Uses of Lapatinib

Lapatinib is used to block the action of proteins that are responsible for metastatic breast cancer (cancer that has been spread to other parts of the body from breast). It is mostly used in combination with other anticancer or hormonal medicines (such as capecitabine, trastuzumab or anastrozole) to achieve better results.

Therapeutic Category

Lapatinib: Anticancer agents

How Lapatinib works

Lapatinib is an anticancer agent. It works by blocking the actions of certain cellular proteins (tyrosine kinase) that triggers cancer cell formation. It also blocks various downstream cell signalling pathways that triggers cancer growth within the body. As a result, it reduces cancer formation and prevents its further growth within the body.

Common side effects of Lapatinib

• nausea, vomiting, loss of appetite
• tiredness, weakness
• indigestion, constipation, stomach pain
• sore mouth, trouble sleeping
• back pain, pain in hands and feet, joint pain
• skin reaction on the palms of the hands or soles of the feet (including tingling, numbness, pain, swelling or reddening)
• headache
• nose bleeds, hot flushes
• unusual hair loss or thinning
• nail disorder
• abnormal heartbeat

When to consult your doctor

Consult your doctor:

• In case of accidental overdosage
• If you experience signs of allergic reactions (such as skin rash, itching, swelling of the face, lips, tongue and throat causing difficulty in breathing or swallowing)
• If you experience severe diarrhea
• If you experience severe skin rash with skin dryness and itching
• If you experience severe cough and shortness of breath (signs of lung damage)

Health Tips for Lapatinib

• Take lapatinib exactly as prescribed by your doctor. Follow the recommended dosage, timing, and frequency
• Take the medication at the same time each day to maintain consistent levels in your body
• Lapatinib should be taken on an empty stomach, at least one hour before or one hour after a meal
• Grapefruit and grapefruit juice can interact with lapatinib and affect its effectiveness. Avoid consuming grapefruit products while on this medication
• Be vigilant for any potential side effects such as diarrhea, nausea, vomiting, rash, fatigue, or changes in heart rhythm. Notify your healthcare provider if you experience any of these symptoms
• Drink plenty of fluids to stay hydrated, especially if you experience diarrhea or other side effects that could lead to dehydration
• Sun Protection: Lapatinib can increase sensitivity to sunlight. Protect your skin by using sunscreen, wearing protective clothing, and avoiding prolonged sun exposure