WHAT IS CURCUMIN?Curcumin (/'k?rkju?m?n/, diferuloylmethane) is a bright yellow chemical produced by some plants. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family (Zingiberaceae). It is sold as an herbal supplement, cosmetics ingredient, food flavoring, and food coloring. As a food additive, its E number is E100.It was isolated in 1815 when Vogel and Pelletier reported the isolation of a "yellow coloring-matter" from the rhizomes of turmeric and named it curcumin. Although curcumin has been used historically since thousands of years in Indian Ayurvedic medicine.BENEFITS OF CURCUMINCurcumin, which shows positive results in most drug discovery assays. In vitro, curcumin has been shown to inhibit certain epigenetic enzymes (the histone deacetylases: HDAC1, HDAC3, HDAC8), transcriptional co-activator proteins (the p300 histone acetyltransferase), and the arachidonate 5-lipoxygenase enzyme.In Phase I clinical trials, curcumin was shown to exhibit poor bioavailability, exhibited by rapid metabolism, low levels in plasma and tissues, and extensive rapid excretion, factors that make its in vivo activity poorly understood. Potential factors that limit the bioavailability of curcumin include insolubility in water (more soluble in alkaline solutions) and non-absorption.- Composition: Our enhanced formula delivers 400 mg curcumin complex added 5mg Piperine (No added turmeric powder) per serving includes 95% curcuminoids and 95% Piperine, the most potent compounds in turmeric root with powerful antioxidant properties.- Anti-inflammatory: Curcumin has been studied for its anti-inflammatory capabilities especially in the treatment of rheumatoid arthritis, ulcerative colitis and other inflammatory conditions.- Cancer benefits: Dietary polyphenols like piperine and curcumin have been studied for their effect on prevention of breast cancer. Mammosphere formation, which is a marker of breast stem cells were studied.- Organic: 100% all natural and pure vegetarian dietary supplements made with Organic Turmeric Curcumin Extract and black pepper extract with 95% piperine. It has NO GMOs, BINDERS, FILLERS, or PRESERVATIVESRECOMMENDED DOSAGE: ONE(1) CAPSULE ONCE A DAY BEFORE SLEEPING OR AS SUGGESTED BY A PHYSICIAN/DOCTOR.WARNINGS: KEEP THE PRODUCT OUT OF REACH OF CHILDREN. DO NOT EXCEED RECOMMENDED DOSAGE. PREGNANT OR NURSING MOTHERS, CHILDREN UNDER THE AGE OF 18 YRS AND INDIVIDUALS WITH A KNOWN MEDICAL CONDITION SHOULD CONSULT A PHYSICIAN/DOCTOR BEFORE USIONG THIS OR ANY DIETARY SUPPLEMENT. DO NOT USE IF SAFTY SEAL IS DAMAGED OR MISSING.THIS IS NOT A SUBSTITUTE TO YOUR ONGOING MEDICATION, KINDLY KEEP TAKING YOU MEDICATION.STORAGE: Store at a temperature not exceeding 25 degrees, protect from heat & moisture. KEEP OUT OF REACH OF CHILDREN.SHELF LIFE: Best before 24 months from the date of manufacture.