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Octreotide is used to treat acromegaly (a condition in which the body produces too much growth hormone), neuroendocrine tumours in the gut (Ex. appendix, small intestine or colon), and pituitary tumours that make too much thyroid-stimulating hormone (TSH). Octreotide is also used to prevent complications after surgery of the pancreas, to stop bleeding, and protect from re-bleeding from ruptured gastro-oesophageal varices (abnormal veins) in patients suffering from cirrhosis (chronic liver disease), and to relieve symptoms associated with excess production of certain hormones and other related substances by the stomach, bowels or pancreas.
Octreotide relieves the symptoms of acromegaly and overproduction of other hormones by inhibiting the release of certain hormones such as growth hormone and also by reducing the size of pituitary gland (which is enlarged in acromegaly). Octreotide also helps to control bleeding and reduce transfusion requirements in patients with ruptured gastro-oesophageal varices.
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