Abamune 300mg Tablet 30'S

Viral infections Rx required
OUT OF STOCK

Best Price*  ₹ 1,240.51
MRP ₹1,550.64
(Inclusive of all taxes) *30 Tablet(s) in a Strip * Mkt: Cipla Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

ABAMUNE 300MG contains Abacavir which belongs to a group of anti-retroviral medicines called nucleoside analogue reverse transcriptase inhibitors (NRTIs). It is indicated to treat HIV (human immunodeficiency virus) infection. This medicine reduces the amount of virus in your body, and keeps it at a low level and also increases the CD4 cell count in your blood. CD4 cells are a type of white blood cell which is essential in helping your body to fight infection. Abacavir is a guanosine analogue which is a clinically potent anti-retroviral which leads to rapid reduction in plasma HIV-RNA count and rapid rise in CD4 cell count.

Always take this ABAMUNE 300MG exactly as prescribed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems. It is not recommended during pregnant and breastfeeding. Your doctor will prescribe the right dose depends on your child’s age and body weight. The common side effects are hypersensitivity reactions such as skin rash, nausea, vomiting, abdominal pain and diarrhea.

USES OF ABAMUNE 300MG

  • Treats HIV (Human Immunodeficiency Virus) infection

HOW ABAMUNE 300MG WORKS

ABAMUNE 300MG is a guanosine analogue which is phosphorylated to carbovir triphosphate. This interferes with HIV viral RNA-dependent DNA polymerase resulting in inhibition of viral replication. It works by decreasing the amount of HIV in blood.

DIRECTIONS FOR USE

Always take this ABAMUNE 300MG exactly as your doctor has told you. Swallow as a whole, with a glass of water and do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF ABAMUNE 300MG

SERIOUS

  • skin rash
  • fever
  • shortness of breath
  • sore throat or cough
  • nausea, vomiting, diarrhea
  • abdominal pain
  • severe tiredness or achiness
  • generally feeling ill

RARE

  • inflammation of the pancreas (pancreatitis)

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

WARNING & PRECAUTIONS

PREGNANCY

ABAMUNE 300MG is not recommended for use in pregnant women, it may cause side effects in unborn babies. Discuss the risks and benefits with your doctor.

BREASTFEEDING

ABAMUNE 300MG is not recommended for use in breastfeeding, because HIV infection can be passed on to the baby in breast milk. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or handle any machines unless you are feeling well.

ALCOHOL

Consumption of alcohol is not recommended during treatment with ABAMUNE 300MG.

KIDNEY

ABAMUNE 300MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER

ABAMUNE 300MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY

Do not take if you are allergic (hypersensitive) to Abacavir.

HEART DISEASE

ABAMUNE 300MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.

OTHERS

Inform your doctor, if you have or had:

  • hepatitis B or C
  • are seriously overweight (especially if you are woman)
  • high blood pressure
  • diabetes

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

  • rifampicin (used to treat bacterial infections)
  • phenobarbital or phenytoin (used to treat epilepsy)
  • methadone (used as a heroin substitute)

SYNOPSIS

Drug :   Abacavir
Pharmacological Category :   Antiretroviral, Reverse Transcriptase Inhibitor, Nucleoside
Therapeutic Indication :   HIV-1 infection
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ABAMUNE 300MG

How does ABAMUNE 300MG work?

It interferes with an enzyme called reverse transcriptase (RT), which is used by HIV-infected cells to make new viruses.

What is the toxicity of ABAMUNE 300MG?

The most common symptoms of hypersensitivity reactions are fever, rash, nausea, vomiting, diarrhea or abdominal pain and tiredness.

What if I forget to take a dose of ABAMUNE 300MG?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one.

REFERENCES

1. KD Tripathi MD.  Antimicrobial drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 808.

2. Flexner C. Antiretroviral Agents and Treatment of HIV Infection. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. Page - 1635-1637.

3. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page - 856-857.

4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 1-2.

5. Mario Cruciani, Carlo Mengoli, Marina Malena, Giovanni Serpelloni, Saverio G. Parisi, Graeme Moyle, Oliviero Bosco. Virological efficacy of abacavir: systematic review and meta-analysis: Journal of Antimicrobial chemotherapy. Volume 69, Issue 12, December 2014; [Accessed Jan 9, 2021] https://academic.oup.com/jac/article/69/12/3169/818477

6. Mylan, Potters Bar (UK). Pharmadox Healthcare Limited. Electronic Medicines Compendium (EMC); [Revised Oct, 2019] [Accessed Jan 9, 2021] https://www.medicines.org.uk/emc/files/pil.9079.pdf

7. GlaxoSmithKline. ViiV Healthcare. 1998; U.S. Food & Drug Administration; [Revised March, 2012] [Accessed Jan 9, 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020977s024,020978s028lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • HIV 1 & 2, Ab Western Blot
  • HIV 1 And 2 Antibody - Chromatography
  • HIV 1 And 2 Antibody - ELISA

PRODUCT DETAILS

    Net Qty
    1 N
    Shelf Life
    24 Months
    Item Weight
    40 g
    Ingredient
    Abacavir 300mg
    Hsn Code
    30049099
ALTERNATE BRANDS
A Bec 300mg Tablet 30'S
Prescription Infection Rx required
Rs.1,588.00
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