 1767.
2. Yasser Rehman, Jonathan E Rosenberg. Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2012. [Accessed on 26th April 2022] https://pubmed.ncbi.nlm.nih.gov/22291466/
3. Matthew R Smith, Dana E Rathkopf, Peter F A Mulders, Joan Carles, Hendrik Van Poppel, Jinhui Li, Thian Kheoh, Thomas W Griffin, Arturo Molina, Charles J Ryan. Efficacy and Safety of Abiraterone Acetate in Elderly (75 Years or Older) Chemotherapy Naïve Patients with Metastatic Castration Resistant Prostate Cancer. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. November 2015. [Accessed on 26th April 2022] https://pubmed.ncbi.nlm.nih.gov/26151676/
4. Merckle GmbH. Health Products Regulatory Authority (HPRA). [Revised in May 2022] [Accessed on 26th April 2022] http://www.hpra.ie/img/uploaded/swedocuments/80fd6aa1-a8b2-4f60-92bf-ac7a2e96c6a4.pdf
5. Biocon Biologics India Limited. ABSTET. [Revised in July 2019] [Accessed on 26th April 2022] https://www.biocon.com/docs/domestic-market-pi/onco/ABSTET%20PI.pdf
6. Azista Industries Private Limited. Abiraterone acetate 250mg tablets. [Accessed on 26th April 2022] https://www.azistaindustries.com/abiraterone-acetate-tablets-exporters/
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