INTRODUCTION

BIORAN RAPID 50MG contains Diclofenac which belongs to a group of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) which used to reduce pain and inflammation. It is used to treat sprains, strains and other injuries, pain and inflammation following surgery, gout and other painful conditions affecting the joints and muscles such as backache, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and pyrophosphate arthropathy. It is also be used to relieve the symptoms associated with migraine attacks in adults.

Diclofenac is a NSAID which exhibits anti-inflammatory analgesic and antipyretic activities. It involves inhibition of cyclooxygenase (COX-1 and COX-2) and it is a potent inhibitor of prostaglandin synthesis in vitro. Prostaglandins sensitize afferent nerves and potentiate the action of bradykinin in inducing pain and mediators of inflammation. Diclofenac is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues.

Always take BIORAN RAPID 50MG exactly as directed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems, are pregnant or breastfeeding. It is not recommended for children and adolescents below 14 years of age. The common side effects are stomach pain, heartburn, nausea, vomiting, diarrhoea and dizziness.

USES OF BIORAN RAPID 50MG

Treats,

• sprains, strains and other injuries
• pain and inflammation following surgery
• gout and other painful conditions affecting the joints and muscles such as backache, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and pyrophosphate
• also relieve the symptoms associated with migraine attacks

HOW BIORAN RAPID 50MG WORKS

BIORAN RAPID 50MG works by blocking the action of enzyme cyclooxygenase, which is required for the biosynthesis of prostaglandins.

DIRECTIONS FOR USE

Always take BIORAN RAPID 50MG exactly as your doctor has told you. Swallow this medicine with a glass of water and do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF BIORAN RAPID 50MG

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Headache:

Rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, dark room.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Stomach pain:

Place a warm water bottle on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor if you are using or have recently taken any other medicines, including medicines obtained without a prescription or the following,

• warfarin, heparin (used to treat blood clot)
• aspirin or ibuprofen (used for inflammation or pain)
• medicines to treat diabetes
• diuretics
• lithium, serotonin re-uptake inhibitors (used to treat anxiety and depression)
• digoxin (used for heart problems)
• methotrexate, ciclosporin, pemetrexed and tacrolimus (used for inflammation and cancers)
• quinolone antibiotics (used to treat some infections)
• mifepristone (used to terminate pregnancy)
• zidovudine (used to treat HIV)
• phenytoin (used to treat seizures)
• colestipol and cholestyramine (used to treat cholesterol)
• sulfinpyrazone and voriconazole

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT BIORAN RAPID 50MG

What is BIORAN RAPID 50MG used for?

It is a used to reduce inflammation and treat aches and pains in joints, muscles and bones.

What are the side effects of BIORAN RAPID 50MG?

The common side effects are nausea, vomiting, abdominal pain, diarrhea and allergic reactions. If this reaction persists, consult your doctor for advice.

Is BIORAN RAPID 50MG safe?

It is safe if used at prescribed doses for the prescribed duration as directed by the doctor.

REFERENCES

1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page: 626.

2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page: 986-987.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page: 295-297.

4. R. Andrew Moore and Sheena Derry. Diclofenac Potassium in Acute Postoperative Pain and Dysmenorrhoea: Results from Comprehensive Clinical Trial Reports. Jan 17, 2018; [Accessed on Jan 22, 2021]   

5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC); [Revised on Aug, 2020] [Accessed on Jan 22, 2021] https://www.medicines.org.uk/emc/files/pil.5791.pdf