Uses of Palonosetron

Palonosetron is used to control nausea and vomiting that occurs as a result of chemotherapy (treatment of cancer) and also used for Postoperative nausea and vomiting following surgery in adults.

Therapeutic Category

Palonosetron: Serotonin antagonists

How Palonosetron works

Palonosetron blocks the action of serotonin, that induces nausea and vomiting (serotonin is a chemical that carries messages between nerve cells in the brain and throughout the body).

Common side effects of Palonosetron

• Headache
• dizziness
• constipation
• diarrhoea
• heart rhythm changes (QT prolongation) or slow heartbeat

When to consult your doctor

Consult your doctor if you experience:

• serious allergic reaction
• In case of accidental overdosage or ingestion

Health Tips for Palonosetron

• Take palonosetron as directed, usually one hour before chemotherapy or surgery, unless otherwise instructed by your doctor
• Alcohol and some medications may interact with palonosetron, potentially affecting its effectiveness or causing unwanted side effects. Inform your doctor about all the medications, supplements, and herbal products you are taking to ensure there are no potential interactions
• Nausea and vomiting can lead to dehydration, so it's essential to drink plenty of fluids, especially after chemotherapy or surgery
• Let your doctor know if you are pregnant or planning for pregnancy or breast feeding