Uses of Octreotide

Octreotide is used to treat acromegaly (a condition in which the body produces too much growth hormone), neuroendocrine tumours in the gut (Ex. appendix, small intestine or colon), and pituitary tumours that make too much thyroid-stimulating hormone (TSH). Octreotide is also used to prevent complications after surgery of the pancreas, to stop bleeding, and protect from re-bleeding from ruptured gastro-oesophageal varices (abnormal veins) in patients suffering from cirrhosis (chronic liver disease), and to relieve symptoms associated with excess production of certain hormones and other related substances by the stomach, bowels or pancreas.

Therapeutic Category

Octreotide: Octapeptides

How Octreotide works

Octreotide relieves the symptoms of acromegaly and overproduction of other hormones by inhibiting the release of certain hormones such as growth hormone and also by reducing the size of pituitary gland (which is enlarged in acromegaly). Octreotide also helps to control bleeding and reduce transfusion requirements in patients with ruptured gastro-oesophageal varices.

Common side effects of Octreotide

• diarrhea, stomach pain, nausea, constipation, wind, loss of appetite
• headache, dizziness
• local pain at the injection site
• stomach discomfort after meal, vomiting, feeling of fullness in the stomach
• fatty or loose stools, discolored feces
• hair loss
• shortness of breath
• weakness

When to consult your doctor

Consult your doctor:

• in case of accidental overdosage
• if you experience gallstones (causing sudden back pain)
• if you experience excess or low blood sugar
• if you experience hypothyroidism (underactive thyroid gland which causes changes in heart rate, appetite or weight, tiredness, feeling cold, or swelling at the front of the neck)
• if you experience cholecystitis (inflammation of the gallbladder causing pain in the upper right abdomen, fever, nausea, yellowing of the skin and eyes)
• if you experience impaired glucose tolerance
• if you experience slow heartbeat

Health Tips for Octreotide

• Maintain adequate hydration by drinking enough fluids unless advised otherwise by the doctor
• Living with a chronic disease can be challenging. Consider joining support groups or seeking emotional support from friends, family, or healthcare professionals. They can provide valuable guidance, understanding and encouragement